Loratadine Sustained-Release Tablets

This product is a compound preparation of loratadine and pseudoephedrine. Loratadine is a long-acting tricyclic antihistamine that can relieve nasal or non-nasal symptoms of seasonal allergic rhinitis by selectively antagonizing peripheral H1 receptors. Pseudoephedrine sulfate is an adrenergic drug that can constrict nasal mucosal blood vessels and relieve symptoms of nasal congestion and runny nose. Toxicological studies on loratadine genetic toxicity: No mutagenic effect of loratadine was observed in the Ames test, forward point mutation test, DNA damage test, and chromosome aberration test. In the mouse lymphoma test, positive results appeared in the inactive state and negative in the activated state. Reproductive toxicity: Male rats were orally administered loratadine at a dose of 64 mg/kg (converted to body surface area,

This product is a compound preparation, its components are 10 mg of loratadine and 248 mg of pseudoephedrine sulfate.

This product is white or off-white tablets.

Used to relieve symptoms such as nasal congestion, itchy nose, sneezing, runny nose and tearing caused by allergic rhinitis or colds.

Oral administration: Adults and children over 12 years old, take one tablet each time, once a day.

The use of this product may cause dry mouth and insomnia. Other occasional symptoms include headache, dizziness, fatigue, nausea, abdominal discomfort, vomiting, tachycardia, facial flushing, agitation, etc.

1 This product is contraindicated in patients with allergic or specific reactions to the ingredients contained in this product, adrenergic drugs or other drugs with similar chemical structures. 2 This product is also contraindicated in patients who are receiving monoamine oxidase inhibitor therapy or have received such treatment in the past 14 days. This product is contraindicated in patients with angle-closure glaucoma, urinary retention, severe hypertension, severe coronary artery disease and hyperthyroidism.

Clinical controlled studies of conventional doses have shown that, except for insomnia and dry mouth, the adverse reactions of compound loratadine sustained-release capsules are similar to those of placebo. Side effects seen between the two groups include headache and drowsiness. Very rare side effects include (in order of incidence) tension, dizziness, fatigue, nausea, abdominal discomfort, anorexia, thirst, palpitations, pharyngitis, rhinitis, acne, itching, rash, urticaria, joint pain, mental confusion, dysphonia, hyperkinesia, hypoesthesia, decreased libido, paresthesia, tremor, vertigo, flushing, postural hypotension, sweating, eye discomfort, earache, tinnitus, abnormal taste, excitement, apathy, depression, euphoria, nightmares, increased appetite, changes in bowel habits, indigestion, belching, hemorrhoids, tongue color changes, tongue discomfort, vomiting, transient abnormal liver function

Seal and store in a dry place. Validity period: tentatively 24 months

5mg/120mg (loratadine/pseudoephedrine sulfate)

Tentative 24 months

Venturpharm Pharmaceutical(Hainan)Limited.

• Founded in:

  2004-03-09

• Address:

  No. 279 Nanhai Avenue, Haikou City

• Tax NO.:

  914601007543894388

• Registered Funds:

  194.8706 million yuan

• Email:

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