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Sodium Chloride Injection

Function and Efficacy

Sodium chloride is an electrolyte supplement. Sodium and chloride are important electrolytes in the body. They are mainly present in extracellular fluid and play a very important role in maintaining normal blood and extracellular fluid volume and osmotic pressure. The normal serum sodium concentration is 135-145mmol/L, accounting for 92% of plasma cations and 90% of total osmotic pressure. Therefore, the amount of plasma sodium plays a decisive role in osmotic pressure. The normal serum chloride concentration is 98-106mmol/L. Sodium and chloride ions in the human body are mainly regulated by the posterior lobe of the hypothalamus pituitary gland and the kidneys to maintain the stability of body fluid volume and osmotic pressure.

Ingredients

The main ingredients of this product and its chemical name: Sodium chloride. Its structural formula is: NaCl. Molecular formula: NaCl. Molecular weight: 58.44

Name Description Content CAS NO. Manufacturer
Sodium chlorideIngredients

Sodium chloride is an electrolyte supplement. Sodium and chloride are important electrolytes in the body, mainly present in extracellular fluid, and play a very important role in maintaining normal blood and extracellular fluid volume and osmotic pressure. The normal serum sodium concentration is 135-145mmol/L, accounting for 92% of plasma cations and 90% of total osmotic pressure, so the amount of plasma sodium plays a decisive role in osmotic pressure. The normal serum chloride concentration is 98-106mmol/L. Sodium and chloride ions in the human body are mainly regulated by the posterior lobe of the hypothalamus and pituitary and the kidneys to maintain the stability of body fluid volume and osmotic pressure.

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Appearance

This product is a colorless, clear liquid with a slightly salty taste.

Indication

It is suitable for water loss caused by various reasons, including hypotonic, isotonic and hypertonic water loss; hypertonic non-ketotic diabetic coma can be corrected by using isotonic or hypotonic sodium chloride; hypochloremic metabolic alkalosis; external use of normal saline to wash eyes and wounds, etc.; it is also used for water bag induction in obstetrics

Usage and Dosage

Hypertonic dehydration: During hypertonic dehydration, the osmotic concentration of the patient's brain cells and cerebrospinal fluid increases. If the treatment causes the plasma and extracellular fluid sodium concentration and osmotic concentration to drop too quickly, it may cause cerebral edema. Therefore, it is generally believed that the plasma sodium concentration should not drop by more than 0.5mmol/L per hour within 48 hours after the start of treatment. If the patient is in shock, sodium chloride injection should be given first and colloid should be supplemented as appropriate. When the shock is corrected, the blood sodium is 155mmol/L and the plasma osmotic concentration is 350mOsm/L, 0.6% hypotonic sodium chloride injection can be given. When the plasma osmotic concentration is <330mOsm/L, 0.9% sodium chloride injection can be used instead.

Adverse Reactions

1. Too much and too fast infusion can cause water and sodium retention, resulting in edema, increased blood pressure, increased heart rate, chest tightness, dyspnea, and even acute left heart failure. 2. Too much and too fast administration of hypotonic sodium chloride can cause hemolysis, cerebral edema, etc.

Precautions

Contraindicated in pregnancy induced hypertension

Drug Interactions

When used as a drug solvent or diluent, attention should be paid to the incompatibility between drugs

Storage

Keep tightly closed.

Packaging Specification

100ml:0.9g

Manufacturer

Shandong Kelun Phaemaceutical Co., Ltd.

  • Founded in:

    2004-03-12
  • Address:

    No. 12, Yongzheng Road, Xiaoying Town, Bincheng District, Binzhou City, Shandong Province
  • Tax NO.:

    91371600763665131C
  • Registered Funds:

    100 million yuan
  • Website:

  • Email:

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