65002-17-7
65002-17-7
kg
2022-02-06
Custom Synthetic Chemicals,Biological Stains,Pharmaceutical Intermediates,Cosmetic Grade Chemicals,Enzyme,Nucleosides
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Product Description
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Seller Information
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DescriptionECHEMI Editorial ReferenceOff-White Solid
Bucillamine is an organic molecular entity.|Bucillamine has been used in trials studying the treatment and prevention of Gout and Rheumatoid Arthritis.|Bucillamine is an orally bioavailable derivative of the endogenous amino acid cysteine with two donatable thiol groups, with potential antioxidant and anti-inflammatory activities. Upon oral administration, bucillamine enters cells rapidly via the same pathway as cysteine and replenishes the thiol group in glutathione (GSH), thereby increasing intracellular GSH levels and GSH activity. GSH is an antioxidant and plays an important protective role in oxidative stress and injury. Bucillamine may have additional anti-inflammatory effects, though the mechanisms of action have yet to be fully elucidated.Basic Info-
Product Name:
Bucillamine
Other Name:L-Cysteine,N-(2-mercapto-2-methyl-1-oxopropyl)-;N-(2-Mercapto-2-methyl-1-oxopropyl)-L-cysteine;SA 96;N-(2-Mercapto-2-methylpropanoyl)-L-cysteine;N-(2-Mercapto-2-methylpropionyl)-L-cysteine;Thiobutarit;N-(2-Mercaptoisobutyryl)cysteine;Bucillamine;Tiobutarit;Rimatil;DE 019;(2R)-2-(2-Methyl-2-sulfanylpropanamido)-3-sulfanylpropanoic acid;(R)-3-Mercapto-2-(2-mercapto-2-methylpropanamido)propanoic acid
CAS No.:65002-17-7
Molecular Formula:C7H13NO3S2
InChIKeys:InChIKey=VUAFHZCUKUDDBC-BYPYZUCNSA-N
Molecular Weight:223.31
Exact Mass:223.31
UNII:R80LRA5WTF
DSSTox ID:DTXSID2048587
NCI Thesaurus Code:C83561
ATC Code:M - Musculo-skeletal system
HScode:2930909090
Categories:
Characteristics-
PSA:
68.4
XLogP3:1.28
Density:1.3±0.1 g/cm3
Melting Point:139-140 °C
Boiling Point:438.0±45.0 °C at 760 mmHg
Flash Point:218.7±28.7 °C
Refractive Index:1.553
Storage Conditions:Hygroscopic, -20°C Freezer, Under Inert Atmosphere
Toxicity:LD50 in mice (mg/kg): 2285 i.p.; 989.6 i.v. (Fujita, 1981)
Specific rotation:D25 +32.3° (c = 1.0 in ethanol)
Hazard IdentificationClassification of the substance or mixture
no data available
GHS label elements, including precautionary statements
Pictogram(s) no data available Signal word no data available
Hazard statement(s) no data available
Precautionary statement(s) Prevention no data available
Response no data available
Storage no data available
Disposal no data available
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
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Seller Information
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Business Type:
Manufactory
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Main Products:
Custom Synthetic Chemicals,Biological Stains,Pharmaceutical Intermediates,Cosmetic Grade Chemicals,Enzyme,Nucleosides
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Location:
Room 308-80, building 1, 1963 Huaguan Road, Tianhe District, Guangzhou
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Payment Terms:
TT against copy of documents,D/P,L/C,D/A,O/A,100% TT in advance
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Average lead Time:
30 days
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Total Annual Revenue:
$5 million-$10 million
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Total Employees:
51-100
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Year of Establishment:
2021
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Country Product Purchase Quantity Date Posted Post an enquiry for this product
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