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Levofloxacin Hydrochloride Eye Drops

Function and Efficacy

Levofloxacin is the left-handed isomorph of ofloxacin, and its antibacterial activity is about twice that of ofloxacin. Its main mechanism of action is to inhibit the activity of bacterial topoisomerase IV and DNA gyrase (both are type II topoisomerases), thereby hindering the replication of bacterial DNA and achieving its antibacterial effect.

Ingredients

Levofloxacin Hydrochloride

Name Description Content CAS NO. Manufacturer
Levofloxacin hydrochlorideIngredients

It achieves antibacterial effect by inhibiting the activity of bacterial topoisomerase IV and DNA gyrase, hindering the replication of bacterial DNA

More
177325-13-2 18

Appearance

This product is a light yellow-green clear liquid.

Indication

This product is suitable for the treatment of bacterial conjunctivitis and bacterial keratitis caused by sensitive bacteria.

Usage and Dosage

Drop the product into the conjunctival sac of the affected eye. 3-5 times a day, 1-2 drops each time. Recommended course of treatment: 7 days for bacterial conjunctivitis, 10-14 days for bacterial keratitis. Or follow the doctor's advice.

Adverse Reactions

The most commonly reported adverse reactions are temporary decreased vision, fever, transient eye burning, eye pain or discomfort, pharyngitis and photophobia, with an incidence of about 1% to 3%. Adverse reactions with an incidence of less than 1% include: allergies, eyelid edema, dry eyes and itching.

Precautions

Patients who are allergic to levofloxacin hydrochloride or other quinolones or any components of this product are contraindicated.

Special Population Medication

Precautions for children: The efficacy and safety of this product for infants under 1 year old have not been established. Oral administration of quinolones to immature animals can cause arthritis, but there is no evidence that levofloxacin eye drops have any effect on weight-bearing joints. Precautions for pregnancy and lactation: Since there is insufficient research and data on the use of this product in pregnant women, it is not recommended for pregnant women. Based on the data of ofloxacin, it is speculated that levofloxacin can be excreted through human breast milk, so it should be used with caution in lactating women. Precautions for the elderly: There is no overall difference in the efficacy and safety of this product for the elderly and other adult patients.

Drug Interactions

There is still a lack of information on drug interactions with this product. However, it has been shown that some quinolones can increase the blood concentration of theophylline when administered systemically, interfere with the metabolism of caffeine, and increase the effects of oral anticoagulants such as warfarin and its derivatives. If cyclosporine is taken at the same time, patients may experience a transient increase in serum creatinine.

Storage

Keep away from light, tightly closed, in a cool place.

Packaging Specification

5ml:15mg (calculated as levofloxacin)

Validity Period

24 months

Manufacturer

Shandong Bausch & Lomb Freda Pharmaceutical Co., Ltd.

  • Founded in:

    1992-03-31
  • Address:

    No. 789, Xinluo Street, Jinan High-tech Development Zone
  • Tax NO.:

    913701006140705563
  • Registered Funds:

    90 million yuan
  • Website:

  • Email:

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