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High Purity HPLC Tested CAS 481-49-2 Stephania Japonica Extract 99% Cepharanthine

Name: High Purity HPLC Tested CAS 481-49-2 Stephania Japonica Extract 99% Cepharanthine
Brand: XAZB
SKU: pr2205203602
Price: 4 USD
Availability: InStock

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CAS No.:

481-49-2

Grade:

Daily Chemical/ Food

Content:

99%

Brand:

XAZB

Packaging:

Plastic Bag/ Bottle

Sample Available:

Yes

Price valid (until):

2022-12-31

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Xian ZB Biotech Co.,Ltd

Company Type:

Manufactory

Location:

China

Payment Terms:

TT against copy of documents

Average Lead Time:

8 days

Qualification:

Main Products:

Herb Extracts,Cosmetic raw materails,API

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Product Description
Seller Information

Description

Product name: Cepharanthine

CAS No.: 481-49-2

EINECS: /

Molecular formula:C37H38N2O6

Molecular weight:606.71

Appearance: White to light yellow powder

Melting point: 145-155°

Density: 1.1761 (rough estimate)

Assay: 98% min

Test Method: HPLC

Cepharanthine is an alkaloid extracted from Stephania cephalum and Dibron of the fangchiaceae plant.It has the functions of anti-tumor, anti-malaria, bacteriostasis and regulating immune function. Modern studies suggest that it also has the functions of stimulating reticuloendothelial system, activating hematopoietic tissue and promoting bone marrow hyperplasia. It has been used in clinical prevention and treatment of leukopenia caused by radiotherapy, chemotherapy and other reasons in tumor patients, and has received certain effects. Therefore, cephalotene is considered to be a low toxicity and effective leukocyte - raising drug. The effect of cephalotensin was significantly better than that of the classical reversal drug verapamil, and the cytotoxicity was much less than that of verapamil at the reversal dose. Studies have shown that cephalotene has a good reversal effect on a variety of drug-resistant cells. In vivo, cephalotenin can enhance the immune activity of macrophages and cells.

The latest research shows that Cepharanthine has a strong inhibitory effect on the new coronavirus. A small amount of cepharanthine can prevent the expansion and spread of the new coronavirus.

1. Promoting bone marrow tissue hyperplasia
2. Treating leukocytes decrease and lack caused by cancer chemotherapy and other factors
3. Used for treating thrombocytopenic purpura4. Used for inhibiting pulmonary fibrosis without significant adverse reactions.

1. Applied in food field, it's used as food additive with the function of lengthening life.
2. Applied in health care product field, it is frequently used as health care product supplement or OTCs ingredients and owns good efficacy for treatment of cancer and cardio-cerebrovascular disease.
3. Applied in cosmetics, it can delay aging and prevent UV radiation.
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ECHEMI Editorial Reference

Cepharanthine, an alkaloid derived from Stephania cepharantha Hayata, with possesses anti-inflammatory and antioxidative activities[1][2][3]. Cepharanthine attenuates muscle and kidney injuries induced by limb ischemia/reperfusion (I/R)[3]. Cepharanthine induces autophagy, apoptosis and cell cycle arrest in breast cancer cells[4]. Cepharanthine inhibits the HIV-1 entry process by reducing plasma membrane fluidity[5].
Cepharanthine is a bisbenzylisoquinoline alkaloid from tubers of Stephania; stimulates recovery of immunologic function in lymphatic system after administration of antineoplastic agents or x-irradiation. It is a member of isoquinolines and a bisbenzylisoquinoline alkaloid.

Basic Info

Product Name:

(+)-Cepharanthine

Other Name:

1H-4,6:16,19-Dietheno-21,25-metheno-12H-[1,3]dioxolo[4,5-g]pyrido[2′,3′:17,18][1,10]dioxacycloeicosino[2,3,4-ij]isoquinoline,2,3,13,14,14a,15,26,26a-octahydro-22,30-dimethoxy-1,14-dimethyl-,(14aS,26aR)-;Cepharanthine;Oxyacanthan,6′,12′-dimethoxy-2,2′-dimethyl-6,7-[methylenebis(oxy)]-;(14aS,26aR)-2,3,13,14,14a,15,26,26a-Octahydro-22,30-dimethoxy-1,14-dimethyl-1H-4,6:16,19-dietheno-21,25-metheno-12H-[1,3]dioxolo[4,5-g]pyrido[2′,3′:17,18][1,10]dioxacycloeicosino[2,3,4-ij]isoquinoline;O-Methylcepharanoline;Cepharanthin;1H-4,6:16,19-Dietheno-21,25-metheno-12H-[1,3]dioxolo[4,5-g]pyrido[2′,3′:17,18][1,10]dioxacycloeicosino[2,3,4-ij]isoquinoline,2,3,13,14,14a,15,26,26a-octahydro-22,30-dimethoxy-1,14-dimethyl-,[14aS-(14aR*,26aS*)]-;Cepharantin;(+)-Cepharanthine;NSC 623442;SML 1269;1413-58-7;30255-28-8

CAS No.:

481-49-2

Molecular Formula:

C37H38N2O6

InChIKeys:

InChIKey=YVPXVXANRNDGTA-WDYNHAJCSA-N

Molecular Weight:

606.71

Exact Mass:

606.71

UNII:

7592YJ0J6T

NSC Number:

758965

DSSTox ID:

DTXSID6045957

Categories:

Blood System Drugs

Characteristics

PSA:

61.9

XLogP3:

6.5

Appearance:

Yellow powder.

Density:

1.2±0.1 g/cm3

Melting Point:

140-145 °C

Refractive Index:

1.608

Storage Conditions:

Store cool and dry in sealed containers.

Toxicity:

Oral-rat LD50: 2000 mg/kg; Oral-Mouse LD50: 1900 mg/kg

Flammability characteristics:

Thermal decomposition to emit toxic nitrogen oxide fumes

Specific rotation:

D20 +277° (c = 2 in chloroform)

See More (+)-Cepharanthine Properties 

Hazard Identification

Classification of the substance or mixture

Acute toxicity - Category 4, Oral

GHS label elements, including precautionary statements

Precautionary statement(s)
Pictogram(s)
Signal word	Warning
Hazard statement(s)	H302 Harmful if swallowed
Prevention	P264 Wash ... thoroughly after handling. P270 Do not eat, drink or smoke when using this product.
Response	P301+P317 IF SWALLOWED: Get medical help. P330 Rinse mouth.
Storage	none
Disposal	P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

Other hazards which do not result in classification

no data available

Handling and Storage

Precautions for safe handling

Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Conditions for safe storage, including any incompatibilities

Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

See More (+)-Cepharanthine Safety Data Sheet 

Seller Information

Business Type:
Manufactory

Main Products:
Herb Extracts,Cosmetic raw materails,API

Location:
1403,Jinye B Block

Payment Terms:
TT against copy of documents

Average lead Time:
8 days

Total Annual Revenue:
$2.5 million-$5 million

Total Employees:
11-50

Year of Establishment:
2015

Xian ZB Biotech Co.,Ltd is a leading Manufactory supplier of Arbutin, Nicotinamide, Flucytosine based in Xi'an, Shaanxi, China. With a commitment to quality and customer satisfaction, Xian ZB Biotech Co.,Ltd has become a trusted name in the industry. Our product line includes a range of high-quality Arbutin, Nicotinamide, Flucytosine, which are available at competitive prices. Xian ZB Biotech Co.,Ltd has established itself as a reliable supplier of chemical products on the echemi.com.
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High Purity HPLC Tested CAS 481-49-2 Stephania Japonica Extract 99% Cepharanthine

Product Description

Seller Information

Classification of the substance or mixture

GHS label elements, including precautionary statements

Other hazards which do not result in classification

Precautions for safe handling

Conditions for safe storage, including any incompatibilities

More Choices Find All Products for Sale 

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