Thrombin
Function and Efficacy
It promotes the conversion of fibrinogen into fibrin, which is applied to wounds to cause blood coagulation and stop bleeding.
Ingredients
This product is a sterile lyophilized product of prothrombin extracted from bovine or pig blood and activated to obtain thrombin. The potency of each 1mg should not be less than 10 units. The thrombin content should be more than 80% of the labeled amount.
| Name | Description | Content | CAS NO. | Manufacturer |
|---|---|---|---|---|
| ThrombinIngredients |
It promotes the conversion of fibrinogen into fibrin, which is applied to wounds to coagulate blood and stop bleeding. More |
9002-04-4 | 3 |
Indication
Used for stopping bleeding from small blood vessels that are difficult to ligate during surgery, gastrointestinal bleeding, and bleeding from trauma, etc.
Usage and Dosage
1. For local hemostasis, dissolve sterile sodium chloride injection into a solution of 50-200 units/ml and spray it, or use the dry powder of this product to spray on the wound. 2. For gastrointestinal hemostasis, dissolve it into a solution of 10-100 units/ml with normal saline or warm water (not exceeding 37°C), take it orally or locally by infusion. The concentration and number of times can also be increased or decreased according to the site and degree of bleeding.
Adverse Reactions
1. It may occasionally cause allergic reactions and the drug should be discontinued immediately; 2. There have been reports of low-grade fever reactions when this product was used in surgical hemostasis.
Precautions
Patients with a history of allergy to this product are contraindicated.
Drug Interactions
1. This product will react with acid, alkali and heavy metals and reduce its efficacy; 2. To improve the hemostatic effect of upper gastrointestinal bleeding, it is advisable to take a certain amount of antacid to neutralize gastric acid before taking this product orally, or give acid inhibitors intravenously at the same time; 3. This product can also be dissolved in phosphate buffer (pH 7.6) or cold milk. If a latex solution is prepared with gum arabic, gelatin, fructose gum, honey, etc., the hemostatic effect of thrombin can be improved, and the dosage of this product can be appropriately reduced.
Storage
Seal and store at 4℃～10℃.
Packaging Specification
200 units
Manufacturer
Kunming Baima Pharmaceutical Co., Ltd.
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Founded in:
1995-03-11 -
Address:
No. 998, Kegao Road, High-tech Zone, Kunming City, Yunnan Province -
Tax NO.:
91530100216614669W -
Registered Funds:
10 million yuan -
Website:
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Email: