Diphenhydramine, PM-255, PM 255, pm255 99% white powder 58-73-1 Senwayer

Diphenhydramine, an antihistamine. It has the effect of antihistamine H1 receptor, has a strong inhibitory effect on the central nervous system, and has atropine-like effect. It is suitable for allergic diseases of skin and mucous membranes, such as urticaria, hay fever, allergic rhinitis, etc. It can also be used to prevent motion sickness such as seasickness, motion sickness, and plane sickness. Drowsiness and dry mouth are the main adverse reactions.

Diphenhydramine is an antihistamine that reduces the effects of natural chemical histamine in the body. Histamine can produce symptoms of sneezing, itching, watery eyes, and runny nose.

Diphenhydramine is used to treat sneezing, runny nose, watery eyes, hives, skin rash, itching, and other cold or allergy symptoms.

Diphenhydramine is also used to treat motion sickness, to induce sleep, and to treat certain symptoms of Parkinson's disease.

1. Allergies to the skin and mucous membranes, such as urticaria, angioedema, allergic rhinitis, other skin pruritus, anal pruritus, genital pruritus, drug eruption or jaundice, it is also effective for insect bites and contact dermatitis ;
2. Acute allergic reaction, which can reduce the allergic reaction caused by blood transfusion or plasma; antihistamine drugs such as diphenhydramine are often used before blood transfusion, usually 40 mg of diphenhydramine is given intramuscularly, and attention is paid to the screening of blood donors , try not to use blood donors with a history of allergies. Avoid repeated transfusion of the blood of the same donor to avoid antigen-antibody reaction. If there is anti-IgA antibody in the blood recipient, the washed red blood cells can be transfused. This washing method can remove the IgA in the blood of the donor. to prevent allergic reactions.
3. The prevention and treatment of motion sickness and seasickness has a strong antiemetic effect, and can also be used to prevent and treat radiation sickness, vomiting after surgery, and nausea and vomiting caused by drugs;
4. For Parkinson's disease and extrapyramidal symptoms;
5. Sedation, used for hypnosis and preoperative administration;
6. Dental local anesthesia. When the patient is highly allergic to commonly used local anesthetics, 1% diphenhydramine solution can be used as a dental local anesthetic;
7. Antitussive, as a non-addictive cough medicine, it is suitable for treating cough caused by cold or allergy, but its antitussive effect has not been confirmed.

Get emergency medical help if you have any signs of an allergic reaction to diphenhydramine: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Stop using diphenhydramine and call your doctor at once if you have:

• pounding heartbeats or fluttering in your chest;

• painful or difficult urination;

• little or no urinating;

• confusion, feeling like you might pass out; or

• tightness in your neck or jaw, uncontrollable movements of your tongue.

Common diphenhydramine side effects may include:

• dizziness, drowsiness, loss of coordination;

• dry mouth, nose, or throat;

• constipation, upset stomach;

• dry eyes, blurred vision; or

• day-time drowsiness or "hangover" feeling after night-time use.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.

• Documented hypersensitivity to diphenhydramine
• Premature infants and neonates
• Breastfeeding mothers
• Pregnancy Category B - used only if clearly needed
• Diphenhydramine has additive effects with alcohol and other CNS depressants (hypnotics, sedatives, tranquilizers)
• Monoamine oxidase A inhibitors prolong and intensify the anticholinergic effects of antihistamines

Wuhan senwayer century chemical Co.,Ltd located in the predominant WuHan City where is a traffic hinge of China,specilize in producing and developing pharmaceutical & its intermediates, Pesticide Intermediate, food additive, Plant extracts,and in distributing the products of our own company and affiliated enterprises.

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