CAS 58-32-2 Dipyridamole with Best Price
58-32-2
Shanghai, China
Zhishang Chem
100g; 1kg; 25g
2022-12-31
Dichloromethane,Linocaine hydrochloride
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Product Description
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Seller Information
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Description

Melting point 165-166 °C(lit.) Boiling point 593.96°C (rough estimate) density 1.2046 (rough estimate) refractive index 1.6910 (estimate) storage temp. −20°C solubility DMSO: soluble form powder pka pKa 6.4 (Uncertain) color yellow Water Solubility Soluble in chloroform, methanol, dilute acids, ethanol. Slightly soluble in water. 


Packing
· 1kg/aluminium foil bag, with two plastic bags inside.
· 25kg/fiber drum, with two plastic bags inside.
Size:ID 42cm*H52cm,0.08m3/drum;
Net Weight:25kgs Gross Weight:28kgs.

Delivery- ≤50kg, Express delivery recommended, usually called as DDU service;
- ≤500kg,Air shipping recommended, usually called as CIF service;
- >500kg, sea shipping recommended, usually called as FOB, CFR, or CIF service;
- For high value products, please select air shipping and express delivery for safety.
About us
Shandong Zhishang Chemical Co.,Ltd owned by Zhishang International Group,is a new chemical enterprise with R&D.
manufacture and sales department.
Our company mainly produce pharmaceutical raw materials and intermediate(expecially Carbohydrate derivatives series).
In recent years,we had made big breakthrough in feed additive,plant extraction,industrial chemicals line.
With our "Honest operation,Quality controlling,Clients first"theory,our company enjoy good repute both home and abroad.
The R&D center located in High-tech zone in Jinan,our production based is in Chemical park of Zhangqiu and Tai'an.Our production process strictly conform with ISO 9001 and ISO 2000 standard.Our lab and workshop also follows strictly with GMP standard.Our products are sold all over Europe,North&South America, Sino-East, Asia and pacific area as well as Africa,we establish long term and stable business relations.We have large scale liquid chemical terminal and professional chemical warehouse.
We will always adhere to expand business scope and provide the best quality products and service to the world.


- DO YOU ACCEPT SAMPLE ORDER?
We accept sample orders. We will make samples before mass production, and after sample approved, we'll begin mass production. Doing 100% inspection during production, then do random inspection before packing.
2.HOW TO CONFIRM THE PRODUCT QUALITY BEFORE PLACING ORDERS?
You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests,we will manufacture the products according to your requests.
3.WHAT'S YOUR MOQ?
Our MOQ is 1kg. But usually we accept less quantity such as 100g on the condition that sample charge is 100% paid.
4.DO YOU SUPPLY PRODUCT REPORT?
Yes. We'll give you product analysis report before shipping.
5.IS THERE A DISCOUNT?
Different quantity has different discount.
Our Advantage
10 Years Experience
Our products are sold all over Europe,North&South America, Sino-East, Asia and pacific area as well as Africa,we establish long term.
Quality service
Company cooperates with research institutes. We strictly control the process of raw materials up to finished product.
24 hour serviceQuick and clear response to customers questions. Warm after sale service, we will help to solve the problems in your usage.
High quality
Dedicated to serving customers first, we provide reasonable prices, high quality products.ECHEMI Editorial ReferenceDipyridamole (Persantine) is a phosphodiesterase inhibitor that blocks uptake and metabolism of adenosine by erythrocytes and vascular endothelial cells.Target: Phosphodiesterase (PDE)Dipyridamole concentrations of 1 nmol/ml blood caused 90% inhibition of adenosine metabolism. Dipyridamole at therapeutic concentrations causes significant inhibition of adenosine metabolism in whole blood [1]. Dipyridamole has a dose-dependent inhibitory effect on thromboxane synthesis which was independen
Solid
Dipyridamole is a pyrimidopyrimidine that is 2,2',2'',2'''-(pyrimido[5,4-d]pyrimidine-2,6-diyldinitrilo)tetraethanol substituted by piperidin-1-yl groups at positions 4 and 8 respectively. A vasodilator agent, it inhibits the formation of blood clots. It has a role as an adenosine phosphodiesterase inhibitor, an EC 3.5.4.4 (adenosine deaminase) inhibitor, a platelet aggregation inhibitor and a vasodilator agent. It is a member of piperidines, a pyrimidopyrimidine, a tertiary amino compound and a tetrol.|A phosphodiesterase inhibitor that blocks uptake and metabolism of adenosine by erythrocytes and vascular endothelial cells. Dipyridamole also potentiates the antiaggregating action of prostacyclin. (From AMA Drug Evaluations Annual, 1994, p752)|Dipyridamole is a Platelet Aggregation Inhibitor. The physiologic effect of dipyridamole is by means of Decreased Platelet Aggregation.|Dipyridamole is a vasodilator and inhibitor of platelet aggregation that is used to decrease the risk of thromboembolic complications and recurrence of stroke in patients known to have atherosclerotic cerebrovascular disease. Dipyridamole is associated with a low rate of serum enzyme elevations during treatment, but has not been linked to instances of clinically apparent acute liver injury.|Dipyridamole is a synthetic agent derivative of pyrimido-pyrimidine, with antiplatelet properties. Dipyridamole inhibits adenosine uptake by platelets and endothelial cells, triggering an accumulation of cyclic adenosine monophosphate (cAMP), and inhibiting the stimulation of platelet aggregation by agents such as platelet activating factor and collagen. (NCI04)Basic Info-
Product Name:
Dipyridamole
Other Name:Ethanol,2,2′,2′′,2′′′-[(4,8-di-1-piperidinylpyrimido[5,4-d]pyrimidine-2,6-diyl)dinitrilo]tetrakis-;Ethanol,2,2′,2′′,2′′′-[(4,8-dipiperidinopyrimido[5,4-d]pyrimidine-2,6-diyl)dinitrilo]tetra-;Pyrimido[5,4-d]pyrimidine,ethanol deriv.;2,2′,2′′,2′′′-[(4,8-Di-1-piperidinylpyrimido[5,4-d]pyrimidine-2,6-diyl)dinitrilo]tetrakis[ethanol];RA 8;2,6-Bis(diethanolamino)-4,8-dipiperidinopyrimido[5,4-d]pyrimidine;2,2′,2′′,2′′′-[[4,8-Dipiperidinopyrimido(5,4-d)pyrimidine-2,6-diyl]dinitrilo]tetraethanol;Dipyridamine;Dipyridamol;Dipyridamole;Persantin;Persantine;Anginal;Cardoxin;Curantyl;Kurantil;Stenocardil;Apricor;Cardioflux;Stimolcardio;Coribon;Corosan;Coroxin;Prandiol;Coronarine;Cardoxil;Gulliostin;Protangix;Piroan;Peridamol;Natyl;Coridil;Cleridium;NSC 515776;Dipyridan;NSC 619103;2,2′,2′′,2′′′-[[4,8-Di(piperidin-1-yl)pyrimido[5,4-d]pyrimidine-2,6-diyl]dinitrilo]tetraethanol;2,2′,2′′,2′′′-((4,8-Di(piperidin-1-yl)pyrimido[5,4-d]pyrimidine-2,6-diyl)bis(azanetriyl))tetraethanol;2-([6-[Bis(2-hydroxyethyl)amino]-4,8-bis(piperidin-1-yl)-[1,3]diazino[5,4-d]pyrimidin-2-yl](2-hydroxyethyl)amino)ethan-1-ol;2-[[2-[Bis(2-hydroxyethyl)amino]-4,8-di(piperidin-1-yl)pyrimido[5,4-d]pyrimidin-6-yl]-(2-hydroxyethyl)amino]ethanol
CAS No.:58-32-2
Molecular Formula:C24H40N8O4
InChIKeys:InChIKey=IZEKFCXSFNUWAM-UHFFFAOYSA-N
Molecular Weight:504.63
Exact Mass:504.63
EC Number:200-374-7
UNII:64ALC7F90C
NSC Number:756743|619103|515776
DSSTox ID:DTXSID6040668
NCI Thesaurus Code:C445
ATC Code:B - Blood and blood forming organs
HScode:2933990090
Categories:
Characteristics-
PSA:
145
XLogP3:0.7
Appearance:yellow powder
Density:1.4±0.1 g/cm3
Melting Point:163 °C
Boiling Point:806.5°C at 760 mmHg
Flash Point:441.5±37.1 °C
Refractive Index:1.670
Water Solubility:soluble in chloroform, methanol, dilute acids, ethanol. Slightly soluble in water.DMSO: soluble
Storage Conditions:−20°C
Toxicity:LD50 in rats: 8.4 g/kg orally; 208 mg/kg i.v. (Takenaka)
Collision Cross Section:227.5 Ų [M+H]+ [CCS Type: TW, Method: Major Mix IMS/Tof Calibration Kit (Waters)]|223.9 Ų [M+H]+ [CCS Type: TW, Method: calibrated with polyalanine and drug standards]
Hazard IdentificationClassification of the substance or mixture
Skin irritation, Category 2
Eye irritation, Category 2
Specific target organ toxicity â single exposure, Category 3
GHS label elements, including precautionary statements
Pictogram(s)
Signal word Warning
Hazard statement(s) H315 Causes skin irritation
H319 Causes serious eye irritation
H335 May cause respiratory irritation
Precautionary statement(s) Prevention P264 Wash ... thoroughly after handling.
P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P271 Use only outdoors or in a well-ventilated area.
Response P302+P352 IF ON SKIN: Wash with plenty of water/...
P321 Specific treatment (see ... on this label).
P332+P317 If skin irritation occurs: Get medical help.
P362+P364 Take off contaminated clothing and wash it before reuse.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing.
P319 Get medical help if you feel unwell.
Storage P403+P233 Store in a well-ventilated place. Keep container tightly closed.
P405 Store locked up.
Disposal P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
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Seller Information
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Business Type:
Manufactory
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Main Products:
Dichloromethane,Linocaine hydrochloride
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Location:
BUILDING 1,HISENSE INTELLIGENCE VALLEY,NO.2116,OF PHOEIX ROAD, HIGH-TECH ZONE ,JINAN CITY ,SHANDONG PROVINCE,CHINA
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Payment Terms:
D/P,L/C,D/A
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Average lead Time:
15
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Total Annual Revenue:
$10 million-$25 million
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Total Employees:
11-50
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Year of Establishment:
2016
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Country Product Purchase Quantity Date Posted Post an enquiry for this product