Lycorinehydrochloride
2188-68-3
Pharmaceutical Grade
SHANGHAI
25kg/0.12kg Bag
2017-01-19
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Product Description
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Seller Information
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DescriptionECHEMI Editorial ReferenceLycorine (hydrochloride) is VE-cadherin inhibitor,and has IC50 of 1.2μM in Hey1B cell.IC50: 1.2μM (Hey1B cell)[2]In vitro:Lycorine (hydrochloride) executed an anti-melanoma vasculogenic effect by inhibiting VE-cadherin gene expression in C8161 cells and caused a decrease in cell surface exposure of VE-cadherin protein. Consistently, LH significantly suppressed VE-cadherin gene promoter activity. [1]Lycorine (hydrochloride) effectively inhibited mitotic proliferation of Hey1B cells (halfBasic Info
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Product Name:
1H-[1,3]Dioxolo[4,5-j]pyrrolo[3,2,1-de]phenanthridine-1,2-diol, 2,4,5,7,12b,12c-hexahydro-, hydrochloride (1:1), (1S,2S,12bS,12cS)-
Other Name:1H-[1,3]Dioxolo[4,5-j]pyrrolo[3,2,1-de]phenanthridine-1,2-diol,2,4,5,7,12b,12c-hexahydro-,hydrochloride (1:1),(1S,2S,12bS,12cS)-;Lycoran-1α,2β-diol,3,3a-didehydro-,hydrochloride;1H-[1,3]Dioxolo[4,5-j]pyrrolo[3,2,1-de]phenanthridine-1,2-diol,2,4,5,7,12b,12c-hexahydro-,hydrochloride,(1S,2S,12bS,12cS)-;Galanthan-1,2-diol,3,12-didehydro-9,10-[methylenebis(oxy)]-,hydrochloride,(1α,2β)-;Lycorine hydrochloride;Licorin hydrochloride
CAS No.:2188-68-3
Molecular Formula:C16H17NO4.ClH
InChIKeys:InChIKey=VUVNTYCHKZBOMV-NVJKKXITSA-N
Molecular Weight:287.31
Exact Mass:323.092
EC Number:207-503-6
UNII:58F70VH0HS
Categories:
Characteristics-
PSA:
62.2
XLogP3:0.68650
Appearance:fine crystal powder.
Melting Point:206 °C
Boiling Point:477.4°C at 760 mmHg
Flash Point:242.5ºC
Storage Conditions:2-8°C
Vapor Pressure:6.37E-10mmHg at 25°C
Hazard IdentificationClassification of the substance or mixture
Acute toxicity - Category 3, Oral
GHS label elements, including precautionary statements
Pictogram(s) 
Signal word Danger
Hazard statement(s) H301 Toxic if swallowed
Precautionary statement(s) Prevention P264 Wash ... thoroughly after handling.
P270 Do not eat, drink or smoke when using this product.
Response P301+P316 IF SWALLOWED: Get emergency medical help immediately.
P321 Specific treatment (see ... on this label).
P330 Rinse mouth.
Storage P405 Store locked up.
Disposal P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
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Seller Information
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Business Type:
Manufactory
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Location:
City mansion, the 4rd road of High-tech zone,Baoji City, Shaan'xi province, China.
Baoji Guokang Bio-Technology Co.,Ltd as a leading manufacture of herbal extracts in China. With over 10 years of combined experience in the industry, By using natural plants as raw material, adopting modern high technology combined with traditional Chinese Health theory, GuoKang provides superior natural organic products and one-stop technical services for industries involved in natural medicine, functional food, food additives, natural cosmetics, essence and flavors. GuoKang has a strong R&D team and cooperates closely with a number of research institutes and universities. All these can ensure GuoKang's plant extract products to met--and even exceeded—the world highest industry standards for quality and purity. “High Quality and Honest” are our root . Guokang's products has already exported to many countries and gain the most favorable reputation from USA, Europe, Japan, Korea, South East Asia etc.
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