Oxybuprocaine hydrochloride eye drops
Function and Efficacy
1. Anesthetic effect and duration After 6 healthy people were given one drop of this agent, the time required to achieve complete anesthesia was measured. The results showed that the average onset time was 9 minutes [the average pain-free duration was 13 minutes and 4 seconds]. 2. Surface anesthetic intensity The corneal anesthesia test conducted on rabbits showed that the surface anesthetic intensity of oxybuprocaine hydrochloride was about 20 times that of cocaine. In addition, the infiltration anesthetic effect of this product on mouse skin is about 10 times that of procaine. 3. Others The corneal damage effect of this agent is weaker than that of cocaine, tetracaine, etc., and it has no effect on pupil diameter, accommodation function, light perception, intraocular pressure, etc.
Ingredients
Benoxil 0.4% solution is a colorless to slightly yellowish brown clear aqueous eye drop containing 0.4% oxybuprocaine hydrochloride. This medicine contains disodium edetate, benzalkonium chloride and polyvinyl alcohol (partial saponification) as additives.
| Name | Description | Content | CAS NO. | Manufacturer |
|---|---|---|---|---|
| Benoxinate HydrochlorideIngredients |
The intensity of surface anesthesia is about 20 times that of cocaine, and the infiltration anesthetic effect on mouse skin is about 10 times that of procaine. The corneal damage effect is weaker than that of cocaine, tetracaine, etc., and it has no effect on pupil diameter, accommodation function, light perception, intraocular pressure, etc. More |
5987-82-6 | 5 | |
| Ethylenediaminetetraacetic acid disodium saltExcipients |
1. Anesthetic effect and duration After 6 healthy people were given one drop of this agent, the time required to achieve complete anesthesia was measured. The results showed that the average onset time was 9 minutes [the average pain-free duration was 13 minutes and 4 seconds]. 2. Surface anesthetic intensity The corneal anesthesia test conducted on rabbits showed that the surface anesthetic intensity of oxybuprocaine hydrochloride was about 20 times that of cocaine. In addition, the infiltration anesthetic effect of this product on mouse skin is about 10 times that of procaine. 3. Others The corneal damage effect of this agent is weaker than that of cocaine, tetracaine, etc., and it has no effect on pupil diameter, accommodation function, light perception, intraocular pressure, etc. More |
139-33-3 | 18 | |
| Benzalkonium ChlorideExcipients |
1. Anesthetic effect and duration After 6 healthy people were given one drop of this agent, the time required to achieve complete anesthesia was measured. The results showed that the average onset time was 9 minutes [the average pain-free duration was 13 minutes and 4 seconds]. 2. Surface anesthetic intensity The corneal anesthesia test conducted on rabbits showed that the surface anesthetic intensity of oxybuprocaine hydrochloride was about 20 times that of cocaine. In addition, the infiltration anesthetic effect of this product on mouse skin is about 10 times that of procaine. 3. Others The corneal damage effect of this agent is weaker than that of cocaine, tetracaine, etc., and it has no effect on pupil diameter, accommodation function, light perception, intraocular pressure, etc. More |
63449-41-2 | 6 |
Appearance
Colorless to slightly yellowish brown clear aqueous eye drops
Indication
Topical anesthesia in ophthalmology.
Usage and Dosage
Generally, adults should use 1 to 4 drops. The dosage can be increased or decreased according to age and physical condition.