Sulfobutyl ether-beta-cyclodextrin sodium salt
1 Inquiries
182410-00-0
Injection Grade
100%
QINGDAO
25kg/0.5kg White Plastic Bottle (Sample Bottle)
2017-10-24
hydroxypropyl-beta-cyclodextrin,Sulfobutyl ether-beta-cyclodextrin sodium salt
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Product Description
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Seller Information
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Inquiry History
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Description
DMF No.: 030167
Name: sulfobutyl ether-beta-cyclodextrin sodium salt
Other name : betadex sulfobutyl ether sodium ; sulfobutyl ether-β-cyclodextrin sodium salt
CAS: 182410-00-0
Abbreviation: SBEBCD
Molecular formula : C42H70-nO35 (C4H8O3S Na)n
Molecular weight: 1135+158n
Qaulity ： injection grade / oral grade
Standard : USP39 / EP9.0
Package: 500g/bag , 1kg/bag , 2kg/bag, 10kg/drum , 20kg/drum or customized
Use : medical
Specification : USP39
ITEMS
SPECIFICATION
RESULTS
Appearance
White to off-white solid, free from foreign matter
Qualify
Solution Clarity
A 30%w/v solution in water is clear and essentially free from particles of foreign matter
Qualify
Identification (IR)
Consistent with SBECD standard
Qualify
Sodium Identification
Identify test are positive for Sodium
+
Average Degree of Substitution
6.2-6.9
6.7
SBE 1 Content
≤0.2%
0.05%
SBE 2 Content
≤0.8%
0.15%
Water solution pH
pH of 30%w/v solution in water is 4.0-6.8
5.4
Heavy Metals
≤5ppm
<5ppm
Water
≤10%
4.0%
β-Cyclodextrin Content
≤0.1%
Absence
Sodium Chloride
≤0.2%
0.01%
1,4-butane sultone
≤0.5ppm
0.3ppm
4-Hydroxybutane-1-Sulfonic Acid
≤0.09%
0.01%
Disodium bis-(4-sulfobtyl) ether
≤0.05%
0.05%
Assay
95%-105%
99.5%
Bacterial endotoxins
≤25EU/g
≤20EU/g
Microbiology
Total viable aerobic count (mould plus yeast)
≤100CFU/g
20CFU/g
Escherichia Coli
Absence
Absence
Salmonella species
Absence
Absence
mould plus yeast
≤50CFU/g
Absence
Features and applications:
sulfobutyl ether-beta-cyclodextrin sodium salt is a high water-soluble anionic cyclodextrin derivative. It can easily form non-covalent inclusion complexes with drug molecules, thus it has the good performances in enhancing drug stability, solubility and safety, reducing drug toxicity and hemolysis, covering up bad smell, and controlling drug release rate.
sulfobutyl ether-beta-cyclodextrin sodium salt has been used in injection, oral, nasal and eye medication. Modification by charged functional units can improve the binding affinity of cyclodextrins for oppositely charged guests, so it has a special affinity for drugs with nitrogen elements.
Basic Info-
Product Name:
β-Cyclodextrin, sulfobutyl ethers, sodium salts
Other Name:β-Cyclodextrin,sulfobutyl ethers,sodium salts
CAS No.:182410-00-0
Molecular Weight:1134.9842
EC Number:1308068-626-2
Categories:
CharacteristicsHazard IdentificationClassification of the substance or mixture
Not classified.
GHS label elements, including precautionary statements
Pictogram(s) No symbol. Signal word No signal word
Hazard statement(s) none
Precautionary statement(s) Prevention none
Response none
Storage none
Disposal none
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
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Seller Information
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Business Type:
Manufactory
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Main Products:
hydroxypropyl-beta-cyclodextrin,Sulfobutyl ether-beta-cyclodextrin sodium salt
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Location:
Binzhou city, binzhou city, shandong province
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Payment Terms:
D/P
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Total Annual Revenue:
$50 million-$100 million
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Total Employees:
51-100
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Certifications:
ISO,DMF
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Inquiry History1 Inquiries
Country Product Purchase Quantity Date Posted 
Cyprus
Betadex Sulfobutyl Ether Sodium(SBE-β-CD) Injection grade EP/USP
1 KG Oct 15, 2024 Post an enquiry for this product