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Dimenhydrinate Tablets

Function and Efficacy

According to the data, after a healthy person takes 40 mg of this product, it is mainly absorbed through the digestive tract and partially absorbed from the oral mucosa. The blood concentration reaches the peak value in about 2 hours, and the peak concentration (Cmax) is about 111.36 ng/ml, and the elimination half-life is 11.47 hours. This product is metabolized in the liver and excreted from the urine in the form of metabolites.

Ingredients

The main ingredients of this product are dimenhydrinate, and its chemical name is: 1,3-dimethyl-8-chloro-1H-2,6-dione and N,N-dimethyl-2-(diphenylmethoxy)ethylamine.

Name Description Content CAS NO. Manufacturer
DimenhydrinateIngredients

After a healthy person takes 40 mg of this product, it is mainly absorbed through the digestive tract and partially absorbed from the oral mucosa. The blood concentration reaches the peak value in about 2 hours, the peak concentration (Cmax) is about 111.36 ng/ml, and the elimination half-life is about 11.47 hours. This product is metabolized in the liver and excreted from the urine in the form of metabolites.

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523-87-5 10

Appearance

This product is green and white oval tablets.

Indication

It is suitable for the prevention and treatment of motion sickness, nausea and vomiting caused by motion sickness, radiation sickness, postoperative vomiting, drug-induced nausea and vomiting, and symptomatic treatment of nausea and vertigo caused by Meniere's disease and other labyrinthine and inner ear vertigo diseases.

Usage and Dosage

When nausea, vomiting, dizziness and other symptoms begin to appear, take it sublingually. 3 to 6 times a day. Adults take 1 to 2 tablets each time, not more than 12 tablets a day. Children aged 7 to 12 years old take half a tablet each time, not more than 6 tablets a day.

Adverse Reactions

1 Common symptoms include: sluggishness, sleepiness, lack of concentration, fatigue, dizziness, and nausea, vomiting, and loss of appetite. 2 Rare symptoms include: hallucinations, illusions, decreased night vision, decreased solid vision, extrapyramidal symptoms or rashes. 3 Overdose symptoms include vomiting, dizziness, convulsions, cyanosis, coma, and even respiratory failure. In toxic doses, severe delirium similar to atropine poisoning may occur, accompanied by extrapyramidal symptoms, and chlordiazepoxide (chlordiazepoxide) and infusion can be used for symptomatic treatment.

Precautions

It is contraindicated for patients who are allergic to the ingredients of this product or other ethanolamine drugs.

Special Population Medication

Precautions for children: Not suitable for newborns and premature infants. Precautions for pregnancy and lactation: Not suitable for pregnant women. Precautions for the elderly: Not clear yet.

Drug Interactions

1. This product has a synergistic effect when used with ethanol or other sedatives and hypnotic drugs, so it should be avoided to take them at the same time. 2. This product can temporarily affect the absorption of barbiturates, etc. 3. When this product is used with sodium para-aminosalicylate, the latter's blood concentration is reduced. 4. If used with other drugs at the same time, drug interactions may occur. Please consult a doctor or pharmacist for details.

Storage

Seal and store in a dry place. Validity period: tentatively two years.

Packaging Specification

50mg

Validity Period

36 months.

Manufacturer

Shanghai Sine Pharmaceutical Laboratories Co., Ltd.

  • Founded in:

    1993-10-23
  • Address:

    No. 905, Xinjinqiao Road, China (Shanghai) Pilot Free Trade Zone
  • Tax NO.:

    91310000133742534B
  • Registered Funds:

    1,191,611,312 yuan
  • Website:

  • Email:

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