Trospium Chloride Capsules
Function and Efficacy
This product is a synthetic tropic acid derivative with four ammonium structures. It is a parasympathetic nerve blocker with similar effects to atropine. It mainly works by competitively binding with the endogenous neurotransmitter acetylcholine to the postsynaptic membrane M-receptor. It reduces the tension of the parasympathetic nerves and removes the smooth muscle spasms caused by the parasympathetic nerves in the organs controlled by the parasympathetic nerves. It also has a certain effect on the gastrointestinal tract, bile duct and urinary tract. This product has low lipid solubility and is not easy to pass through the blood-brain barrier, and will not produce side effects of the central nervous system. Acute and chronic toxicity experiments on two rodents showed that the observable side effects were caused by the increase in pharmacodynamic activity, rather than specific target organ toxicity, and there was no difference between sexes. There was no reproductive toxicity at the maximum tolerated dose, and in vivo and in vitro experiments showed no gene mutation and carcinogenic effects.
Ingredients
Trospium chloride. Its chemical name is: 3-dibenzyloxytropaphthyl-8-spiro-1-pyrrolidine chloride.
| Name | Description | Content | CAS NO. | Manufacturer |
|---|---|---|---|---|
| Trospium chlorideIngredients |
This product is a synthetic tropic acid derivative with four ammonium structures. It is a parasympathetic nerve blocker with similar effects to atropine. It mainly works by competitively binding with the endogenous neurotransmitter acetylcholine to the postsynaptic membrane M-receptor. It reduces the tension of the parasympathetic nerves and removes the smooth muscle spasms caused by the parasympathetic nerves in the organs controlled by the parasympathetic nerves. It also has a certain effect on the gastrointestinal tract, bile duct and urinary tract. This product has low fat solubility and is not easy to pass through the blood-brain barrier, and will not produce side effects on the central nervous system. More |
10405-02-4 | 23 |
Appearance
This product is in the form of capsules.
Indication
No data yet
Usage and Dosage
Oral administration, 2 times a day, 1 tablet each time (equivalent to 40 mg per day). Or as directed by a physician. The recommended dose for patients with severe renal insufficiency (creatinine clearance of 10-30 ml/min/1.73 m2) is 1 tablet per day or every other day (i.e. 20 mg per day or every other day). It should be taken with water on an empty stomach before meals, whole. The course of medication should be determined by the physician. And the physician shall decide whether to continue treatment during the regular follow-up of 3-6 months.
Adverse Reactions
Rare adverse reactions to this drug include dry mouth and constipation.
Precautions
1. It is contraindicated for patients who are allergic to this product and its ingredients. 2. It is contraindicated for patients with urinary retention, gastric retention and uncontrolled angle-closure glaucoma.
Special Population Medication
Precautions for children: Not yet clear. Precautions for pregnancy and lactation: Not yet clear. Precautions for the elderly: Not yet clear.
Drug Interactions
Drug interactions may occur if used with other drugs. Please consult your doctor or pharmacist for details.
Storage
seal.
Packaging Specification
20mg
Validity Period
24 months
Manufacturer
Shouguang Fukang Pharmaceutical Co., Ltd.
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Founded in:
1997-07-08 -
Address:
No. 666, Donghuan Road, Shouguang City, Shandong Province -
Tax NO.:
91370783613588951Q -
Registered Funds:
$156 million -
Website:
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Email: