Thyroxine liothyronine eye drops

After the product is instilled into the eye, as the instillation period increases, T4 can slowly enter the eyeball. After one week, the T4 content in the aqueous humor increases significantly, and the lens absorbs T4 and deiodinates it in the tissue to become T3, thus producing physiological and therapeutic effects.

Main ingredients: Thyroid powder extract.

This product is a suspension of fine particles. After standing, the fine particles sink. After shaking, it becomes a milky white or slightly yellow suspension. [Indications/Functions] Used for the treatment of early and immature senile cortical cataracts. [Specifications] 3mg:3ml [Usage and Dosage] Shake well before use, 1 drop each time, 4 times a day; long-term users 1 drop each time, 1-2 times a day or follow the doctor's advice. [Adverse Reactions] 1. No adverse reactions have been found at the therapeutic dose of this product. 2. Very few patients may develop diffuse superficial keratitis, conjunctival congestion, irritation, itching and other symptoms. If the above symptoms occur, the medication should be stopped and symptomatic treatment should be given. 3. For special patients who need long-term medication, if you find that your food intake has increased, your body temperature has increased, and your weight has decreased significantly, please find out the cause before taking the medication. 4. Studies have shown that oral thyroid hormone overdose may cause tachycardia, palpitations, angina, arrhythmia, headache, nervousness, excitement, restlessness, insomnia, skeletal muscle spasm, muscle weakness, sweating, flushing, heat intolerance, diarrhea, vomiting, weight loss, etc., which may gradually disappear after reducing the dosage or stopping the drug. This product is an eye drop. There is no research data to prove that overdose of this product can cause the above adverse reactions. However, care should be taken not to overdose this product. [Contraindications] 1. It is contraindicated for those who are allergic to thyroid hormones. 2. It is contraindicated for patients with hyperthyroidism. 3. It is contraindicated for patients with tachycardia and intraocular hemorrhage. [Precautions] 1. Allergy test method: For the first use, drop one drop of this product in one eye. If there is no adverse reaction within 24 hours, it can be used. 2. It is for eye drops only. When using this product, please note: (1) Only drop 1 drop each time to prevent the drug from flowing into the nasal cavity. (2) Avoid contact between the dropper and the eye or other objects to prevent contamination of the drug. (3) After use, cover the bottle cap tightly and store in a cool place away from light to prevent deterioration. 3. After the treatment with this product is effective, if the drug is stopped for too long, the condition may continue to develop. Except for seriously ill patients, this product is still effective when used again for treatment. Please read the instructions carefully and use it according to the doctor's advice. [Drug use in children] Forbidden. [Drug use in elderly patients] No special effects. [Drug use in pregnant and lactating women] Forbidden. [Drug Interactions] [Drug Overdose] This product was administered to domestic dogs at 48 times (0.24mg/Kg/d) and 96 times (0.48mg/Kg/d) the amount of eye drops used in human clinical practice, for 6 days a week for 26 consecutive weeks. The results showed that: 1. After administration, the weight gain of the animals slowed down significantly, the body became thinner, and the food intake increased significantly; the animals' eyes were slightly irritated. 2. Hematological indicators: The proportion of lymphocytes (LY%) increased significantly; serum biochemical examination showed that cholesterol (CHOL) decreased, aspartate aminotransferase (AST) and alanine aminotransferase (ALT) increased significantly; T3 and T4 increased significantly, which was significantly different from the blank control. After drug withdrawal, LY%, CHOL, AST, ALT, and T4 returned to normal, while T3 decreased significantly. 3. No abnormalities were found in the general behavior and urine routine examination of the animals. Gross anatomy showed no obvious lesions in various organs. [Pharmacology and Toxicology] After the product is instilled into the eye, T4 can slowly enter the eyeball as the instillation date is extended. After one week, the content of T4 in the anterior chamber water increases significantly, and the lens absorbs T4 and then deiodinates in the tissue to become T3, thus producing physiological and therapeutic effects. [Pharmacokinetics] This product has a pharmacological effect against experimental selenium cataracts. It can increase the overall transparency of the lens, reduce nuclear opacity, reduce the degree of damage to the lens fibers, and reduce the degree of damage to the potassium-sodium adenosine triphosphatase containing sulfhydryl (-SH) in the lens epithelial cells. The human clinical dosage of this product (5mg/Kg and 15mg/Kg, im) has no effect on the spontaneous activity of mice, and has no significant effect on the respiratory amplitude, systolic blood pressure, diastolic blood pressure and electrocardiogram ST segment of anesthetized dogs. 20 times the human clinical dosage has no effect on the dog's arterial blood pressure, electrocardiogram, heart rate, nor does it affect the dog's normal respiratory rate. [Storage] Sealed. [Packaging] Plastic bottle; 3ml. [Validity period] 36 months [Implementation standard] [Approval number] National medicine standard H20050130 [Manufacturer] Wuhan Wujing Pharmaceutical Co., Ltd.

Treat senile cataracts.

Shake well before use, 1 drop each time, 4 times a day; for long-term users, 1 drop each time, 1-2 times a day or as directed by a doctor.

1. No adverse reactions have been found at the therapeutic dose of this product. 2. Very few patients may experience diffuse superficial keratitis, conjunctival congestion, irritation, itching and other symptoms. If the above symptoms occur, the medication should be stopped and symptomatic treatment should be given. 3. For special patients who need long-term medication, if the food intake increases, the body temperature rises, and the weight is significantly reduced, please find out the cause before taking the medication. 4. Studies have shown that excessive oral thyroid hormone may cause tachycardia, palpitations, angina pectoris, arrhythmia, headache, nervousness, excitement, restlessness, insomnia, skeletal muscle spasm, muscle weakness, sweating, flushing, heat intolerance, diarrhea, vomiting, weight loss, etc., which may gradually disappear after reducing the dose or stopping the medication. This product is an eye drop, and there is no research data to prove that excessive use of this product can cause the above adverse reactions. However, care should be taken not to overdose this product.

1. Patients who are allergic to thyroid hormones are prohibited from using this product. 2. Patients with hyperthyroidism are prohibited from using this product. 3. Patients with tachycardia or intraocular hemorrhage are prohibited from using this product.

Precautions for children: Do not use. Precautions for pregnancy and lactation: Do not use. Precautions for the elderly: No special effects.

drugInteractions

seal.

3ml:3mg thyroid powder extract

36 months

Wuhan Wujing Pharmaceutical Co., Ltd.

• Founded in:

  2001-12-30

• Address:

  No. 2, Jinyinhu South Third Street, Jinyinhu Office, Dongxihu District, Wuhan

• Tax NO.:

  91420000177568347U

• Registered Funds:

  30 million yuan

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