Sodium Fusidate for Injection
Function and Efficacy
Sodium fusidate produces bactericidal effects by inhibiting bacterial protein synthesis and has a strong antibacterial effect on a series of Gram-positive bacteria. Staphylococci, including strains resistant to penicillin, methicillin and other antibiotics, are highly sensitive to this product. There is no cross-resistance between sodium fusidate and other antibacterial drugs used clinically. Sodium fusidate has extremely low toxicity and no cross-allergy with other antibacterial drugs used clinically. Therefore, it can be used to treat patients who are contraindicated to other antibiotics, such as those who are allergic to penicillin or other antibiotics. When long-term medication is required due to severe or deep infections, it is recommended that sodium fusidate be used in combination with other anti-staphylococcal drugs to reduce the development of drug resistance. Sodium fusidate can be used in combination with penicillinase-resistant penicillins, cephalosporins, erythromycin, aminoglycosides, lincomycin, rifampicin or vancomycin, and an additive or synergistic effect can be obtained.
Ingredients
The main ingredient of this product is sodium fusidate.
| Name | Description | Content | CAS NO. | Manufacturer |
|---|---|---|---|---|
| Sodium fusidateIngredients |
It produces bactericidal effects by inhibiting bacterial protein synthesis and has a strong antibacterial effect on a series of Gram-positive bacteria. Staphylococci (including strains resistant to penicillin, methicillin and other antibiotics) are highly sensitive to this product. There is no cross-resistance and cross-allergy with other antibacterial drugs used in clinical practice, and it can be used to treat patients who are contraindicated to other antibiotics. It can be used in combination with a variety of anti-staphylococcal drugs to reduce drug resistance and obtain additive or synergistic effects. More |
751-94-0 | 12 |
Appearance
This product is white crystalline powder and the solvent is colorless clear liquid.
Indication
It is mainly used to treat various infections caused by various sensitive bacteria, especially staphylococci, such as osteomyelitis, sepsis, endocarditis, recurrent cystic fibrosis, pneumonia, skin and soft tissue infections, surgical and traumatic infections, etc.
Usage and Dosage
Suitable for patients who are not suitable for oral administration or have poor gastrointestinal absorption. Adults 500mg (1 bottle)/time, 3 times a day. The total daily dose should not exceed 2g. Children and infants 20mg/kg body weight/day, divided into 3 doses.
Adverse Reactions
Intravenous injection of this product may cause thrombophlebitis and venous spasm. Reversible increase of transaminases has been reported when taking 1.5-3 grams per day. It has been reported that some patients developed reversible jaundice after taking the drug, which is mainly seen in large-dose intravenous administration, especially in patients with severe Staphylococcus aureus bacteremia. If jaundice persists, the drug should be discontinued, and serum bilirubin will return to normal. Reports of allergic reactions are very rare.
Precautions
People who are allergic to sodium fusidate should not use this product.
Drug Interactions
There are occasional reports that this product can increase the anticoagulant effect of coumarin drugs.
Storage
Store at room temperature (15-25℃).
Packaging Specification
0.125g, prepared with 10ml sterile buffer solution
Manufacturer
Chengdu Tiantai Mountain Pharmaceutical Co., Ltd.
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Founded in:
2000-09-29 -
Address:
No. 88 Tianxing Avenue, Qionglai City, Sichuan Province -
Tax NO.:
915101832024104543 -
Registered Funds:
75 million yuan -
Website:
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Email: