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Compound acetylsalicylic acid tablets

Function and Efficacy

It is a compound antipyretic and analgesic drug. Aspirin and phenacetin both have antipyretic and analgesic effects, can inhibit the synthesis and release of prostaglandins in the hypothalamus, restore the normal responsiveness of the receptor neurons in the temperature regulation center, and play an antipyretic and analgesic role; aspirin also has analgesic, anti-inflammatory and anti-rheumatic effects by inhibiting the synthesis of peripheral prostaglandins, etc. Aspirin also has the effect of inhibiting platelet aggregation. Caffeine is a central nervous system stimulant that can excite the cerebral cortex, increase sensitivity to the outside world, and constrict cerebral blood vessels, enhancing the effect of the first two drugs in relieving headaches. Acute toxicity test results: The oral LD50 of rats is 1500mg/kg; the oral LD50 of mice is 1100mg/kg.

Ingredients

Aspirin, phenacetin, caffeine

Name Description Content CAS NO. Manufacturer
Acetylsalicylic acidIngredients

It has antipyretic and analgesic effects, can inhibit the synthesis and release of hypothalamic prostaglandins, restore the normal responsiveness of the receptor neurons in the body temperature regulation center, and thus have antipyretic and analgesic effects; it also has analgesic, anti-inflammatory and anti-rheumatic effects by inhibiting the synthesis of peripheral prostaglandins, and also has the effect of inhibiting platelet aggregation.

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50-78-2 35
PhenacetinIngredients

It has antipyretic and analgesic effects, can inhibit the synthesis and release of prostaglandins in the hypothalamus, restore the normal responsiveness of the receptor neurons in the body temperature regulation center, and thus have an antipyretic and analgesic effect.

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62-44-2 7

Appearance

This product is white tablets.

Indication

Salicylic acid analgesics, anti-inflammatory, antipyretics, anti-rheumatic and platelet inhibition drugs can be used clinically in the following situations. (1) Analgesics and antipyretics: They can relieve mild or moderate pain, such as headaches, toothaches, neuralgia, muscle pain and menstrual pain. They are also used to reduce fever for colds, flu, etc. This product can only relieve symptoms and cannot treat the causes of pain and fever, so other drugs must be used at the same time for causal treatment. (2) Anti-inflammatory and anti-rheumatic: It is the first choice for the treatment of rheumatic fever. After taking the medicine, it can reduce fever, reduce inflammation, improve joint symptoms, and reduce erythrocyte sedimentation rate, but it cannot eliminate the basic pathological changes of rheumatism, nor can it prevent heart damage and other complications. If there is obvious myocarditis, it is generally recommended to use adrenal cortex hormones first, and then add this product after the rheumatic symptoms are controlled and before the hormone is stopped.

Usage and Dosage

Oral: 1-2 tablets each time, 3 times a day, after meals. Children: Antipyretic and analgesic: 10-15 mg per (kg. time), 3-4 times a day.

Adverse Reactions

This product is a compound tablet mainly composed of aspirin and phenacetin. The more common adverse reactions of aspirin include gastrointestinal reactions such as nausea, vomiting, upper abdominal discomfort or pain, which can disappear after stopping the drug; gastrointestinal bleeding or ulcers may occur when used for a long time or in large quantities; reversible tinnitus and hearing loss may occur after taking a certain course of treatment; a few patients may develop allergic reactions such as asthma, urticaria, angioedema or shock, which may cause death in severe cases; excessive doses may cause liver and kidney damage. Phenacetin can cause renal papillary necrosis, interstitial nephritis and acute renal failure, and may even induce renal pelvic cancer and bladder cancer. Phenacetin is also easy to use hemoglobin to form methemoglobin, which reduces the oxygen carrying capacity of the blood and causes cyanotic reactions. In addition, phenacetin can also cause hemolysis and hemolytic anemia, and has certain toxicity to the retina. Long-term use of phenacetin can also cause dependence on the drug. Phenacetin can also cause liver damage.

Precautions

It is contraindicated for patients who are allergic to aspirin or other nonsteroidal anti-inflammatory drugs and caffeine, hemophilia, active peptic ulcer and other gastrointestinal bleeding. It is contraindicated for infants under 3 months old.

Drug Interactions

Not yet clear

Storage

Keep away from light and store in a sealed container.

Packaging Specification

Aspirin 0.22g, Phenacetin 0.15g, Caffeine 35mg

Manufacturer

Jilin Aodong Yanbian Pharmaceutical Co., Ltd.

  • Founded in:

    2001-12-27
  • Address:

    No. 2158, Aodong Street, Dunhua City, Jilin Province
  • Tax NO.:

    91222403732565090W
  • Registered Funds:

    824.904665 million yuan
  • Website:

  • Email:

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