Sodium Chloride Injection

Sodium chloride is an electrolyte supplement. Sodium and chloride are important electrolytes in the body, mainly present in extracellular fluid, and play a very important role in maintaining normal blood and extracellular fluid volume and osmotic pressure. The normal serum sodium concentration is 135-145mmol/L, accounting for 92% of plasma cations and 90% of total osmotic pressure, so the amount of plasma sodium plays a decisive role in osmotic pressure. The normal serum chloride concentration is 98-106mmol/L. Sodium and chloride ions in the human body are mainly regulated by the hypothalamus, posterior pituitary and kidneys to maintain the stability of body fluid volume and osmotic pressure.

The main component of this product and its chemical name: sodium chloride. Its structural formula is: NaCl Molecular formula: NaCl Molecular weight: 58.44

This product is a colorless, clear liquid with a slightly salty taste.

It is suitable for water loss caused by various reasons, including hypotonic, isotonic and hypertonic water loss; hyperosmotic non-ketotic diabetic coma, the application of isotonic or hypotonic sodium chloride can correct water loss and hyperosmotic state; hypochloremic metabolic alkalosis; external use of normal saline to rinse eyes, wash wounds, etc.; it is also used for obstetric water bag induction of labor.

Hypertonic dehydration During hypertonic dehydration, the osmotic concentration of the patient's brain cells and cerebrospinal fluid increases. If the treatment causes the plasma and extracellular fluid sodium concentration and osmotic concentration to drop too quickly, brain edema may occur. Therefore, it is generally believed that within the first 48 hours of treatment, the plasma sodium concentration should not drop by more than 0.5mmol/L per hour. If the patient is in shock, sodium chloride injection should be given first, and colloid should be supplemented as appropriate. When the shock is corrected, the blood sodium is 155mmol/L, and the plasma osmotic concentration is 350mOsm/L, 0.6% hypotonic sodium chloride injection can be given. When the plasma osmotic concentration is <330mOsm/L, 0.9% sodium chloride injection should be used instead.

1. Excessive and rapid infusion can cause water and sodium retention, resulting in edema, increased blood pressure, increased heart rate, chest tightness, dyspnea, and even acute left heart failure. 2. Excessive and rapid administration of hypotonic sodium chloride can cause hemolysis, cerebral edema, etc.

Contraindicated in pregnancy induced hypertension.

When used as a drug solvent or diluent, attention should be paid to incompatibilities between drugs.

Keep tightly closed.

500ml:4.5g

Shijiazhuang No.4 Pharmaceutical Co., Ltd.

• Founded in:

  1994-06-28

• Address:

  No. 518, Huaian East Road, Shijiazhuang High-tech Industrial Development Zone

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  911301001044060055

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  950 million yuan

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