99% Pharmaceutical Raw Materials CAS 3778-73-2 Ifosfamide
3778-73-2
Shanghai, China
25kg/Drum
2022-12-31
Dichloromethane,Linocaine hydrochloride
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Product Description
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Seller Information
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Description
Ifosfamide Chemical Properties Melting point 48°C Boiling point 336.1±52.0 °C(Predicted) density 1.33±0.1 g/cm3(Predicted) storage temp. 2-8°C pka 1.44±0.20(Predicted) form neat CAS DataBase Reference 3778-73-2(CAS DataBase Reference) IARC 3 (Vol. 26, Sup 7) 1987 EPA Substance Registry System Isophosphamide (3778-73-2) 
ECHEMI Editorial ReferenceIfosfamide is an alkylating chemotherapeutic agent with activity against a wide range of tumors.
Solid
Ifosfamide is the simplest member of the class of ifosfamides that is 1,3,2-oxazaphosphinan-2-amine 2-oxide substituted by 2-chloroethyl groups on both the nitrogen atoms respectively. It is a nitrogen mustard alkylating agent used in the treatment of advanced breast cancer. It has a role as an antineoplastic agent, an immunosuppressive agent, an alkylating agent, an environmental contaminant and a xenobiotic.|Ifosfamide is a chemotherapeutic agent chemically related to the nitrogen mustards and a synthetic analog of cyclophosphamide. It is active as an alkylating agent and an immunosuppressive agent.|Ifosfamide is a parenterally administered alkylating agent similar to cyclophosphamide that is used in the treatment of several forms of cancer including lymphomas, sarcoma and advanced forms of solid organ cancer such as breast, testicular, ovarian, gastric and lung cancer. Ifosfamide therapy is associated with minor transient serum enzyme elevations and has been linked to cases of acute liver injury, including acute cholestatic hepatitis and veno-occlusive disease.|Positional isomer of CYCLOPHOSPHAMIDE which is active as an alkylating agent and an immunosuppressive agent.Basic Info-
Product Name:
Ifosfamide
Other Name:2H-1,3,2-Oxazaphosphorin-2-amine,N,3-bis(2-chloroethyl)tetrahydro-,2-oxide;2H-1,3,2-Oxazaphosphorine,3-(2-chloroethyl)-2-[(2-chloroethyl)amino]tetrahydro-,2-oxide;A 4942;3-(2-Chloroethyl)-2-(2-chloroethylamino)tetrahydro-2H-1,3,2-oxaazaphosphorin 2-oxide;Ifosfamide;3-(2-Chloroethyl)-2-(2-chloroethylamino)tetrahydro-2H-1,3,2-oxazaphosphorine 2-oxide;Asta Z 4942;Isoendoxan;Isophosphamide;NSC 109724;Ifosfamid;Iphosphamide;3-(2-Chloroethyl)-2-(2-chloroethylamino)tetrahydro-2H-1,3,2-oxazaphosphorin 2-oxide;Holoxan 1000;Isofosfamide;Z 4942;Ifomide;Ifosphamide;Mitoxana;Holoxan;(±)-Ifosfamide;Cyfos;Naxamide;Ifex;MJF 9325;Ifosfomide;(2-Chloro-ethyl)-[3-(2-chloro-ethyl)-2-oxo-2λ*5*-[1,3,2]oxazaphosphinan-2-yl]-amine;36341-88-5;84711-20-6
CAS No.:3778-73-2
Molecular Formula:C7H15Cl2N2O2P
InChIKeys:InChIKey=HOMGKSMUEGBAAB-UHFFFAOYSA-N
Molecular Weight:261.09
Exact Mass:261.09
EC Number:223-237-3
NSC Number:759154|109724
DSSTox ID:DTXSID7020760
Color/Form:Crystals from anhyd ether|White crystalline powder
ATC Code:L01AA06|L - Antineoplastic and immunomodulating agents
HScode:2934999090
Categories:
Characteristics-
PSA:
41.6
XLogP3:0.9
Appearance:Solid
Density:1.3±0.1 g/cm3
Melting Point:39-41 °C
Boiling Point:336.1°C at 760 mmHg
Flash Point:157.1±30.7 °C
Refractive Index:1.506
Water Solubility:1.50e+01 g/L
Storage Conditions:2-8°C
Toxicity:LD50 in rats (mg/kg): 160 i.p. (Arnold, 1973); also reported as 150 i.p. (Brock)
Collision Cross Section:147 Ų [M+H]+ [CCS Type: TW, Method: calibrated with polyalanine and drug standards]
Hazard IdentificationClassification of the substance or mixture
Acute toxicity - Category 3, Oral
Eye irritation, Category 2
GHS label elements, including precautionary statements
Pictogram(s) 
Signal word Warning
Hazard statement(s) H301 Toxic if swallowed
H319 Causes serious eye irritation
Precautionary statement(s) Prevention P264 Wash ... thoroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...
Response P301+P316 IF SWALLOWED: Get emergency medical help immediately.
P321 Specific treatment (see ... on this label).
P330 Rinse mouth.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
Storage P405 Store locked up.
Disposal P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Intact vials of ifosfamide should be stored at room temp. Ifosfamide may liquefy at temperatures above 35 deg C.
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Seller Information
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Business Type:
Manufactory
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Main Products:
Dichloromethane,Linocaine hydrochloride
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Location:
BUILDING 1,HISENSE INTELLIGENCE VALLEY,NO.2116,OF PHOEIX ROAD, HIGH-TECH ZONE ,JINAN CITY ,SHANDONG PROVINCE,CHINA
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Payment Terms:
D/P,L/C,D/A
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Average lead Time:
15
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Total Annual Revenue:
$10 million-$25 million
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Total Employees:
11-50
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Year of Establishment:
2016
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Country Product Purchase Quantity Date Posted Post an enquiry for this product