Roxithromycin Tablets

This product is a semi-synthetic 14-membered macrolide antibiotic. Its antibacterial spectrum and antibacterial effect are basically similar to those of erythromycin. Its effect on Gram-positive bacteria is slightly worse than that of erythromycin, and its effect on Legionella pneumophila is stronger than that of erythromycin. Its antimicrobial effect on Chlamydia pneumoniae, Mycoplasma pneumoniae, and Ureaplasma urealyticum is similar to or slightly stronger than that of erythromycin. This product can penetrate the bacterial cell membrane and reversibly bind to the 50S subunit of the bacterial ribosome near the donor (P position), blocking the transfer RNA (t-RNA) from binding to the P position, and also blocking the transfer of the polypeptide chain from the acceptor position (A position) to the P position, thereby inhibiting bacterial protein synthesis.

Ingredients Roxithromycin [Chemical name] 9-{0-[(2-methoxyethoxy)-methyl]oxime}erythromycin

Film-coated tablets appear white after removing the film coating.

1 Suitable for the following infections caused by sensitive strains: (1) upper respiratory tract infections; (2) lower respiratory tract infections; (3) ear, nose and throat infections; (4) genital infections (except gonococcal infections); (5) skin and soft tissue infections. 2 Can also be used for mycoplasma pneumonia, Chlamydia trachomatis infections and Legionnaires' disease.

Oral administration: Adults: 0.15g at a time, twice a day, or as directed by a doctor.

The main adverse reactions are gastrointestinal reactions such as abdominal pain, diarrhea, nausea, and vomiting, but the incidence is significantly lower than that of erythromycin.

Patients who are allergic to this product, erythromycin or other macrolide drugs are contraindicated.

Precautions for children: Not clear. Precautions for pregnancy and lactation: Use with caution in pregnant and lactating women. A dosage of less than 0.05% is excreted into breast milk. Although there are reports that it has little effect on infants, it is still necessary to consider whether to stop breastfeeding. Precautions for the elderly: If there is no significant change in pharmacokinetics in the elderly, there is no need to adjust the dose.

1. This product cannot be used in combination with ergotamine, dihydroergotamine, bromocriptine, terfenadine, ketoconazole and cisapride. 2. It has little effect on the metabolism of aminophylline and has little effect on carbamazepine, warfarin, ranitidine and other antacids.

Sealed, store in a dry place.

150 mg (150,000 units)

24 months

Jiangxi Huiren Pharmaceutical Co., Ltd.

• Founded in:

  2002-04-03

• Address:

  No. 1266, Huiren Avenue, Xiaolan Economic and Technological Development Zone, Nanchang, Jiangxi

• Tax NO.:

  91360121736373627B

• Registered Funds:

  450 million yuan

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