Dosimol Tablets

Dosimab ester is a gastric mucosal protective drug, and its mode of action is the same as that of sucralfate, acting directly on the gastric mucosa without anti-secretory effect. Dosimab ester forms a protective film covering the mucosal surface, and at the same time generates a pepsin complex to reduce damage; it also increases the concentration of PGE2 in gastric juice. [Pharmacokinetics] Dosimab ester is virtually not absorbed after oral administration in rats, and no dosimab ester was detected in the plasma or urine of the administered animals; 12 hours after oral administration, it can actually be completely recovered in the feces, and the excretion half-life is 5-6 hours. Human studies have also shown that after oral administration of dosimab ester, the acidic organic part of the dosimab ester structure was not detected at a significant level in any plasma sample by HPLC. After oral administration of 8g of dosimab ester, the cumulative clearance in urine was less than 0.04% within 72 hours, and the detection limit was 0.1μg/ml.

Molecular weight: Al7(OH)14(C28H25O36S7[Al(OH)3]7

This product is a yellow tablet.

This product is used to treat gastric and duodenal ulcers.

Oral administration, twice a day, 1.5 g (three tablets) each time.

A small number of patients may experience nausea and vomiting, abdominal pain, diarrhea, stomach distension, acid reflux, heartburn, belching, rash, constipation, etc.

Not yet clear.

Precautions for children: Not yet clear. Precautions for pregnancy and lactation: Not yet clear. Precautions for the elderly: Not yet clear.

1. Proton pump inhibitors such as omeprazole and antacids such as aluminum hydroxide should be taken at least 30 minutes after taking dosimab. 2. Quinolone antibiotics such as ciprofloxacin, norfloxacin, etc. should be taken 2 to 6 hours before or 4 hours after taking dosimab, because this product can form insoluble compounds. 3. The antifungal drug ketoconazole should be taken at least 2 hours before taking dosimab. 4. Digoxin should be taken at least 2 hours before taking dosimab, because it may reduce the absorption of digoxin due to an uncertain process of action. Quinidine should be taken at least 4 hours before taking dosimab, because this product will reduce its absorption. Tetracycline should be taken 2 to 3 hours before taking dosimab. 5. This product can reduce the oral hypoglycemia

Store in a sealed, cool, dark and dry place

0.5g

24 months

Xiangbei Welman Pharmaceutical Co., Ltd.

• Founded in:

  1995-09-26

• Address:

  Dongyang Township, Liuyang City, Hunan Province (inside the Biomedical Park)

• Tax NO.:

  914301006166609551

• Registered Funds:

  365.925 million yuan

• Website:

  Log in to view

• Email:

  Log in to view