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Acyclovir granules

Function and Efficacy

Acyclovir has an inhibitory effect on herpes simplex virus, varicella zoster virus, cytomegalovirus, etc. in vitro. The drug is easily taken up by herpes simplex virus, then phosphorylated into triphosphate, which inhibits viral replication in two ways: interfering with viral DNA polymerase and inhibiting viral replication; under the action of DNA polymerase, it binds to the growing DNA chain, causing the extension of the DNA chain to be interrupted.

Ingredients

Main ingredient: Acyclovir

Name Description Content CAS NO. Manufacturer
AcyclovirIngredients

In vitro, it has an inhibitory effect on herpes simplex virus, varicella zoster virus, cytomegalovirus, etc. The drug is easily taken up by herpes simplex virus, then phosphorylated into triphosphate, which inhibits viral replication in two ways: interfering with viral DNA polymerase and inhibiting viral replication; under the action of DNA polymerase, it binds to the growing DNA chain, causing the extension of the DNA chain to be interrupted.

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Appearance

This product is white or off-white soluble granules, odorless, slightly sweet taste.

Indication

1. Herpes simplex virus infection: used for initial and recurrent cases of genital herpes virus infection; for recurrent cases, this product is used for prevention. 2. Herpes zoster: used for the treatment of herpes zoster in people with normal immune function and mild cases in people with immunodeficiency. 3. Used for the treatment of chickenpox in people with immunodeficiency.

Usage and Dosage

Oral administration, adults take one bag each time, 5 times a day (once every 4 hours during the day), one course of treatment is 5-10 days or as directed by a doctor.

Adverse Reactions

1. Oral administration rarely causes skin itching, and long-term administration occasionally causes menstrual disorders. 2. Long-term oral administration of this product may cause joint pain, diarrhea, headache, nausea, vomiting, dizziness, thirst, leukocytopenia, proteinuria and mild increase in urea nitrogen (more common than short-term medication). Long-term medication may cause acne and insomnia, and short-term medication may cause loss of appetite, but both are rare. If the above symptoms persist or are obvious, attention should be paid.

Precautions

It is contraindicated for people who are allergic to this product and pregnant women.

Special Population Medication

Precautions for children: 1. No special adverse reactions were found in children. 2. The dosage for children under two years old has not been determined. Precautions for pregnancy and lactation: 1. Fertility and pregnant women: No testicular atrophy or decreased sperm count was observed in humans taking 400 mg and 1000 mg orally daily for 6 consecutive months, and the drug can pass the placenta. 2. Breastfeeding mothers: The concentration of the drug in breast milk is 0.6-4.1 times the blood drug concentration, but no abnormalities were found in infants. Precautions for the elderly: Due to the decline of physiological renal function in the elderly, the dosage and medication interval of this product need to be adjusted.

Drug Interactions

Concomitant use with zidovudine may cause nephrotoxicity, manifested by profound lethargy and fatigue.

Storage

Keep sealed.

Packaging Specification

0.2g

Validity Period

24 months.

Manufacturer

Hangzhou Yipin Xinwufeng Pharmaceutical Co., Ltd.

  • Founded in:

    1995-08-10
  • Address:

    Sujia Village, Nanyuan Street, Linping District, Hangzhou City, Zhejiang Province (Guanbao Bridge)
  • Tax NO.:

    91330110143907988W
  • Registered Funds:

    55 million yuan
  • Website:

  • Email:

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