Diphenhydramine Hydrochloride Injection
Function and Efficacy
It is a derivative of ethanolamine. Its antihistamine effect is not as good as promethazine, and its duration of action is also shorter. The sedative effect of the two drugs is the same, with local anesthesia, antiemetic and anti-M cholinergic effects. 1. Antihistamine effect, which can compete with histamine released from tissues for H1 receptors on effector cells, thereby stopping allergic reactions; 2. Inhibition of central nervous system activity causes sedative and hypnotic effects; 3. Strengthens the effect of antitussive drugs. 4. It also has anti-vertigo and anti-tremor paralysis effects
Ingredients
Diphenhydramine. Chemical name: N, N-dimethyl-2-(diphenylmethoxy)ethylamine hydrochloride. Its structural formula is: C17H21NOHCl291.82
| Name | Description | Content | CAS NO. | Manufacturer |
|---|---|---|---|---|
| DiphenhydramineIngredients |
It is a derivative of ethanolamine. Its antihistamine effect is not as good as promethazine, and its duration of action is also shorter. The sedative effect of the two drugs is the same, with local anesthesia, antiemetic and anti-M cholinergic effects. 1. Antihistamine effect, which can compete with histamine released from tissues for H1 receptors on effector cells, thereby stopping allergic reactions; 2. Inhibition of central nervous system activity causes sedative and hypnotic effects; 3. Strengthens the effect of antitussive drugs. 4. It also has anti-vertigo and anti-tremor paralysis effects More |
58-73-1 | 3 |
Appearance
This product is a colorless clear liquid.
Indication
It is mainly used for: acute severe allergic reactions, to reduce allergic reactions caused by blood transfusion or plasma; nausea and vomiting caused by drugs after surgery; Parkinson's disease and extrapyramidal symptoms; dental local anesthesia, when the patient is highly allergic to commonly used local anesthetics, 1% diphenhydramine solution can be used as a dental local anesthetic; other allergic reactions, those who are not suitable for oral medication.
Usage and Dosage
Deep intramuscular injection, 20 mg at a time, 1 to 2 times a day.
Adverse Reactions
1 Common symptoms include: central nervous system depression, ataxia, nausea, vomiting, loss of appetite, etc. 2 Rare symptoms include: shortness of breath, chest tightness, cough, dystonia, etc. There are reports that trismus and laryngeal spasm may occur after administration. 3 Occasionally, it may cause rash, neutropenia, anemia and heart rate disorders.
Precautions
It is contraindicated for patients with myasthenia gravis, angle-closure glaucoma, prostatic hypertrophy, those who are allergic to this product and excipients, newborns, and premature infants.
Special Population Medication
Precautions for children: Not clear yet. Precautions for pregnancy and lactation: 1. The use of this product during pregnancy may increase the incidence of cleft palate, inguinal hernia and urogenital malformations in infants, so pregnant women should use it with caution; 2. A small amount of this product can be excreted from breast milk, so it is not suitable for lactating women. Precautions for the elderly: Slow reaction, dizziness, etc. may occur.
Drug Interactions
This product can temporarily affect the absorption of barbiturates and sodium sulfacetamide. When used together with sodium para-aminosalicylate, it can reduce the latter's blood concentration. It can enhance the effect of central nervous system depressants.
Storage
Keep away from light and store in a sealed container.
Packaging Specification
1 ml: 20 mg
Validity Period
36 months
Manufacturer
Guangzhou Baiyunshan Mingxing Pharmaceutical Co., Ltd.
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Founded in:
1962-12-27 -
Address:
No. 48, North Industrial Avenue, Haizhu District, Guangzhou -
Tax NO.:
9144010119046020XE -
Registered Funds:
46.091897 yuan -
Website:
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Email: