Nifuratel Capsules

Pharmacological action Nifuratel is effective against bacteria, Trichomonas and Candida that cause female reproductive system infections. This product mainly inhibits the growth of bacteria by interfering with its enzyme system. It is difficult to pass through the placenta and has no teratogenic effect. Toxicological studies have shown that nifuratel has minimal toxicity in acute animal toxicology tests. The oral LD50 (lethal dose) of rabbits is 1500 times its therapeutic dose. No toxicity was found after rabbits were orally administered 450 mg/kg/day (equivalent to 20 times the therapeutic dose) for 47 days. In a 6-month long-term toxicity test, dogs took 10 times the therapeutic dose of humans orally every day without toxicity. Pregnant mice and rabbits took 100 mg/kg/day and 200 mg/kg/day orally, respectively, and no teratogenic or fertility changes occurred. No toxicity was observed after subcutaneous injection of 3000 times the therapeutic dose of this product.

The main ingredient of this product is nifuratel. Chemical name: 5-[(methylthio)methyl]-3-[(5-nitro-2-furylmethylene)amino]-2-oxazolidinone Chemical structure: 02NSCH Molecular formula: C, HN0S Molecular weight: 285.29

This product is a capsule, and the contents are yellow or yellow-green granules and powder.

1. Bacterial vaginosis, Trichomonas vaginitis, Candidal vulvovaginitis 2. Urinary tract infection 3. Gastrointestinal amebiasis and giardiasis

Vaginal infection: Take 0.2g each time (2 capsules of 0.1g, 1 capsule of 0.2g), 3 times a day for 7 consecutive days, take after meals, it is recommended that couples take it at the same time. Urinary tract infection: Adults: Take 0.6g-1.2g per day (6-12 capsules of 0.1g, 3-6 capsules of 0.2g), and take it for an average of 1-2 weeks (depending on the degree and nature of the infection). Children: 10-20mg/kg body weight/day, divided into 2 oral doses, and take it for an average of 1-2 weeks (depending on the degree and nature of the infection). Gastrointestinal amebiasis: Adults: Take 0.4g each time (4 capsules of 0.1g, 2 capsules of 0.2g), 3 times a day, for 10 consecutive days. Children: Take 10mg/kg body weight each time, 2 times a day, for 10 consecutive days. Gastrointestinal trichomoniasis: Adults: Take 0.4g each time (4 capsules of 0.1g, 2 capsules of 0.2g), 2-3 times a day: Oral administration for 7 consecutive days. Children: Take 15mg/kg each time, 2 times a day, for 10 consecutive days.

After marketing, the following adverse reactions of nifuratel oral preparations have been monitored (incidence is unknown): Skin and subcutaneous tissue diseases: rash, itching, urticaria, erythema, drug rash, maculopapular rash, skin swelling, hyperhidrosis; Gastrointestinal system diseases: nausea, vomiting, abdominal pain, diarrhea, abdominal discomfort, abdominal distension, dry mouth, bitter mouth, flatulence; Nervous system diseases: dizziness, vertigo, headache, drowsiness, insomnia, decreased sensation, numbness; Systemic diseases and administration site reactions: chest discomfort, fever, fatigue, pain, edema (face, mucous membrane, periphery), disulfiram-like reaction: Immune system diseases: allergic reaction, allergic-like reaction, anaphylactic shock; Reproductive system diseases: vulvovaginal itching, vulvovaginal swelling, vulvovaginal burning; Others: dyspnea, laryngeal edema, palpitations and flushing, joint pain, tinnitus, hematuria, urine discoloration, jaundice, increased transaminase, hemolytic anemia.

1. Patients with known allergy to nifuratel, nitrofurantoin or any of the ingredients in the prescription are contraindicated. 2. Patients with glucose-6-phosphate dehydrogenase deficiency (commonly known as favism) are contraindicated.

Precautions for children: Can be used. Precautions for pregnancy and lactation: Use with caution. Precautions for the elderly: Can be used.

Not yet clear.

seal.

(1) 0.1 g; (2) 0.2 g

24 months

Beijing Jinchengtaier Pharmaceutical Co., Ltd.

• Founded in:

  2003-07-15

• Address:

  No. 9 Mintai Road, Beiwu Town, Shunyi District, Beijing (Science and Technology Innovation Functional Area)

• Tax NO.:

  911101057526411930

• Registered Funds:

  150 million yuan

• Website:

  Log in to view

• Email:

  Log in to view