Diclofenac Sodium Lidocaine Injection

The main ingredient is diclofenac sodium, which is a non-steroidal active substance. Its main mechanism of action is to inhibit cyclooxygenase and thus reduce the biosynthesis of prostaglandins. It has anti-rheumatic, anti-inflammatory, analgesic and antipyretic effects. It also has analgesic effects for moderate to severe pain. It is particularly suitable for the following diseases: the first treatment of inflammatory and degenerative rheumatic diseases, the treatment of pain in non-rheumatic inflammation, and the analgesic effect of the drug will take effect within 15 to 30 minutes.

This product is a compound preparation, its components are: diclofenac sodium and lidocaine hydrochloride

This product is a colorless to slightly yellow clear liquid.

Severe inflammatory or degenerative rheumatic diseases: rheumatoid arthritis, ankylosing spondylitis, arthritis, spondyloarthropathies, painful spondylosis, extra-articular rheumatic diseases. Acute gout attacks. Renal and biliary colic. Pain, inflammation and swelling after injury or surgery.

Inject deeply in the upper back of the buttocks, one injection at a time, once a day. For severe patients, two injections can be given daily, with a few hours between the two injections (change the injection site). The maximum daily dose is 150 mg. The course of treatment should not exceed 2 days. If it is still necessary, diclofenac sodium enteric-coated tablets or suppositories can be used as maintenance treatment.

Gastrointestinal Infrequently: epigastric pain, other gastrointestinal symptoms such as nausea, vomiting, diarrhea, abdominal cramps, dyspepsia, bloating, anorexia, anorexia. Rarely: gastrointestinal bleeding (hematemesis, tarry stools, and blood in the stool), peptic ulcer with or without bleeding or perforation. Isolated cases: lower abdominal symptoms (e.g., exacerbation of nonspecific hemorrhagic ulcerative colitis or regional enteritis), stomatitis, glossitis, esophageal injury, diaphragmatic intestinal stenosis, constipation, pancreatitis, and hemorrhoidal attacks. Central and peripheral nervous system Infrequently: headache, dizziness, lightheadedness. Rarely: fatigue. Isolated cases: sensory disturbances, including paresthesias, memory impairment, disorientation, insomnia, irritability, convulsions, depression, anxiety, phobia, tremor, psychotic reactions, aseptic meningitis

Patients with stomach and duodenum. Patients who are allergic to the active ingredients of Olphen or other contained medicinal ingredients. Patients with attacks are contraindicated. Patients who have developed urticaria and acute rhinitis after using acetylsalicylic acid or other drugs that inhibit prostaglandin synthase are contraindicated.

When lithium and digoxin are used together, the plasma concentration of lithium and digoxin will be increased. Like other nonsteroidal anti-inflammatory drugs, Orfen will reduce the efficacy of diuretics. When used in combination with potassium-sparing diuretics, it will cause hyperkalemia, so the serum potassium concentration should be carefully observed when using it. The combination of nonsteroidal anti-inflammatory drugs with different nonsteroidal anti-inflammatory drugs or glucocorticoids will increase the occurrence of adverse reactions. Clinical studies on anticoagulants have shown that diclofenac does not affect the effect of anticoagulants, but out of caution, when anticoagulants are used in combination with diclofenac, it is recommended to use laboratory index controls to detect the desired anticoagulant effect. Like other nonsteroidal anti-inflammatory drugs, large doses of diclofenac (200mg) have a reversible inhibitory effect on platelet aggregation in the short term. It can be used in combination with diabetes drugs without affecting the therapeutic effect of the therapeutic drugs. However, there are also some cases where hypoglycemia and hyperglycemia occurred after the use of diclofenac, so when used in combination with diclofenac. Treatment should be adjusted according to the condition. The effect of cyclosporine nonsteroidal anti-inflammatory drugs on renal prostaglandins can increase the renal toxicity of cyclosporine. Quinolone antibiotics There are case reports that quinolone antibiotics may cause convulsions when used in combination with nonsteroidal anti-inflammatory drugs.

Keep away from light and store in airtight storage.

2ml: Diclofenac sodium 75mg and lidocaine hydrochloride (calculated as lidocaine) 20mg

24 months

Cisen Pharmaceutical Co., Ltd.

• Founded in:

  1998-11-06

• Address:

  Tongji Science and Technology Industrial Park, Jining High-tech Zone

• Tax NO.:

  91370800706117999P

• Registered Funds:

  452,754,129 yuan

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