Nolatrexed dihydrochloride
152946-68-4
industrial Grade
98%
SHANGHAI
KieRay Chem
25kg/drum
2022-12-31
fine chemicals,pharmaceutical materials
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Product Description
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Seller Information
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DescriptionECHEMI Editorial ReferenceNolatrexed Dihydrochloride is the dihydrochloride salt of nolatrexed, a water-soluble lipophilic quinazoline folate analog with antineoplastic activity. Nolatrexed occupies the folate binding site of thymidylate synthase, resulting in inhibition of thymidylate synthase activity and thymine nucleotide synthesis with subsequent inhibition of DNA replication, DNA damage, S-phase cell cycle arrest, and caspase-dependent apoptosis. This agent also exhibits radiosensitizing activity.Basic Info
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Product Name:
Nolatrexed dihydrochloride
Other Name:4(1H)-Quinazolinone,2-amino-6-methyl-5-(4-pyridinylthio)-,hydrochloride (1:2);4(1H)-Quinazolinone,2-amino-6-methyl-5-(4-pyridinylthio)-,dihydrochloride;AG 337;Nolatrexed dihydrochloride;Thymitaq
CAS No.:152946-68-4
Molecular Formula:C14H12N4OS.2ClH
InChIKeys:InChIKey=PJKVJJYMWOCLIJ-UHFFFAOYSA-N
Molecular Weight:357.3
Exact Mass:356.0265376
UNII:1XA69O733O
DSSTox ID:DTXSID4046810
NCI Thesaurus Code:C1577
Categories:
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Seller Information
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Business Type:
Manufactory
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Main Products:
fine chemicals,pharmaceutical materials
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Location:
Room 260, Building 3, No. 76 Xingqiao North Road, Xingqiao Street, Yuhang District, Hangzhou City, Zhejiang Province, China
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Payment Terms:
TT against copy of documents,L/C
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Average lead Time:
15
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Total Annual Revenue:
$1 million-$2.5 million
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Total Employees:
11-50
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Year of Establishment:
2020
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