Epinastine Hydrochloride Tablets

Pharmacological action: Epinastine is a histamine H1 receptor antagonist. This product has inhibitory effects on histamine, leukotriene C4, PAF, and 5-hydroxytryptamine, and can inhibit the release of histamine and slow-reacting substance A (SRS-A) chemical mediators. Due to the characteristics of its chemical structure, this product is difficult to pass through the blood-brain barrier and has a weak antagonistic effect on the H1 receptor of the central nervous system. Toxicological effects: Repeated administration: Rats were given the drug for 12 consecutive months at doses of 1, 6, and 60 mg/kg. The high-dose group animals showed a decrease in blood triglyceride levels. Monkeys were given the drug for 12 consecutive months at doses of 1, 8, and 60 mg/kg. The high-dose group animals had salivation, vomiting, and diarrhea. Reproductive toxicity: Rats were given epinastine for 5,

The main ingredient of this product is: Epinastine hydrochloride. Its chemical name is: 3-amino-9,13b-dihydro-1H-dibenzo[c,f]imidazo[1,5-a]azepine hydrochloride.

This product is a film-coated tablet, which appears white after removing the film coating.

This product is a histamine H1 receptor antagonist, suitable for the prevention and treatment of allergic rhinitis, urticaria, eczema, dermatitis, pruritus, prurigo, psoriasis vulgaris with itching and allergic bronchial asthma in adults.

1 Allergic rhinitis: Adults, take 10-20 mg (1-2 tablets) orally once a day. Or take according to the doctor's advice. 2 Urticaria, eczema, dermatitis, pruritus, psoriasis, bronchial asthma. Usually adults take 20 mg (2 tablets) orally once a day. Or take according to age and symptoms.

1. Allergy: When rash or occasional urticaria, itching, pruritic erythema occurs, the drug should be discontinued. 2. Mental and nervous system: Occasionally, drowsiness, fatigue, headache. 3. Digestive system: Gastrointestinal dysfunction or indigestion. 4. Liver: AST, ALT elevation can be seen, ALP, total cholesterol elevation and jaundice can be seen occasionally. 5. Kidney: Occasionally, proteinuria occurs. 6. Circulatory system: Palpitations. 7. Respiratory system: Occasionally, dyspnea, dyspnea, nasal congestion, etc. can occur. 8. Blood: Rarely, leukocytosis. If any abnormality occurs during treatment,

Patients who are allergic to any of the ingredients in this medicine are contraindicated.

Precautions for children: The safety of the drug for children has not been fully evaluated. Precautions for pregnancy and lactation: 1. Pregnancy: It is not recommended for pregnant women, especially in the first three months, or the drug can be used only after the doctor has made a judgment on the benefits and risks of the treatment. 2. Lactation: Experiments have shown that the drug can be transferred into breast milk, so it is not recommended for breastfeeding women to use it. If it must be used, breastfeeding should be terminated. Precautions for the elderly: Most elderly patients have impaired liver and kidney function. This product is mainly excreted from the kidneys. Adverse reactions and clinical symptoms (rash, thirst, stomach discomfort) should be observed regularly. When abnormalities occur, the dosage should be appropriately reduced (for example, 10 mg/day) or the drug should be stopped immediately.

No special circumstances were observed when it was used in combination with other drugs such as synthetic antibacterial drugs.

Seal and store in a dry place. Validity period: 24 months.

10mg

24 months

Beijing Jinchengtaier Pharmaceutical Co., Ltd.

• Founded in:

  2003-07-15

• Address:

  No. 9 Mintai Road, Beiwu Town, Shunyi District, Beijing (Science and Technology Innovation Functional Area)

• Tax NO.:

  911101057526411930

• Registered Funds:

  150 million yuan

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