Raw Material Nootropic Nefiracetam for Brain Smart CAS 77191-36-7
GMP ISO 1 Inquiries
77191-36-7
99%
XAZB
Foil Bag, Box, Drum
2022-12-31
Herb Extracts,Cosmetic raw materails,API
-
Product Description
-
Seller Information
-
Inquiry History
-
Description
Product DescriptionProduct Name Nefiracetam CAS 77191-36-7 MF C14H18N2O2 MW 246.3 Purity 98% MP 151-155°C BP 458.5°C at 760 mmHg FP 231.1°C Density 1.187g/cm3 Grade Pharmaceutical Grade Appearance White Powder
Nefiracetam belong to the non-marginal Enrichment class of drugs, these drugs have different chemical structures, both through the role of the cerebral cortex to enhance cognitive ability and prevent learning and memory damage. It does not have muscarinic receptor agonist and antagonist properties, does not inhibit the activity of Ach, the drug's anti-amnesic and memory-enhancing effect by increasing the release of cerebral cortex Ach achieved.
Function1. Memory. One of the primary Nefiracetam benefits is better memory and information retention in the long term.
2. Learning Ability. There have been studies showing that this supplement can lead to improvements in spatial learning abilities. Nefiracetam also has a much more potent effect on increasing attention spans, concentration and focus as compared to other nootropics like Pramiracetam, Oxiracetam or Piracetam.
3. Healthy Brain Cells. It may also be helpful in treating patients with cognitive decline as well as improving the health and maintenance of your brain cells. Taking Nefiracetam is thought to actually protect brain neurons from premature cell death due to cytoprotective actions.
4. Stress, Anxiety, Depression. Nefiracetam has been found useful for reducing stress, anxiety, and even depression. The mechanisms of action for these supplements are similar in many respects, but Nefiracetam seems to exhibit a wider range of effects.
5. Seizures. Studies also indicate that this supplement might be effective in treating seizures. This includes both convulsive and non-convulsive seizures. The primary effect is to greatly reduce the effects of amygdala based seizures and use for stroke patients in reducing the number and duration of post-stroke seizures.
6. Alzheimer's and Dementia. May have a therapeutic role in Alzheimer's and Dementia, but this has not been well investigated. Preliminary evidence seems promising
Memory Mechanisms
The memory mechanisms of nefiracetam seem to be linked back to two pathways. One is prolonging the opening of calcium channels which enhances signalling of a receptor independent of the synapse, and the other pathway seems to be tied into PKC and CAMKII which then augments signalling through cholinergic receptors. The former pathway appears to be critical for long-term potentiation, whereas the latter pathway appears to be vital for neuronal signal enhancement.
Some other minor pathways include being a partial agonist at the glycine binding site of the NDMA receptor (may enhance signalling when there are subpar levels of glycine, but attenuates excessive signalling) and increasing affinity of the muscarinic acetylcholine receptors for its ligand, acetylcholine.
CertificatesBasic Info-
Product Name:
Nefiracetam
Other Name:1-Pyrrolidineacetamide,N-(2,6-dimethylphenyl)-2-oxo-;N-(2,6-Dimethylphenyl)-2-oxo-1-pyrrolidineacetamide;DM 9384;DMPPA;Nefiracetam;2-(2-Oxo-1-pyrrolidinyl)-N-(2,6-dimethylphenyl)acetamide;N-(2,6-Dimethylphenyl)-2-(2-oxo-1-pyrrolidinyl)acetamide;Translon;DZL 221;DMMPA
CAS No.:77191-36-7
Molecular Formula:C14H18N2O2
InChIKeys:InChIKey=NGHTXZCKLWZPGK-UHFFFAOYSA-N
Molecular Weight:246.3
Exact Mass:246.30
EC Number:1308068-626-2
UNII:1JK12GX30N
NSC Number:759830
DSSTox ID:DTXSID2020923
HScode:2933790090
Categories:
Characteristics-
PSA:
49.4
XLogP3:1.4
Appearance:white to off-white
Density:1.2±0.1 g/cm3
Melting Point:153 °C
Boiling Point:458.5°C at 760 mmHg
Flash Point:231.1±25.4 °C
Refractive Index:1.594
Water Solubility:DMSO: >5mg/mL
Storage Conditions:Store at RT
Toxicity:LD50 in mice (mg/kg): 421 i.v.; 1766 orally (Betzing, 1982)
Hazard IdentificationClassification of the substance or mixture
Acute toxicity - Category 4, Oral
Eye irritation, Category 2
GHS label elements, including precautionary statements
Pictogram(s) 
Signal word Warning
Hazard statement(s) H302 Harmful if swallowed
H319 Causes serious eye irritation
Precautionary statement(s) Prevention P264 Wash ... thoroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...
Response P301+P317 IF SWALLOWED: Get medical help.
P330 Rinse mouth.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
Storage none
Disposal P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
-
-
Seller Information
-
Business Type:
Manufactory
-
Main Products:
Herb Extracts,Cosmetic raw materails,API
-
Location:
1403,Jinye B Block
-
Payment Terms:
TT against copy of documents
-
Average lead Time:
8
-
Total Annual Revenue:
$2.5 million-$5 million
-
Total Employees:
11-50
-
Year of Establishment:
2015
-
-
Inquiry History1 Inquiries
Country Product Purchase Quantity Date Posted 
United States
Nefiracetam
20 G Jun 5, 2026 Post an enquiry for this product