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Home > Active Pharmaceutical Ingredients > Digestive System Drugs > Obeticholic acid for Sale > Obeticholic Acid 98% white powder Xieli
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Obeticholic Acid 98% white powder  Xieli buy - image1

Obeticholic Acid 98% white powder Xieli

Unit Price: Get Latest Price
CAS No.:

459789-99-2

Grade:

Pharmaceutical Grade

Content:

98%

Brand:

Xieli

Packaging:

according to customer requirement

Price valid (until):

2023-06-03

Company Type:
Manufactory
Location:
China
Qualification:
Main Products:

dasatinib,ingenol mebutate,hesperidin,irinotecan HCL,erlotinib,nastrozole

  • Product Description

  • Seller Information

  • Description
    ItemsSpecifications
    AppearanceWhite powder
    Molecular FormulaC26H44O4
    Melting Point 108-110 °C
    CAS459789-99-2

    Introduction of Obeticholic Acid

    Obeticholic acid, also known as 6-ethyl chenodeoxycholic acid, is a new derivative of chenodeoxycholic acid (CDCA) in human primary bile acids. It is a natural ligand of farneside derivative X receptor (FXR). Obecholic acid is a farnesol X receptor agonist, which indirectly inhibits the gene expression of cytochrome 7a1 (CYP7A1) by activating farnesol X receptor. Because CYP7A1 is the rate limiting enzyme of cholic acid biosynthesis, OBE cholic acid can inhibit cholic acid synthesis and be used to treat primary biliary cirrhosis and nonalcoholic fatty liver disease


    About us

    Xieli Pharm was Founded in 1980's as professional manufacturer on oncology& Animal/botanical derivative APIs and CMO services, with cGMP\ EU GMP\ Japan GMP certified factory and independent R& D center. R& D team with rich experience in process development in R& D, process scale-up and production, and succeed to finish many CMO projects. RA team with rich experience for global registration. DMF including 17 products registered in 100+ countries and submission 500+ times. Irinotecan certificated with Japan GMP and EU GMP. Rutin and Troxerutin certificated with EU-GMP; CEP for Diosmin & Troxerutin& Irinotecan HCl& Gefitinib& Anastrozole. OEM for plant extracting and TCM Processing. CDMO for Process Development, Intermidate, APIs, Formulation and Clinic Study.

    Basic Info
    Product Name:

    Obeticholic acid

    Other Name:

    Cholan-24-oic acid,6-ethyl-3,7-dihydroxy-,(3α,5β,6α,7α)-;(3α,5β,6α,7α)-6-Ethyl-3,7-dihydroxycholan-24-oic acid;6-Ethylchenodeoxycholic acid;3α,7β-Dihydroxy-6α-ethyl-5β-cholan-24-oic acid;Obeticholic acid;INT 747;6α-Ethylchenodeoxycholic acid;6-ECDCA;Ocaliva

    CAS No.:

    459789-99-2

    Molecular Formula:

    C26H44O4

    InChIKeys:

    InChIKey=ZXERDUOLZKYMJM-ZWECCWDJSA-N

    Molecular Weight:

    420.63

    Exact Mass:

    420.63

    UNII:

    0462Z4S4OZ

    DSSTox ID:

    DTXSID20196671

    NCI Thesaurus Code:

    C80837

    ATC Code:

    A05AA04|A - Alimentary tract and metabolism

    Characteristics
    PSA:

    77.8

    XLogP3:

    5.7

    Density:

    1.091

    Melting Point:

    108-110 °C

    Boiling Point:

    562.9°C at 760 mmHg

    Flash Point:

    308.3±19.7 °C

    Refractive Index:

    1.530

    PKA:

    4.76±0.10

    Dissociation Constants:

    4.76±0.10

    Hazard Identification

    Classification of the substance or mixture

    Reproductive toxicity, Category 2

    GHS label elements, including precautionary statements

    Pictogram(s)
    Signal word

    Warning

    Hazard statement(s)

    H361 Suspected of damaging fertility or the unborn child

    Precautionary statement(s)
    Prevention

    P203 Obtain, read and follow all safety instructions before use.

    P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...

    Response

    P318 IF exposed or concerned, get medical advice.

    Storage

    P405 Store locked up.

    Disposal

    P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

    Other hazards which do not result in classification

    no data available

    Handling and Storage

    Precautions for safe handling

    Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

    Conditions for safe storage, including any incompatibilities

    Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

  • Seller Information
    Business Type:

    Manufactory

    Main Products:

    dasatinib,ingenol mebutate,hesperidin,irinotecan HCL,erlotinib,nastrozole

    Location:

    NO.588, middle section of mudan avenue

    Payment Terms:

    TT against copy of documents,L/C

    Average lead Time:

    15

    Total Annual Revenue:

    Above $100 million

    Total Employees:

    501-1000

    Year of Establishment:

    1992

    Company Profile
    Xieli Pharm was founded in 1980's with cGMP\ EU GMP\ Japan GMP certified factory and independent R&D center. Irinotecan certificated with Japan GMP and EU GMP. Rutin and Troxerutin certificated with EU-GMP; CEP for Diosmin and Troxerutin OEM for plant extracting and TCM Processing CDMO for Process Development, Intermidate, APIs, Formulation and Clinic Study.
  • Country Product Purchase Quantity Date Posted
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