erlotinib hydrochloride
2 Inquiries
183319-69-9
Industrial Grade
99%
SHANGHAI
25kg/Cardboard Drum
2020-08-19
Anti-tumor categories,Cardiovascular,Anti-Diabetes Class,4-(4-bromo-2-fluoroanilino)-6-methoxy-1H-quinazolin-7-one,4-Amino-3-chlorophenol hydrochloride,4-Amino-3-chlorophenol
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Product Description
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Seller Information
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Inquiry History
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DescriptionECHEMI Editorial ReferenceErlotinib hydrochloride inhibits purified EGFR kinase with an IC50 of 2 nM.
Erlotinib Hydrochloride is the hydrochloride salt of a quinazoline derivative with antineoplastic properties. Competing with adenosine triphosphate, erlotinib reversibly binds to the intracellular catalytic domain of epidermal growth factor receptor (EGFR) tyrosine kinase, thereby reversibly inhibiting EGFR phosphorylation and blocking the signal transduction events and tumorigenic effects associated with EGFR activation.|A quinazoline derivative and ANTINEOPLASTIC AGENT that functions as a PROTEIN KINASE INHIBITOR for EGFR associated tyrosine kinase. It is used in the treatment of NON-SMALL CELL LUNG CANCER.Basic Info-
Product Name:
Erlotinib hydrochloride
Other Name:4-Quinazolinamine,N-(3-ethynylphenyl)-6,7-bis(2-methoxyethoxy)-,hydrochloride (1:1);4-Quinazolinamine,N-(3-ethynylphenyl)-6,7-bis(2-methoxyethoxy)-,monohydrochloride;CP 358774;OSI 774;Tarceva;6,7-Bis(2-methoxyethoxy)-4-(3-ethynylanilino)quinazoline hydrochloride;[6,7-Bis(2-methoxyethoxy)quinazolin-4-yl]-(3-ethynylphenyl)amine hydrochloride;Erlotinib hydrochloride
CAS No.:183319-69-9
Molecular Formula:C22H23N3O4.ClH
InChIKeys:InChIKey=GTTBEUCJPZQMDZ-UHFFFAOYSA-N
Molecular Weight:429.89700
Exact Mass:429.14600
UNII:DA87705X9K
NSC Number:718781
DSSTox ID:DTXSID10171412
NCI Thesaurus Code:C2693
ATC Code:L01EB02
HScode:2933990090
Categories:
Characteristics-
PSA:
74.73000
XLogP3:4.28010
Appearance:White or off-white powder
Melting Point:219-221 °C @ Solvent: Methanol
Boiling Point:553.6ºC at 760 mmHg
Flash Point:288.6ºC
Vapor Pressure:4.52E-12mmHg at 25°C
Hazard IdentificationClassification of the substance or mixture
Acute toxicity - Category 4, Oral
Carcinogenicity, Category 2
Reproductive toxicity, Category 2
Hazardous to the aquatic environment, long-term (Chronic) - Category Chronic 2
GHS label elements, including precautionary statements
Pictogram(s)
Signal word Warning
Hazard statement(s) H302 Harmful if swallowed
H351 Suspected of causing cancer
H361 Suspected of damaging fertility or the unborn child
H411 Toxic to aquatic life with long lasting effects
Precautionary statement(s) Prevention P264 Wash ... thoroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P203 Obtain, read and follow all safety instructions before use.
P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...
P273 Avoid release to the environment.
Response P301+P317 IF SWALLOWED: Get medical help.
P330 Rinse mouth.
P318 IF exposed or concerned, get medical advice.
P391 Collect spillage.
Storage P405 Store locked up.
Disposal P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
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Seller Information
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Business Type:
Manufactory
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Main Products:
Anti-tumor categories,Cardiovascular,Anti-Diabetes Class,4-(4-bromo-2-fluoroanilino)-6-methoxy-1H-quinazolin-7-one,4-Amino-3-chlorophenol hydrochloride,4-Amino-3-chlorophenol
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Location:
No.9 Weidi Road-Jiangsu Life Science and Technology Innovation Park, Nanjing, P.R.C
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Payment Terms:
TT against copy of documents
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Average lead Time:
7 days
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Total Annual Revenue:
$2.5 million-$5 million
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Total Employees:
11-50
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Year of Establishment:
2008
Company Certificates-
business license
Nanjing CHICO Pharmaceutical Co., Ltd is a high-tech enterprise specializing in R&D, production and sales of APIs and pharmaceutical intermediates. We are recognized as National High-Tech Enterprises by Science and Technology Department of Jiangsu Province in 2014.Adhering to the "Consummate service Convincing honor" business strategy, CHICO will provide you the qualified products and first-class service which are based on our strong technical accumulation and outstanding professionalism.
CHICO was established in July 2008, our sales office and R&D center is located in No.9 Weidi Road -Jiangsu life science and Technology Innovation Park, covering an area of about 1800 square meters. Our GMP factory is located in AnQing--- AnQing CHICO pharmaceutical Co., LTD, with a total area of 20000 square meters. Meanwhile, we also have set our cooperative production base in Huai’an. Now we have a complete ,stable production chain of gram-kilogram-ton so that we can achieve rapid response in the whole R&D-scale up- producing process for new products at the first time.
We always regard the quality as life, thus we have established our quality department which is directly controlled by GM. Also we have set a perfect quality assurance system and strict quality control standards according to the GMP requirements' and we have already passed the ISO 9001 quality system certification.
We warmly thank the new and old customers that support and cooperate with us. We sincerely look forward to using "integrity, quality, efficient, professional" service to enhance mutual friendship and create brilliance hand in hand with you!
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Inquiry History2 Inquiries
Country Product Purchase Quantity Date Posted
Pakistan
Erlotinib Hydrochloride
1 KG Jun 23, 2025
Pakistan
ERLOTINIB HCL
3.00 KG Dec 31, 2024 Post an enquiry for this product
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