Naproxen Sodium Tablets

Naproxen has dose-dependent anti-inflammatory, analgesic and antipyretic effects. The intensity of the anti-inflammatory effect is about 11 times that of the same dose of phenylbutazone, and the analgesic and antipyretic effects are 7 and 22 times that of aspirin. The anti-inflammatory, analgesic and antipyretic effects are equivalent to indomethacin. The mechanism of action of naproxen is that it inhibits COX activity and thus inhibits PG synthesis, but its selective inhibition of COX2 is stronger, so it has a strong anti-inflammatory effect and less gastrointestinal adverse reactions.

The main ingredient is: Naproxen sodium. Its chemical name is: sodium a-methyl-6-methoxy-2-naphthylacetate.

This product is white or off-white tablets.

Used to relieve mild to moderate pain, such as joint pain, neuralgia, muscle pain, migraine, headache, dysmenorrhea, and toothache.

Oral administration: Adults, 2 tablets for the first time, 1 tablet each time thereafter, and once every 6-8 hours if necessary.

1. Skin itching, shortness of breath, dyspnea, asthma, tinnitus, lower limb edema, stomach burning sensation, indigestion, stomach pain or discomfort, constipation, dizziness, drowsiness, headache, nausea and vomiting, etc., with an incidence of 3% to 9%. 2. Blurred vision or visual impairment, hearing loss, diarrhea, oral irritation or pain, palpitations and sweating, etc., with an incidence of 1% to 3%. 3. Gastrointestinal bleeding, kidney damage (allergic nephritis, pain disease, renal papillary necrosis and renal failure, etc.), urticaria, allergic rash, depression, muscle weakness, bleeding or granulocytopenia and liver damage, etc. are less common, with an incidence of 1% to 3%.

It is prohibited for people who are allergic to aspirin, and should be used with caution by those with peptic ulcer or history of peptic ulcer.

Precautions for children: The common dosage for children is 10 mg/kg per day for rheumatism, divided into 2 doses. Precautions for pregnancy and lactation: Forbidden. Precautions for the elderly: Not yet clear.

1. When used with alcohol or other anti-inflammatory drugs, gastrointestinal adverse reactions increase and there is a risk of ulcers. 2. When used with anticoagulants such as heparin and dicoumarol, the bleeding time is prolonged, bleeding tendency may occur, and there is a possibility of causing gastrointestinal ulcers. 3. When used with aspirin or other salicylic acid preparations, it does not enhance symptom relief, but increases gastrointestinal adverse reactions. 4. This product can reduce the sodium excretion and hypotensive effects of furosemide. 5. This product can inhibit the excretion of lithium in urine, increasing the blood concentration of lithium. 6. When used with probenecid, the blood concentration of this product increases, t1/2 is prolonged, and the efficacy can be increased, but the toxicity reaction is also increased accordingly, so it has no practical value and should not be recommended in clinical practice.

Protect from light, seal tightly and store in a cool place.

0.1g (equivalent to 91mg of naproxen)

36 months

Chifeng Mysun Pharmaceutical Co., Ltd.

• Founded in:

  2001-11-28

• Address:

  No. 1, Mengxin Street, Hongshan Economic Development Zone, Chifeng

• Tax NO.:

  91150402114795518Q

• Registered Funds:

  44.22 million yuan

• Email:

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