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High Quality 99% Tofacitinib Citrate for Hair Growth 540737-29-9

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CAS No.:

540737-29-9

Content:

99%

Packaging:

Foil Bag, Box, Drum

Sample Available:

Yes

Price valid (until):

2022-12-31

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Xian ZB Biotech Co.,Ltd

Company Type:

Manufactory

Location:

China

Payment Terms:

TT against copy of documents

Average Lead Time:

8 days

Qualification:

Main Products:

Herb Extracts,Cosmetic raw materails,API

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Product Details
Seller Information
Inquiry History

Description

Product Description

_{Product Name}	_{Tofacitinib citrate}
_CAS	_540737-29-9
_MF	_{C16H20N6O.C6H8O7}
_MW	_504.497
_Appearance	_{White Powder}
_Assay	_99%min
_{Single impurity}	_≤0.1%
_Usage	_{Treat rheumatoid arthritis}
_Dosage	_{30 nM; intraperitoneal injectio}

_{(1).Tofacitinib citrate is a king of drugs developed by the US pharmaceutical company for treating rheumatoid arthritis, for the treatment of methotrexate inadequate response or intolerance to severe active rheumatoid arthritis (RA) in adult patients. Tofacitinib citrate is approved for the treatment of methotrexate inadequate response or intolerance to severe active rheumatoid joints arthritis (RA) in adult patients.

(2). It can be used as monotherapy or in combination with methotrexate or other non-biological disease-modifying antirheumatic drugs (the DMARD) in combination. This medicine should not be in combination with biological DMARD or strong immunosuppressants (such as cyclosporine and azathioprine) . Tofacitinib citrate is approved by the daily dose of 2 times, each time 5mg. Seven clinical trials evaluated the safety and efficacy of Tofacitinib citrate in moderate to severe active RA in adult patients. In all tests, compared with patients receiving placebo, patients receiving Tofacitinib citrate treatment showed significant improvement in clinical response and physical function.abbreviated as NAD+ and NADH respectively.}

Function

_{(1).Tofacitinib citrate is an oral, small molecule drug used to treat adults with moderate-to-severe, active rheumatoid arthritis who have not responded well to being treated with methotrexate. Methotrexate is a disease-modifying antirheumatic drug (DMARD) used to treat rheumatoid arthritis (RA).

(2).Tofacitinib acts to block the body's production of enzymes called Janus kinases (JAKs). JAKs play a role in joint inflammation in RA, which can cause pain, swelling and stiffness. If left untreated, RA inflammation could lead to joint erosions, and organ and tissue damage. It may be used alone or in combination with methotrexate or other DMARDs.}

ECHEMI Editorial Reference

Tofacitinib citrate is a JAK1/2/3 inhibitor with IC50s of 1, 20, and 112 nM, respectively.

Certificates

Basic Info

Product Name:

Tofacitinib citrate

Other Name:

1-Piperidinepropanenitrile,4-methyl-3-(methyl-7H-pyrrolo[2,3-d]pyrimidin-4-ylamino)-β-oxo-,(3R,4R)-,2-hydroxy-1,2,3-propanetricarboxylate (1:1);3-Piperidinamine,1-(cyanoacetyl)-4-methyl-N-methyl-N-1H-pyrrolo[2,3-d]pyrimidin-4-yl-,(3R,4R)-,2-hydroxy-1,2,3-propanetricarboxylate (1:1);Tasocitinib citrate;CP 690500-10;Tofacitinib citrate;CP 690550-10;Xeljanz;Xeljanz XR

CAS No.:

540737-29-9

Molecular Formula:

C16H20N6O.C6H8O7

InChIKeys:

InChIKey=SYIKUFDOYJFGBQ-YLAFAASESA-N

Molecular Weight:

504.497

Exact Mass:

504.196869

EC Number:

1592732-453-0

HScode:

29335990

Categories:

Bulk Drug Intermediates

Characteristics

PSA:

221

XLogP3:

0.23418

Appearance:

white to beige

Melting Point:

201 °C (decomp)

Water Solubility:

DMSO: soluble5mg/mL (clear solution; warmed)

Storage Conditions:

room temp

See More Tofacitinib citrate Properties 

Hazard Identification

Classification of the substance or mixture

Acute toxicity - Category 4, Oral

Reproductive toxicity, Category 1B

GHS label elements, including precautionary statements

Precautionary statement(s)
Pictogram(s)
Signal word	Danger
Hazard statement(s)	H302 Harmful if swallowed H360 May damage fertility or the unborn child
Prevention	P264 Wash ... thoroughly after handling. P270 Do not eat, drink or smoke when using this product. P203 Obtain, read and follow all safety instructions before use. P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...
Response	P301+P317 IF SWALLOWED: Get medical help. P330 Rinse mouth. P318 IF exposed or concerned, get medical advice.
Storage	P405 Store locked up.
Disposal	P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

Other hazards which do not result in classification

no data available

Handling and Storage

Precautions for safe handling

Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Conditions for safe storage, including any incompatibilities

Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

See More Tofacitinib citrate Safety Data Sheet 

Seller Information

Business Type:
Manufactory

Main Products:
Herb Extracts,Cosmetic raw materails,API

Location:
1403,Jinye B Block

Payment Terms:
TT against copy of documents

Average lead Time:
8 days

Total Annual Revenue:
$2.5 million-$5 million

Total Employees:
11-50

Year of Establishment:
2015

Xian ZB Biotech Co.,Ltd is a leading Manufactory supplier of Arbutin, Nicotinamide, Flucytosine based in Xi'an, Shaanxi, China. With a commitment to quality and customer satisfaction, Xian ZB Biotech Co.,Ltd has become a trusted name in the industry. Our product line includes a range of high-quality Arbutin, Nicotinamide, Flucytosine, which are available at competitive prices. Xian ZB Biotech Co.,Ltd has established itself as a reliable supplier of chemical products on the echemi.com.

Inquiry History

4 Inquiries

Country	Product	Purchase Quantity	Date Posted
Austria	Tofacitinib citrate	1 G	Aug 28, 2026
India	Tofacitinib citrate	10 G	Sep 26, 2025
Taiwan, China	Tofacitinib citrate	5 KG	Dec 3, 2025
Canada	Tofactinib citrate	10 G	Mar 21, 2025

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High Quality 99% Tofacitinib Citrate for Hair Growth 540737-29-9

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