Metronidazole extended-release tablets
Function and Efficacy
After entering the body, metronidazole is acted upon by intracellular ion transporters, which form a concentration gradient that promotes the transport of drugs into cells. The drug forms free radicals in the cell, which in turn react with intracellular components and eventually lead to the death of microorganisms. Gram-positive anaerobic bacteria: Clostridium, Eubacterium, Peptococcus nigra, Peptostreptococcus. Gram-negative anaerobic bacteria: Bacteroides fragilis (type species, Bacteroides divaricata, Bacteroides ovatus, Bacteroides thetaiotaomicron and Bacteroides vulgaris), Prevotella (Prevotella biloba, Prevotella buccalis, Prevotella saccharolyticus), Porphyromonas, Fusobacterium. Parasitic protozoa: Entamoeba histolytica, Trichomonas vaginalis.
Ingredients
The main ingredient is metronidazole.
Appearance
This product is a light yellow oval film-coated tablet, which appears off-white after removing the coating.
Indication
Treat bacterial vaginosis in women.
Usage and Dosage
Oral administration: 750 mg (1 tablet) once a day for seven consecutive days, with seven days as a course of treatment. Metronidazole sustained-release tablets should be swallowed whole on an empty stomach at least 1 hour before or 2 hours after a meal. Taking on an empty stomach can maintain the best sustained-release properties of this product.
Adverse Reactions
Most adverse events were mild to moderate, including headache, nausea, metallic taste, and vulvar and vaginal candidiasis.
Precautions
People who are allergic to metronidazole or other nitroimidazole derivatives; women who are pregnant within three months.
Special Population Medication
Precautions for children: The safety of metronidazole extended-release formulations in children has not been determined. Precautions for pregnancy and lactation: The decision to terminate lactation or stop medication should be made based on the importance of the drug and the mother. Precautions for the elderly: It is necessary to monitor blood drug levels in elderly patients to adjust the metronidazole dosage.
Drug Interactions
Drug interactions may occur if used with other drugs. Please consult your doctor or pharmacist for details.
Storage
seal.
Packaging Specification
0.75g
Validity Period
24 months
Manufacturer
Venturpharm Pharmaceutical(Hainan)Limited.
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Founded in:
2004-03-09 -
Address:
No. 279 Nanhai Avenue, Haikou City -
Tax NO.:
914601007543894388 -
Registered Funds:
194.8706 million yuan -
Email: