Dacomitinib 99%
1110813-31-4
Pharmaceutical Grade
99%
QINGDAO
10kg/0.12kg Bag
2018-11-30
Dacomitinib
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Product Description
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Seller Information
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DescriptionDacomitinib (PF299804) is a potent, irreversible pan-ErbB inhibitor with the most effective effect on EGFR, IC50 is 6 nM, highly effective on carrying EGFR or ERBB2 mutants (anti-Gefitinib) and carrying EGFR T790M mutant NSCLCs. Phase 2.Boiling point: 665.7±55.0 °C(Predicted)
Density: 1.344
Form: White solid.
Acidity coefficient (pKa): 12.05±0.43 (Predicted)
CAS database: 1110813-31-4Basic Info-
Product Name:
Dacomitinib
Other Name:2-Butenamide,N-[4-[(3-chloro-4-fluorophenyl)amino]-7-methoxy-6-quinazolinyl]-4-(1-piperidinyl)-,(2E)-;(2E)-N-[4-[(3-Chloro-4-fluorophenyl)amino]-7-methoxy-6-quinazolinyl]-4-(1-piperidinyl)-2-butenamide;Dacomitinib;PF 00299804;PF 299804;PF 299;1006885-28-4
CAS No.:1110813-31-4
Molecular Formula:C24H25ClFN5O2
InChIKeys:InChIKey=LVXJQMNHJWSHET-AATRIKPKSA-N
Molecular Weight:469.9390032
Exact Mass:469.94
EC Number:-0
UNII:2XJX250C20
DSSTox ID:DTXSID50149493
ATC Code:L01EB07|L - Antineoplastic and immunomodulating agents
HScode:29335990
Categories:
Characteristics-
PSA:
79.4
XLogP3:4.4
Density:1.3±0.1 g/cm3
Melting Point:184-187 ºC
Boiling Point:665.7±55.0°C at 760 mmHg
Flash Point:356.4±31.5 °C
Refractive Index:1.663
Water Solubility:<1 mg/mL
Hazard IdentificationClassification of the substance or mixture
no data available
GHS label elements, including precautionary statements
Pictogram(s) no data available Signal word no data available
Hazard statement(s) no data available
Precautionary statement(s) Prevention no data available
Response no data available
Storage no data available
Disposal no data available
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
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Seller Information
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Business Type:
Manufactory
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Main Products:
Dacomitinib
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Payment Terms:
D/P,L/C
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Average lead Time:
60
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Total Annual Revenue:
Less than $1 million
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Year of Establishment:
2015
Beilang Biology and many well-known universities and scientific research institutions such as Wuhan University, Shanghai University, China Medical University, China Pharmaceutical University, Shenyang Pharmaceutical University, Shanghai Life Science Research Institute, China Institute of Biotechnology, etc. in the research and development of new drugs Cooperation. At the same time, it has extensive cooperation with major pharmaceutical companies such as CSPC, Huayao Group, Lambeau Pharmaceutical, etc. to jointly develop export business. For a long time, colleagues regard Beilang as a long-term reliable partner. We also hope to cooperate more with colleagues in the industry, and move towards a better tomorrow together with the aim of "mutual benefit and mutual growth".
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