Benzbromarone Tablets
Function and Efficacy
This product is a benzofuran derivative and a uricosuric drug. Its mechanism of action is mainly to inhibit the reabsorption of uric acid by the renal tubules, thereby reducing the concentration of uric acid in the blood.
Ingredients
The main ingredient of this product is benzbromarone.
| Name | Description | Content | CAS NO. | Manufacturer |
|---|---|---|---|---|
| BenzbromaroneIngredients |
This product is a benzofuran derivative and a uricosuric drug. Its mechanism of action is mainly to inhibit the reabsorption of uric acid by the renal tubules, thereby reducing the concentration of uric acid in the blood. More |
3562-84-3 | 8 |
Appearance
This product is a white tablet.
Indication
①Primary hyperuricemia and gout caused by various reasons. ②Secondary hyperuricemia.
Usage and Dosage
Adults take 50 mg orally once a day after breakfast. Check the patient's serum uric acid concentration after 1-3 weeks of medication. When it drops to the normal range, change to 50-100 mg per day, or follow the doctor's advice.
Adverse Reactions
A few people may experience a decrease in blood granulocytes. Occasionally, there may be diarrhea, abdominal distension, nausea, upper abdominal pain, etc. It is reported that 1% have diarrhea and 0.8% have gastrointestinal dysfunction (abdominal pain, nausea, fullness, upper abdominal pain, occasional vomiting). Occasionally, renal colic and allergic rash are seen. 1.36% of patients stop treatment due to intolerance. In very rare cases, drug resistance and persistent diarrhea may occur.
Precautions
1 Patients with moderate to severe renal impairment (glomerular filtration rate less than 20ml/min) and patients with kidney stones. 2 Pregnant women, women who may become pregnant, and breastfeeding women are prohibited from using this product.
Special Population Medication
Precautions for children: The safety and effectiveness of this product for children have not been studied, so it is not recommended for children. Precautions for pregnancy and lactation: 1. Since there is no clinical experience in humans and there are deviations in animal experimental results, it is contraindicated for pregnant patients. 2. It is not clear whether benzbromarone enters breast milk, so it is contraindicated for lactating patients. Precautions for the elderly: The physiological functions of the elderly generally decline, so the dosage should be reduced or follow the doctor's advice.
Drug Interactions
The uricosuric effect of benzbromarone may be attenuated by salicylates and sulfinpyrazone.
Storage
Keep sealed.
Packaging Specification
50 mg
Validity Period
60 months
Manufacturer
Yichang HEC Changjiang Pharmaceutical Co., Ltd.
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Founded in:
2001-08-08 -
Address:
No. 38, Binjiang Road, Yidu City, Yichang City, Hubei Province -
Tax NO.:
91420000730842584F -
Registered Funds:
879.9677 million yuan -
Website:
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Email: