Etodolac >=99.0% Pharmaceutical API made in china
41340-25-4
2026-09-24
D-Biotin,Tobramycin base,L(-)-Carnitine base,Polymyxin B sulfate USP,Kanamycin sulfate monohydrate,Finasteride 99% USP
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Product Description
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Seller Information
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DescriptionHangzhou Dawn Ray Pharmaceutical Co.,Ltd, with approximately 67642 visits to its shop, is a reputable Manufactory that has been providing Etodolac >=99.0% Pharmaceutical API made in china products for 5 years on ECHEMI.ECHEMI Editorial ReferenceEtodolac is a non-steroidal anti-inflammatory compound that is a non-selective inhibitor of COX (IC50=53.5 nM)IC50 value: 53.5 nMTarget: COX1; COX2Post-marketing studies demonstrated that etodolac inhibition of cyclooxygenase is somewhat COX-2 selective similar to celecoxib and other "COX-2 inhibitors." Unlike rofecoxib, both etodolac and celecoxib can fully inhibit COX-1 and are designated as having "preferential selectivity" toward COX-2. The (inactive against COX) r-enantiomer of etod
Solid
Etodolac is a monocarboxylic acid that is acetic acid in which one of the methyl hydrogens is substituted by a 1,8-diethyl-1,3,4,9-tetrahydropyrano[3,4-b]indol-1-yl moiety. A preferential inhibitor of cyclo-oxygenase 2 and non-steroidal anti-inflammatory, it is used for the treatment of rheumatoid arthritis and osteoarthritis, and for the alleviation of postoperative pain. Administered as the racemate, only the (S)-enantiomer is active. It has a role as a non-steroidal anti-inflammatory drug, a cyclooxygenase 2 inhibitor, a non-narcotic analgesic and an antipyretic. It is a monocarboxylic acid and an organic heterotricyclic compound.|Etodolac is a non-steroidal anti-inflammatory drug (NSAID) with anti-inflammatory, analgesic and antipyretic properties. Its therapeutic effects are due to its ability to inhibit prostaglandin synthesis. It is indicated for relief of signs and symptoms of rheumatoid arthritis and osteoarthritis.|Etodolac is a nonsteroidal antiinflammatory drug (NSAID) that is available by prescription only and is used long term for therapy of chronic arthritis and short term for acute pain. Etodolac has been linked to rare instances of clinically apparent drug induced liver disease.|A non-steroidal anti-inflammatory agent and cyclooxygenase-2 (COX-2) inhibitor with potent analgesic and anti-arthritic properties. It has been shown to be effective in the treatment of OSTEOARTHRITIS; RHEUMATOID ARTHRITIS; ANKYLOSING SPONDYLITIS; and in the alleviation of postoperative pain (PAIN, POSTOPERATIVE).Basic Info-
Product Name:
Etodolac
Other Name:Pyrano[3,4-b]indole-1-acetic acid,1,8-diethyl-1,3,4,9-tetrahydro-;1,8-Diethyl-1,3,4,9-tetrahydropyrano[3,4-b]indole-1-acetic acid;Etodolic acid;AY 24236;Etodolac;NIH 9918;(±)-Etodolac;(RS)-Etodolic acid;Lodine;Zedolac;Ultradol;Tedolan;Ramodar;Edolan;NSC 282126;Etogesic;Lodin XL;Napilac;Etodine;Eccoxolac;1,8-Diethyl-1,3,4,9-tetrahydropyrano[3,4-b]indol-1-acetic acid;Flancox;Etopan;2-(1,8-Diethyl-4,9-dihydro-3H-pyrano[3,4-b]indol-1-yl)acetic acid;87226-38-8
CAS No.:41340-25-4
Molecular Formula:C17H21NO3
InChIKeys:InChIKey=NNYBQONXHNTVIJ-UHFFFAOYSA-N
Molecular Weight:287.35
Exact Mass:287.35
EC Number:1312995-182-4
NSC Number:757821|282126
DSSTox ID:DTXSID9020615
ATC Code:M - Musculo-skeletal system
HScode:2934999090
Categories:
Characteristics-
PSA:
62.3
XLogP3:2.8
Appearance:crystalline solid
Density:1.2±0.1 g/cm3
Melting Point:146.5 °C
Boiling Point:507.9ºC at 760 mmHg
Flash Point:261.0±28.7 °C
Refractive Index:1.597
Water Solubility:40mg/L(37 ºC)
Storage Conditions:2-8°C
Dissociation Constants:4.65
Collision Cross Section:164.4 Ų [M+H]+ [CCS Type: TW, Method: calibrated with polyalanine and drug standards]
Hazard IdentificationClassification of the substance or mixture
Acute toxicity - Category 3, Oral
Eye irritation, Category 2
GHS label elements, including precautionary statements
Pictogram(s) 
Signal word Danger
Hazard statement(s) H301 Toxic if swallowed
H319 Causes serious eye irritation
Precautionary statement(s) Prevention P264 Wash ... thoroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...
Response P301+P316 IF SWALLOWED: Get emergency medical help immediately.
P321 Specific treatment (see ... on this label).
P330 Rinse mouth.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
Storage P405 Store locked up.
Disposal P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
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Seller Information
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Business Type:
Manufactory
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Main Products:
D-Biotin,Tobramycin base,L(-)-Carnitine base,Polymyxin B sulfate USP,Kanamycin sulfate monohydrate,Finasteride 99% USP
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Location:
1613 Guangyin Building,No.42 E.Fengqi Road,Hangzhou,310012 China.
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Payment Terms:
TT against copy of documents,L/C
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Average lead Time:
7
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Total Annual Revenue:
$25 million-$50 million
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Total Employees:
11-50
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Year of Establishment:
2011
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