Nolatrexed dihydrochloride
152946-68-4
99%
Bottle,barrel,cargo,container,etc.
2026-10-14
Intermediates,Building blocks,API,Silicones,Peptides,Lab chemicals
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Product Description
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Seller Information
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DescriptionKeywords
152946-68-4
Nolatrexed dihydrochloride
C14H12N4OS.2(HCl)
Quick DetailsProName:Nolatrexed dihydrochloride
CasNo:152946-68-4
Molecular Formula:C14H12N4OS.2(HCl)
Appearance:powder, or liquid
Application:Pharmaceuticals, intermediates, APIs, custom synthesis, chemicals
DeliveryTime:5-7 Days
PackAge:Bottle, barrel, cargo, container, etc.
Port:Shanghai
Purity:99
Storage:Stored in room temperature, ventilated place
Transportation:By air, ship, express, etc.
LimitNum:0
Grade:Industrial Grade
SuperiorityBest Seller, High Quality, Competitive Price, Fast Delivery, Quick Response
DetailsLEAPChem supplies high quality Pharmaceuticals, intermediates, APIs, custom synthesis, fine chemicals and other industrial chemicalsECHEMI Editorial ReferenceNolatrexed Dihydrochloride is the dihydrochloride salt of nolatrexed, a water-soluble lipophilic quinazoline folate analog with antineoplastic activity. Nolatrexed occupies the folate binding site of thymidylate synthase, resulting in inhibition of thymidylate synthase activity and thymine nucleotide synthesis with subsequent inhibition of DNA replication, DNA damage, S-phase cell cycle arrest, and caspase-dependent apoptosis. This agent also exhibits radiosensitizing activity.
Tan SolidBasic Info-
Product Name:
Nolatrexed dihydrochloride
Other Name:Nolatrexed hydrochloride;Nolatrexed (AG-337);3,4-Dihydro-2-amino-6-methyl-4-oxo-5-(4-pyridylthio)-quinazoline dihydrochloride Nolatrexed (AG-337);Nolatrexed dihydrochloride 3,4-Dihydro-2-amino-6-methyl-4-oxo-5-(4-pyridylthio)-quinazoline dihydrochloride;Nolatrexed 2hydrochloride;NOLATREXED DIHYDROCHLORIDE;AG 337;2-Amino-6-methyl-5-(4-pyridinylthio)-4(1H)-quinazolinone Hydrochloride
CAS No.:152946-68-4
Molecular Formula:C14H14Cl2N4OS
InChIKeys:PJKVJJYMWOCLIJ-UHFFFAOYSA-N
Molecular Weight:357.26
Exact Mass:356.0265376
EC Number:680-267-3
UNII:1XA69O733O
DSSTox ID:DTXSID4046810
NCI Thesaurus Code:C1577
Color/Form:Off-White to Pale Yellow
Categories:
Characteristics-
Melting Point:
301-3020C
Water Solubility:H2O: 2mg/mL, clear
PKA:4.1; 5.9; 9.8(at 25℃)
Critical Temperature & Pressure:Hygroscopic, -20°C Freezer, Under Inert Atmosphere
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Seller Information
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Business Type:
Trader
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Main Products:
Intermediates,Building blocks,API,Silicones,Peptides,Lab chemicals
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Location:
Room A, 23rd Floor, No. 609 Yan'an Road, Gongshu District, Hangzhou, Zhejiang
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Payment Terms:
TT against copy of documents,D/P,L/C
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Average lead Time:
5
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Total Annual Revenue:
Above $100 million
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Year of Establishment:
2020
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Certifications:
ISO
">Company ProfileLEAPChem is a specialized fine chemical supplier for research, development and production.
LEAPChem provides nearly 200,000 rare and innovative chemical products to support the evolving needs of our customers in research & bulk manufacturing activities.
As a highly customer-oriented enterprise, we are committed to providing high-quality customer services and products to our global customers in a cost-effective and efficient manner.
Our client list includes many major pharmaceutical and science companies, universities, research institutions and chemical catalogue companies.
Methodology: Sound & Stable; Active & Innovative.
Attitude: Conscientious; Ingenious.
Goals: Customer's Satisfaction
We regard client's success as our success.
At LEAPChem, we strive to be the preferred supplier for efficiency increasing and cost lowering in your Research & Production.
To achieve this strategic vision, we always push ourselves to exceed our customer's requirement. By focusing on the aim of 'Beyond Your Expectation', we continually expand our product lines, and enhance our systematic management and human resources.
Welcome to contact us and we look forward to becoming your reliable and preferred partner.
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