Diclofenac Sodium Enteric-Coated Tablets

Pharmacological action: Diclofenac is a non-steroidal anti-inflammatory analgesic derived from phenylacetic acid. Its mechanism of action is to inhibit the activity of cyclooxygenase, thereby blocking the conversion of arachidonic acid into prostaglandins. At the same time, it can also promote the combination of arachidonic acid and triglycerides (triacylglycerols), reduce the concentration of free arachidonic acid in cells, and indirectly inhibit the synthesis of leukotrienes. Diclofenac is one of the stronger non-steroidal anti-inflammatory drugs. Its inhibitory effect on prostaglandin synthesis is stronger than that of aspirin and indomethacin. Non-clinical toxicology studies: Rats were given oral diclofenac sodium at a daily dose of 2 mg/kg, and no increase in tumor incidence was found in long-term observation. In a two-year study on mice, 2 mg/kg of the drug was used daily, and no tumor susceptibility was observed. Various mutation studies have not found that diclofenac

The main ingredient of this product is diclofenac. Its chemical name is [o-(2,6-dichloroaniline)]phenylacetic acid.

This product is enteric-coated tablets, which appear white after removing the enteric coating.

1 Acute and chronic rheumatoid arthritis, acute and chronic ankylosing spondylitis, osteoarthritis. 2 Periarthritis of shoulder, bursitis, tendinitis and tenosynovitis. 3 Low back pain, sprain, strain and other soft tissue injuries. 4 Acute gout. 5 Dysmenorrhea or adnexitis, toothache and postoperative pain. 6 Pain and inflammation after trauma, such as sprain, muscle strain, etc.; 7 Severe infectious pain and inflammation of the ear, nose and throat (such as tonsillitis, otitis, sinusitis, etc.), anti-infective drugs should be used at the same time.

Oral administration: once a day, or 1 to 2 times a day, or as directed by a doctor, after meals.

1. May cause gastrointestinal reactions such as headache and abdominal pain, constipation, diarrhea, stomach burning sensation, nausea, and indigestion. 2. Occasionally, headache, dizziness, and vertigo may occur. Serum glutamate oxaloacetate aminotransferase (GOT) and serum glutamate pyruvate aminotransferase (GPT) may increase. 3. Rarely, renal function may decrease, which may lead to water and sodium retention, manifested by low urine volume, facial edema, and sudden weight gain. Very rarely, it may cause arrhythmia, tinnitus, etc. 4. Rare: rash, gastrointestinal bleeding, peptic ulcer, hematemesis, melena, gastrointestinal ulcer, perforation, bloody diarrhea, drowsiness, and allergic reactions such as asthma, hepatitis, and edema. 5. May cause bone marrow suppression or aggravate it.

1. Patients with allergic reactions, asthma, urticaria or other allergic reactions to this product, aspirin or other non-steroidal anti-inflammatory drugs. 2. Patients with peptic ulcers.

Precautions for children: Children under 16 years old should not take this medicine. Precautions for pregnancy and lactation: Pregnant and lactating women should not take this medicine. Precautions for the elderly: This product may induce or aggravate gastrointestinal bleeding, ulcers and perforations in the elderly. Use with caution in elderly patients who are taking diuretics or have extracellular fluid loss.

Diclofenac can increase the plasma concentration of digoxin and lithium-containing preparations and reduce the renal excretion of methotrexate. Therefore, special caution should be exercised when used in combination with these drugs.

Keep away from light, tightly closed and in a dry place.

25mg

24 months

Diaoyutai Medicine Group Ji Lin Tian Qiang Drugs Manufacture Limited Liability Company

• Founded in:

  1999-09-01

• Address:

  No. 309 Renmin Street, Liuhe Town, Liuhe County

• Tax NO.:

  91220501125575596F

• Registered Funds:

  50 million yuan

• Website:

  Log in to view

• Email:

  Log in to view