Compound Amino Acid Injection for Children (19AA-Ⅰ)
Function and Efficacy
1. It contains a relatively high concentration of essential amino acids for children, including histidine, tyrosine, and cysteine. 2. Phenylalanine can be metabolized into tyrosine, but due to the imperfect liver enzyme system in children, metabolism cannot be carried out effectively. Therefore, the concentration balance in plasma is maintained by increasing the amount of tyrosine and reducing phenylalanine. 3. Methionine is the precursor of cysteine and taurine. Also due to the imperfect liver enzyme system in children, taurine is added and an appropriate amount of cysteine is supplemented according to the physical condition of the child during use. Therefore, the methionine content of this product is relatively low. 4. The glycine content is relatively low to prevent high blood ammonia. 5. It contains an appropriate amount of glutamic acid and aspartic acid because the content is relatively high in human milk. 6. Taurine is a metabolite of methionine and cysteine. It is abundant in human milk and has the functions of protecting cell membranes, promoting brain development, maintaining normal retinal function, preventing cholestasis, and enhancing myocardial cell function.
Ingredients
Each 1000ml contains (unit: g): L-isoleucine 4.9g, L-leucine 8.4g, L-lysine 4.9g, L-methionine 2.0g, L-phenylalanine 2.9g, L-threonine 2.5g, L-tryptophan 1.2g, L-valine 4.7g, L-cysteine HCL.H2O0.2g, L-histidine 2.9g, L-tyrosine 1.4g, L-alanine 3.2g, L-arginine 7.3g, L-proline 4.1g, L-serine 2.3g, glycine
| Name | Description | Content | CAS NO. | Manufacturer |
|---|---|---|---|---|
| L-IsoleucineIngredients |
Essential amino acids for children More |
73-32-5 | 19 | |
| L-LeucineIngredients |
Essential amino acids for children More |
61-90-5 | 10 | |
| L-LysineIngredients |
Essential amino acids for children More |
6899-06-5 | 0 | |
| L-MethionineIngredients |
Essential amino acids for children, precursor of cysteine and taurine More |
63-68-3 | 12 | |
| L-PhenylalanineIngredients |
Can be metabolized into tyrosine, but the metabolism is incomplete in children, so the content needs to be adjusted to balance the plasma concentration More |
3617-44-5 | 0 | |
| L-ThreonineIngredients |
Essential amino acids for children More |
72-19-5 | 13 | |
| L-TryptophanIngredients |
Essential amino acids for children More |
73-22-3 | 12 | |
| L-ValineIngredients |
Essential amino acids for children More |
72-18-4 | 9 | |
| L-HistidineIngredients |
Essential amino acids for children More |
71-00-1 | 20 | |
| L-TyrosineIngredients |
Maintain plasma concentration balance. Children with impaired liver enzyme system need additional supplementation More |
60-18-4 | 7 | |
| L-AlanineIngredients |
Nonessential amino acids More |
56-41-7 | 8 | |
| L(+)-ArginineIngredients |
Nonessential amino acids More |
74-79-3 | 25 | |
| L-ProlineIngredients |
Nonessential amino acids More |
147-85-3 | 13 | |
| L-SerineIngredients |
Nonessential amino acids More |
56-45-1 | 9 | |
| GlycineIngredients |
Lower levels to prevent high blood ammonia levels More |
56-40-6 | 27 | |
| L-Glutamic acidIngredients |
The content in human milk is high, add appropriate amount More |
56-86-0 | 17 | |
| L-ASPARTIC ACIDIngredients |
The content in human milk is high, add appropriate amount More |
6899-03-2 | 18 | |
| TaurineIngredients |
Metabolites of methionine and cysteine protect cell membranes, promote brain development, maintain normal retinal function, prevent cholestasis and enhance myocardial cell function More |
107-35-7 | 17 |
Appearance
This product is a colorless or almost colorless clear liquid.
Indication
This product is an intravenous parenteral nutrition infusion. It is used for: 1. Premature infants, low-weight infants and newborns who cannot orally take in protein or who do not take enough protein due to various causes. 2. Various traumas: such as burns, trauma and post-operative children with high metabolic states. 3. Children with various acute and chronic malnutrition who cannot orally take food or do not take enough food: such as necrotizing enterocolitis, acute necrotizing pancreatitis, chemotherapy drug reactions, etc.
Usage and Dosage
1. Use central venous catheter or peripheral intravenous administration, but both require slow drip. 2. Use 20-35 ml per kilogram of body weight per day or follow the doctor's advice. 3. During drip, each gram of nitrogen should also provide 150-200 kcal of non-protein calories (glucose, fat emulsion), plus vitamins, trace elements, etc.
Adverse Reactions
Infusing this product too quickly may cause adverse reactions such as nausea, vomiting, palpitations, and fever.
Precautions
It is contraindicated for patients with amino acid metabolism disorders and azotemia.
Special Population Medication
Precautions for children: This experiment has not been conducted and there is no reliable reference. Precautions for pregnancy and lactation: This experiment has not been conducted and there is no reliable reference. Precautions for the elderly: This experiment has not been conducted and there is no reliable reference.
Drug Interactions
Not yet clear.
Storage
Closed, placed in a cool dark place.
Packaging Specification
20ml:1.2g (total amino acids)
Validity Period
24 months
Manufacturer
China Resources Double-Crane Pharmaceutical Co., Ltd.
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Founded in:
1997-05-16 -
Address:
No. 1, Lize East 2nd Road, Wangjing, Chaoyang District, Beijing -
Tax NO.:
91110000633796475U -
Registered Funds:
1,038,836,522 yuan -
Website:
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Email: