Amoxicillin Granules
Function and Efficacy
Amoxicillin is a penicillin antibiotic that has good antibacterial activity against Streptococcus such as Streptococcus pneumoniae and hemolytic Streptococcus, aerobic Gram-positive cocci such as non-penicillinase-producing Staphylococci and Enterococcus faecalis, aerobic Gram-negative bacteria such as Escherichia coli, Proteus mirabilis, Salmonella, Haemophilus influenzae, Neisseria gonorrhoeae, and Helicobacter pylori. Amoxicillin exerts its bactericidal effect by inhibiting the synthesis of bacterial cell walls, which can quickly dissolve and rupture bacteria into spherical bodies.
Ingredients
The main ingredient of this product is amoxicillin.
| Name | Description | Content | CAS NO. | Manufacturer |
|---|---|---|---|---|
| AmoxicillinIngredients |
Amoxicillin is a penicillin antibiotic that has good antibacterial activity against Streptococcus such as Streptococcus pneumoniae and hemolytic Streptococcus, aerobic Gram-positive cocci such as non-penicillinase-producing Staphylococci and Enterococcus faecalis, aerobic Gram-negative bacteria such as Escherichia coli, Proteus mirabilis, Salmonella, Haemophilus influenzae, Neisseria gonorrhoeae, and Helicobacter pylori. Amoxicillin exerts its bactericidal effect by inhibiting the synthesis of bacterial cell walls, which can quickly dissolve and rupture bacteria into spherical bodies. More |
26787-78-0 | 30 |
Appearance
This product is a granule, the contents are white, off-white or light yellow granules and powder, with a fragrant smell and sweet taste.
Indication
1. Otitis media, sinusitis, pharyngitis, tonsillitis and other upper respiratory tract infections caused by hemolytic streptococci, pneumococcus, staphylococcus or Haemophilus influenzae. 2. Urogenital tract infections caused by Escherichia coli, Proteus mirabilis or Enterococcus faecalis. 3. Skin and soft tissue infections caused by hemolytic streptococci, staphylococcus or Escherichia coli. 4. Acute bronchitis, pneumonia and other lower respiratory tract infections caused by hemolytic streptococci, pneumococcus, staphylococcus or Haemophilus influenzae. 5. Acute simple gonorrhea. 6. This product can also be used to treat typhoid fever, typhoid carriers and leptospirosis; amoxicillin can also be used in combination with clarithromycin and lansoprazole to eradicate gastric and duodenal Helicobacter pylori and reduce the recurrence rate of peptic ulcers.
Usage and Dosage
Oral. Tear open the small bag, pour the powder into an appropriate amount of cold boiled water, shake well, and then take it. Children: Daily dose is 20-40mg/kg based on body weight, once every 8 hours. Newborns and premature infants take 50mg orally each time, and infants under 3 months old take 30mg/kg based on body weight. Amoxicillin granules reference dosage for children 125mg/bag/time 250mg/bag/time Daily dosage for infants under 3 months old 0.4 bag 0.2 bag 3 times a day or as prescribed by a doctor Under one year old 0.5 bag 0.25 bag 3 times a day or as prescribed by a doctor 1-3 years old 1 bag 1/2 bag 3 times a day or as prescribed by a doctor 3-5 years old 1.5 bags 3/4 bags 3 times a day or as prescribed by a doctor 5-10 years old 2 bags 1 bag 3 times a day or as prescribed by a doctor 10 years old and above 2-3 bags 1-1.5 bags 3 times a day or as prescribed by a doctor
Adverse Reactions
1. Gastrointestinal reactions such as nausea, vomiting, diarrhea and pseudomembranous colitis. 2. Allergic reactions such as rash, drug fever and asthma. 3. Anemia, thrombocytopenia, eosinophilia, etc. 4. Serum aminotransferase may be slightly increased. 5. Superinfection caused by Candida or drug-resistant bacteria. 6. Occasionally, central nervous system symptoms such as excitement, anxiety, insomnia, dizziness and abnormal behavior may occur.
Precautions
1. It is contraindicated for patients allergic to penicillin. 2. A penicillin sodium skin test must be performed before use, and it is contraindicated for those with a positive reaction.
Special Population Medication
Precautions for children: This product is suitable for children. Precautions for pregnancy and lactation: Animal reproduction studies have shown that amoxicillin at 10 times the human dose did not damage the fertility and fetuses of rats and mice. However, there is still a lack of sufficient controlled studies in humans. Given that animal reproduction studies cannot fully predict human reactions, pregnant women should only use this product when it is necessary. Since a small amount of amoxicillin can be secreted in breast milk, it may cause allergies in infants after being taken by nursing mothers. Precautions for the elderly: The dose may need to be adjusted for the elderly and those with severe renal impairment.
Drug Interactions
1. Probenecid competitively reduces the renal tubular secretion of this product. The simultaneous use of the two can cause an increase in the blood concentration of amoxicillin and a prolonged half-life. 2. Chloramphenicol, macrolides, sulfonamides and tetracyclines interfere with the antibacterial effect of amoxicillin in vitro, but the clinical significance is unclear.
Storage
Keep in a light-proof and airtight container.
Packaging Specification
0.125g (calculated as C16H19N305 tablets)
Validity Period
24 months.
Manufacturer
Hainan Simcere Pharmaceutical Co., Ltd.
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Founded in:
1993-04-28 -
Address:
No. 2, Yaogu 3rd Road, Xiuying District, Haikou City, Hainan Province -
Tax NO.:
91460000201357380E -
Registered Funds:
221.1109 million yuan -
Website:
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Email: