Ribavirin Injection

Antiviral drug. It has the effect of inhibiting the growth of many viruses such as respiratory syncytial virus, influenza virus, hepatitis A virus, adenovirus, etc. in vitro, and its mechanism is not fully understood. This product does not change the adsorption, invasion and uncoating of viruses, nor does it induce the production of interferon. After entering the virus-infected cells, the drug is rapidly phosphorylated, and its product acts as a competitive inhibitor of viral synthase, inhibiting inosine monophosphate dehydrogenase, influenza virus RNA polymerase and mRNA guanosine transferase, thereby causing a decrease in intracellular guanosine triphosphate, impairing viral RNA and protein synthesis, and inhibiting viral replication and transmission. It may also have an immune effect and neutralizing antibody effect on respiratory syncytial virus.

The main ingredient of this product is ribavirin, whose chemical name is 1-beta;-D-ribofuranosyl-1H-1,2,4-triazole-3-carboxamide.

This product is a colorless clear liquid

It is mainly used for viral pneumonia and bronchitis caused by respiratory syncytial virus (RSV). It is used for the prevention and treatment of epidemic hemorrhagic fever and Lassa fever. The early application of this product in the fever stage can shorten the fever period, alleviate kidney and blood vessel damage and poisoning symptoms. Topical application can treat herpes simplex virus keratitis.

Intravenous drip: 500-1000 mg per day for adults, divided into 2 doses, each drip for more than 20 minutes. The course of treatment is 3-7 days. In the treatment of severe cases such as Lassa fever and epidemic hemorrhagic fever, the first dose for adults is 2 g, followed by 0.5-1 g every 8 hours for a total of 10 days. Children are given 10-15 mg/kg per day, divided into 2 doses, each drip for more than 20 minutes. The course of treatment is 3-7 days.

This product has low toxicity and has almost no toxic reaction when inhaled. The most common adverse reactions after intravenous or oral administration include anemia and fatigue, which disappear after stopping the drug. Less common adverse reactions include fatigue, headache, insomnia, etc., which are more common in those who use large doses, as well as loss of appetite, nausea, etc. Rashes are occasionally seen when inhaled, and medical staff may experience headaches, itchy skin, red skin, and edema around the eyes.

It is contraindicated for those who are allergic to this product or medicines containing this product.

Precautions for children: This experiment has not been conducted and there is no reliable reference. Precautions for pregnancy and lactation: Pregnant women are prohibited from using this product. Precautions for the elderly: This product is not recommended for the elderly.

This product has an antagonistic effect when used together with zidovudine, because this product can inhibit the conversion of zidovudine into active zidovudine phosphate.

Keep tightly closed.

2ml:250mg

36 months

Yichang Humanwell Pharmaceutical Co., Ltd.

• Founded in:

  2001-08-08

• Address:

  No. 19, Dalian Road, Yichang Development Zone, Hubei Province

• Tax NO.:

  91420500730843405M

• Registered Funds:

  293,527,036 yuan

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