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Ticlopidine Hydrochloride Capsules

Function and Efficacy

Antiplatelet aggregation drugs can inhibit platelet aggregation caused by various inducers such as ADP, collagen, thrombin, arachidonic acid and prostaglandin endoperoxides, and can inhibit platelet aggregation reactions induced by exogenous and endogenous ADP.

Ingredients

Main ingredients: Ticlopidine hydrochloride.

Name Description Content CAS NO. Manufacturer
Ticlopidine hydrochlorideIngredients

Antiplatelet aggregation drugs can inhibit platelet aggregation caused by various inducers such as ADP, collagen, thrombin, arachidonic acid and prostaglandin endoperoxides, and can inhibit platelet aggregation reactions induced by exogenous and endogenous ADP.

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53885-35-1 22

Appearance

Capsules, the contents are off-white granules.

Indication

Treat cardiovascular and cerebrovascular diseases caused by hyperplatelet aggregation.

Usage and Dosage

Oral administration: once a day, 0.25 g each time; take with meals to reduce gastrointestinal reactions.

Adverse Reactions

1 Occasionally, mild gastrointestinal reactions are seen; 2 Rare reactions include: nausea, diarrhea, rash, ecchymosis, gingival bleeding, leukopenia, granulocytopenia, cholestatic jaundice, and liver damage. All of the above adverse reactions disappear after drug withdrawal.

Precautions

1. Patients with recent bleeding; 2. Patients with recent ulcer disease with bleeding tendency or prolonged bleeding time; 3. Patients with allergies; 4. Patients with a history of leukopenia, thrombocytopenia, granulocytopenia or patients with aplastic anemia.

Drug Interactions

1. The combination of this product with any platelet aggregation inhibitor, thrombolytic agent, and drug that causes hypoprothrombinemia or thrombocytopenia may increase the risk of bleeding. If it is clinically necessary to use the drug together, close observation and laboratory monitoring should be performed; 2. When this product is used in combination with theophylline, theophylline blood concentration will increase and there is a risk of overdose because it reduces the clearance rate of the latter. Therefore, theophylline dosage should be adjusted during and after the use of this product, and theophylline blood concentration should be monitored when necessary; 3. When this product is used in combination with digoxin, the latter's blood concentration may decrease slightly (about 15%), but it generally does not affect the clinical efficacy of digoxin. (4) Occasionally, there are reports that this product reduces the blood concentration of cyclosporine, so the blood concentration of cyclosporine should be monitored regularly when the two are used in combination.

Storage

Keep away from light and store in a sealed container.

Packaging Specification

0.125g

Manufacturer

Qingdao Shengbang Pharmaceutical Co., Ltd.

  • Founded in:

    2010-11-02
  • Address:

    Qingdao Jiaozhou City Jiaodong Office Textile Industrial Park
  • Tax NO.:

    9137028156119444XE
  • Registered Funds:

    53.7038 million yuan
  • Email:

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