High Quality Intermediates Candesartan CAS: 139481-59-7
ISO 1 Inquiries
139481-59-7
0%
100g;1kg;25g
2022-12-31
Agrochemicals,Daily Chemicals,Catalysts & Chemical Auxiliary Agents,Extract,Inorganic Chemicals,Organic Intermediate
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Product Description
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Seller Information
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Inquiry History
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Description
Melting point 183-185°C Boiling point 754.8±70.0 °C(Predicted) density 1.41±0.1 g/cm3(Predicted) RTECS DD6671000 storage temp. Inert atmosphere,Store in freezer, under -20°C pka 2.06±0.10(Predicted) Water Solubility Soluble water (<1 mg/ml at 25°C), DMSO (88 mg/ml at 25°C), and ethanol (1 mg/ml at 25°C). CAS DataBase Reference 139481-59-7(CAS DataBase Reference)
Product description:Candesartan, a prodrug of candesartan cilexetil, is a new type of rapid development after angiotensin-converting enzyme inhibitor (ACEI) that acts on the renin-angiotensin system (RAS) medicine.
Packing
· 1kg/aluminium foil bag, with two plastic bags inside.
· 25kg/fiber drum, with two plastic bags inside.
Size:ID 42cm*H52cm,0.08m3/drum;
Net Weight:25kgs Gross Weight:28kgs.
Delivery- ≤50kg, Express delivery recommended, usually called as DDU service;
- ≤500kg,Air shipping recommended, usually called as CIF service;
- >500kg, sea shipping recommended, usually called as FOB, CFR, or CIF service;
- For high value products, please select air shipping and express delivery for safety.
SHANDONG LOOK CHEMICAL CO.LTD, a new chemical enterprise in researching, manufacturing and supplying of chemicals located in beautiful "Spring City"-Jinan.Our company mainly working on the researching new-born APIs, intermediate ( especially Carbohydrate derivatives series). Meanwhile, we made huge breakthrough in industries of food, feed additives, cosmetics ,dye and industrial chemicals. Our company enjoyed great reputation both domestic and abroad under the belief of "Integrity management,Quality controlling and Customer orientation".
We had been cooperated with NingXia University and Shandong University on more than ten projects for years and which had been in mass production on the market. We now have more than 80 people in our team and built research center in Jinan and Ningxia. Our manufacturing site allocated in chemical industry parks of Zhangqiu, Heze, Dezhou and Ningxia Fine Chemical Park. We strictly complying with ISO9001 and ISO 2000 standard in manufacturing process, our lab and workshop tightly in accordance with GMP standard.Our products best selling in Europe, South and North America,Asia pacific area and Africa. We sincerely welcome new and regular customers around the world visit us for business negotiation.
FAQ- DO YOU ACCEPT SAMPLE ORDER?
We accept sample orders. We will make samples before mass production, and after sample approved, we'll begin mass production. Doing 100% inspection during production, then do random inspection before packing.
2.HOW TO CONFIRM THE PRODUCT QUALITY BEFORE PLACING ORDERS?
You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests,we will manufacture the products according to your requests.
3.WHAT'S YOUR MOQ?
Our MOQ is 1kg. But usually we accept less quantity such as 100g on the condition that sample charge is 100% paid.
4.DO YOU SUPPLY PRODUCT REPORT?
Yes. We'll give you product analysis report before shipping.
5.IS THERE A DISCOUNT?
Different quantity has different discount.
Our Advantage
10 Years Experience
Our products are sold all over Europe,North&South America, Sino-East, Asia and pacific area as well as Africa,we establish long term.
Quality service
Company cooperates with research institutes. We strictly control the process of raw materials up to finished product.
24 hour serviceQuick and clear response to customers questions. Warm after sale service, we will help to solve the problems in your usage.
High quality
Dedicated to serving customers first, we provide reasonable prices, high quality products.ECHEMI Editorial ReferenceCrystalline SolidChEBI: A benzimidazolecarboxylic acid that is 1H-benzimidazole-7-carboxylic acid substituted by an ethoxy group at position 2 and a ({2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl}methyl) group at position 1. It is a angiotensin eceptor antagonist used for the treatment of hypertension.Candesartan, (+)-1-[[(cyclohexyloxy)carbonyl]-oxy]ethyl 2- ethoxy-1-[[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-1H-benzimidazole-7-carboxylate(Atacand), like losartan, possesses the acidicCertificatesBasic Info-
Product Name:
Candesartan
Other Name:1H-Benzimidazole-7-carboxylic acid,2-ethoxy-1-[[2′-(2H-tetrazol-5-yl)[1,1′-biphenyl]-4-yl]methyl]-;1H-Benzimidazole-7-carboxylic acid,2-ethoxy-1-[[2′-(1H-tetrazol-5-yl)[1,1′-biphenyl]-4-yl]methyl]-;2-Ethoxy-1-[[2′-(2H-tetrazol-5-yl)[1,1′-biphenyl]-4-yl]methyl]-1H-benzimidazole-7-carboxylic acid;CV 11974;Candesartan;Candesartan M1;2-Ethoxy-1-[[2′-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl]-1H-benzimidazole-7-carboxylic acid;2-Ethoxy-1-[[2′-(1H-tetrazol-5-yl)-1,1′-biphenyl-4-yl]methyl]-7-benzimidazolecarboxylic acid;2-Ethoxy-1-[[2′-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl]benzimidazole-7-carboxylic acid;3-[[2′-(1H-Tetrazol-5-yl)biphenyl-4-yl]methyl]-2-ethoxy-3H-benzimidazole-4-carboxylic acid;1-((2′-(1H-Tetrazol-5-yl)-[1,1′-biphenyl]-4-yl)methyl)-2-ethoxy-1H-benzo[d]imidazole-7-carboxylic acid;2-Ethoxy-1-([4-[2-(1H-1,2,3,4-tetrazol-5-yl)phenyl]phenyl]methyl)-1H-1,3-benzodiazole-7-carboxylic acid;875515-04-1
CAS No.:139481-59-7
Molecular Formula:C24H20N6O3
InChIKeys:InChIKey=HTQMVQVXFRQIKW-UHFFFAOYSA-N
Molecular Weight:440.45
Exact Mass:440.45
EC Number:1806241-263-5
UNII:S8Q36MD2XX
NSC Number:759858
DSSTox ID:DTXSID0022725
NCI Thesaurus Code:C65284
Color/Form:Colorless crystals from ethyl acetate + methanol
ATC Code:C - Cardiovascular system
HScode:29419000
Categories:
Characteristics-
PSA:
119
XLogP3:4.1
Appearance:Solid
Density:1.41±0.1 g/cm3(Predicted)
Melting Point:183-185 °C
Boiling Point:754.8±70.0 °C(Predicted)
Flash Point:410.3±35.7 °C
Refractive Index:1.719
Water Solubility:soluble in ethyl acetate, methanol, water (<1 mg/ml at 25°C), DMSO (88 mg/ml at 25°C), and ethanol (1 mg/ml at 25°C).
Storage Conditions:-20°C Freezer
Vapor Pressure:1.8X10-18 mm Hg at 25 deg C (est)
Henrys Law Constant:Henry's Law constant = 8.7X10-19 atm-cu m/mol at 25 °C (est)
Dissociation Constants:pKa1 = 2.45 (carboxylic acid); pKa2 = 6.70 (N-heterocyclic) (est)
Experimental Properties:Colorless crystals from ethanol + water, mp 163 °C (decomposes). Also reported as white to off-white powder, sparingly soluble in methanol. Practically insoluble in water. /Candesartan 1-[[(Cyclohexyloxy)carbonyl]oxy]ethyl ester/|White to off-white powder, mw - 610.67. Practically insoluble in water and sparingly soluble in methanol. ... a racemic mixture containing one chiral center at the cyclohexyloxycarbonyloxy ethyl ester group. Following oral administration ... undergoes hydrolysis at the ester link to form the active drug, candesartan, which is achiral. /Cilexetil/|White, or practically white, crystalline powder, mw - 297.72 .. Slightly soluble in water, but freely soluble in hydroxide solution /Cilexetil hydrochlorothiazide/|Hydroxyl radical reaction rate constant = 4.96X10-11 cu cm/molec-sec at 25 °C (est)
Hazard IdentificationClassification of the substance or mixture
Reproductive toxicity, Category 2
GHS label elements, including precautionary statements
Pictogram(s) 
Signal word Warning
Hazard statement(s) H361 Suspected of damaging fertility or the unborn child
Precautionary statement(s) Prevention P203 Obtain, read and follow all safety instructions before use.
P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...
Response P318 IF exposed or concerned, get medical advice.
Storage P405 Store locked up.
Disposal P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
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Seller Information
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Business Type:
Manufactory
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Main Products:
Agrochemicals,Daily Chemicals,Catalysts & Chemical Auxiliary Agents,Extract,Inorganic Chemicals,Organic Intermediate
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Location:
hisense intelligence valley,no 2116,of phoenix road
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Payment Terms:
TT against copy of documents,D/P,L/C
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Average lead Time:
7
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Total Annual Revenue:
Less than $1 million
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Total Employees:
11-50
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Year of Establishment:
2017
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Inquiry History1 Inquiries
Country Product Purchase Quantity Date Posted 
India
Candesartan
2000 KG May 26, 2025 Post an enquiry for this product
