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Edoxaban(Cas No.:480449-70-5) 99% white power Edoxaban(Cas No.:480449-70-5) HRD

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CAS No.:

480449-70-5

Grade:

Pharmaceutical Grade

Content:

99%

Port:

Guangzhou

Brand:

HRD

Packaging:

25kg/drum

Price valid (until):

2021-10-27

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Zhuhai Hairuide Bioscience and Technology Co., Ltd

Company Type:

Manufactory

Location:

China

Qualification:

Main Products:

Fimasartan and intermediates,Ticagrelor and intermediates,Oseltamivir Phosphate and intermediates,Edoxaban (tosylate),Fluvoxamine maleate and intermediates,Orlistat and Intermediates

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Product Description
Seller Information
Inquiry History

Description

Specification: 25kg/barrel

Level: Medical Grade Model:

Edoxaban Item Number: 480449-70-5

Appearance: White Powder

Product Name: Edoxaban

CAS Number: 480449-70-5

EINECS Number: 1592732-453-0

Purity of Duxaban: 99

Uses: Pharmaceutical raw materials

Molecular formula: C24H30ClN7O4S

Basic Info

Product Name:

Edoxaban

Other Name:

Ethanediamide,N1-(5-chloro-2-pyridinyl)-N2-[(1S,2R,4S)-4-[(dimethylamino)carbonyl]-2-[[(4,5,6,7-tetrahydro-5-methylthiazolo[5,4-c]pyridin-2-yl)carbonyl]amino]cyclohexyl]-;Ethanediamide,N-(5-chloro-2-pyridinyl)-N′-[(1S,2R,4S)-4-[(dimethylamino)carbonyl]-2-[[(4,5,6,7-tetrahydro-5-methylthiazolo[5,4-c]pyridin-2-yl)carbonyl]amino]cyclohexyl]-;N1-(5-Chloro-2-pyridinyl)-N2-[(1S,2R,4S)-4-[(dimethylamino)carbonyl]-2-[[(4,5,6,7-tetrahydro-5-methylthiazolo[5,4-c]pyridin-2-yl)carbonyl]amino]cyclohexyl]ethanediamide;Edoxaban;DU 176;N-(5-Chloropyridin-2-yl)-N′-[(1S,2R,4S)-4-[(dimethylamino)carbonyl]-2-[[(5-methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridin-2-yl)carbonyl]amino]cyclohexyl]ethanediamide;876652-15-2

CAS No.:

480449-70-5

Molecular Formula:

C24H30ClN7O4S

InChIKeys:

InChIKey=HGVDHZBSSITLCT-JLJPHGGASA-N

Molecular Weight:

548.065

Exact Mass:

548.06

EC Number:

1592732-453-0

UNII:

NDU3J18APO

DSSTox ID:

DTXSID50197398

NCI Thesaurus Code:

C96539

Color/Form:

White to pale yellowish-white crystalline powder

ATC Code:

B01|B01AF03|B - Blood and blood forming organs

HScode:

2934999090

Categories:

Other Chemical Drugs

Characteristics

PSA:

165

XLogP3:

1.4

Density:

1.4±0.1 g/cm3

Melting Point:

Crystals as monohydrate from ethanol + water. MP: 245-48 (decomposes) /Edoxaban tosylate/

Refractive Index:

1.646

Water Solubility:

In water, 93.29 mg/L at 25 °C (est)

Storage Conditions:

Keep container tightly closed in a dry and well-ventilated place. Recommended storage temperature: -20 °C. /Edoxaban tosylate/|Store at 20-25 °C (68-77 °F); excursions permitted to 15 deg - 30 °C (59 deg - 86 °F). /Edoxaban tosylate/

Vapor Pressure:

2.03X10-21 mm Hg at 25 °C (est)

PKA:

6.7None

Henrys Law Constant:

Henry's Law constant = 3.11X10-34 atm-cu m/mol at 25 °C (est)

Dissociation Constants:

pKa 6.7 /Edoxaban tosylate/

Experimental Properties:

The solublilty decreases with increasing pH. It is slightly soluble in water, pH 3 to 5 buffer, very slightly soluble at pH 6 to 7; practically insoluble at pH 8 to 9 /Edoxaban tosylate/|Hydroxyl radical reaction rate constant = 1.55X10-12 cu cm/molec-sec at 25 °C (est)

See More Edoxaban Properties 

Hazard Identification

Classification of the substance or mixture

no data available

GHS label elements, including precautionary statements

Precautionary statement(s)
Pictogram(s)	no data available
Signal word	no data available
Hazard statement(s)	no data available
Prevention	no data available
Response	no data available
Storage	no data available
Disposal	no data available

Other hazards which do not result in classification

no data available

Handling and Storage

Precautions for safe handling

Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Conditions for safe storage, including any incompatibilities

Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

See More Edoxaban Safety Data Sheet 

Seller Information

Business Type:
Manufactory

Main Products:
Fimasartan and intermediates,Ticagrelor and intermediates,Oseltamivir Phosphate and intermediates,Edoxaban (tosylate),Fluvoxamine maleate and intermediates,Orlistat and Intermediates

Location:
No.2 Workshop, NO.10 Yonghui Road, Sanzao Town, Jinwan District, Zhuhai City, Guangdong Province, China

Payment Terms:
TT against copy of documents,D/P,L/C,D/A

Average lead Time:
7

Total Annual Revenue:
$10 million-$25 million

Total Employees:
51-100

Year of Establishment:
2009

Certifications:
Business Lincense,High-tech Enterprise,IP,ISO

Zhuhai Hairuide Bioscience and Technology Co., Ltd., is one of the GMP factory located in Pharmaceutical Industry zone of Zhuhai City, covering an area around 6000 square meters.HRD is a vertically integrated company for R&D, production and sale pharmaceutical industry.Our hit products include Oseltamivir Phosphate, Fimasartan,Tenofovir disoproxil, zonisamide, Ilaprazole, Fluvoxamine maleate,tripleidine hydrochloride,Ticagrelor, Tenofovir,Tavaborole with its intermediates and so on.
Our new plant started its construction in 2019, which will has six production workshop to be finished at the beginning of 2022. The new site design is following the guideline of GMP,EDQM and USFDA. We have the technical of Grignard reaction, ultra-low temperature anhydrous and oxygen-free reaction technology development, process optimization, pilot scale-up and large-scale production business, so you are most welcome to discussion for the CMO,CDMO cooperation.

Inquiry History

1 Inquiries

Country	Product	Purchase Quantity	Date Posted
China	Edoxaban TBSYLATE MONOHYDRATE 99% white powder	1 MT	Jul 4, 2023

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