Pharmaceutical Raw Material Biapenem CAS 120410-24-4
HALAL ISO FDA 2 Inquiries
120410-24-4
Pharmaceutical Grade
0%
ZB
Foil Bag, Box, Drum
2022-12-31
Herb Extracts,Cosmetic raw materails,API
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Product Description
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Seller Information
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Inquiry History
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Description
English Name: Biapenem
English name: Biapenem
CAS Number: 120410-24-4
Molecular Formula: C15H18N4O4S
Molecular Weight: 350.39
EINECS number: 204-352-8
Related Categories: Antibiotics Antibiotics; API; Chiral; Antibacterial; APIs; Pharmaceutical Intermediates; Peenan Intermediates; Pharmaceutical Intermediates; Chiral Compounds; Intermediates & Fine Chemicals; Pharmaceuticals; Sulfur & Selenium Compounds; Pharmaceutical Intermediate; Pharmaceutical raw material Intermediates
Bipenem is a carbapenem synthetic antibiotic; white salt or off-white powder. Soluble in water, insoluble in common organic solvents. The renal dehydropeptidase is more stable than meropenem and does not require an enzyme inhibitor. Anti-gram-negative bacteria, especially Pseudomonas aeruginosa, are more active than imipenem; antibacterial activity against aerobic gram-positive bacteria is slightly lower than imipenem; the activity of anti-anaerobic bacteria is the same as that of imipenem . Carbapenem antibiotics.
Customers Reviews
ECHEMI Editorial ReferenceOff-White SolidBiapenem was introduced in Japan as a parenteral treatment for bacterial infections. This new 1-β-methylcarbapenem can be prepared by reaction of commercially available 4-nitrobenzyl protected β-methylcarbapenem enolphosphate with mercapto bicyclotriazolium chloride, obtained in 11 steps starting from hydrazine, followed by deprotection of the carboxylic acid function.
Biapenem is a carbapenem antibiotic in which the azetidine and pyrroline rings carry 1-hydroxymethyl and pyrazolo[1,2-a][1,2,4]triazolium-6-ylthio substituents respectively. It has a role as an antibacterial drug. It is a member of carbapenems, a pyrazolotriazole and an organic sulfide.|Biapenem has been used in trials studying the treatment of Bacterial Infections.|Biapenem is a 1-beta-methylcarbapenem antibiotic with a wide range of antibacterial activity. Biapenem has similar antibacterial activity to that of imipenem, but is more stable against human renal dehydropeptidase-I and with less neurotoxicity.CertificatesBasic Info-
Product Name:
Biapenem
Other Name:5H-Pyrazolo[1,2-a][1,2,4]triazol-4-ium,6-[[(4R,5S,6S)-2-carboxy-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-en-3-yl]thio]-6,7-dihydro-,inner salt;5H-Pyrazolo[1,2-a][1,2,4]triazol-4-ium,6-[[2-carboxy-6-(1-hydroxyethyl)-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-en-3-yl]thio]-6,7-dihydro-,inner salt,[4R-[4α,5β,6β(R*)]]-;1-Azabicyclo[3.2.0]heptane,5H-pyrazolo[1,2-a][1,2,4]triazol-4-ium deriv.;LJC 10627;L 627;6-[[(4R,5S,6S)-2-Carboxy-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-en-3-yl]thio]-6,7-dihydro-5H-pyrazolo[1,2-a]-s-triazol-4-ium hydroxide,inner salt;CL 186815;Biapenem;Biapenern;CL 186-815;Omegacin;103939-78-2;133279-57-9
CAS No.:120410-24-4
Molecular Formula:C15H18N4O4S
InChIKeys:InChIKey=MRMBZHPJVKCOMA-YJFSRANCSA-N
Molecular Weight:350.39
Exact Mass:350.104889
EC Number:204-352-8
UNII:YR5U3L9ZH1
DSSTox ID:DTXSID5046435
NCI Thesaurus Code:C72620
ATC Code:J - Antiinfectives for systemic use
Categories:
Characteristics-
PSA:
128
XLogP3:1.4
Appearance:white to beige
Melting Point:265-271°C (dec.)
Refractive Index:1.651
Water Solubility:H2O: ≥5mg/mL (warmed)
Storage Conditions:-20°C Freezer
Specific rotation:D20 -32.9° (c = 0.5)
Hazard IdentificationClassification of the substance or mixture
no data available
GHS label elements, including precautionary statements
Pictogram(s) no data available Signal word no data available
Hazard statement(s) no data available
Precautionary statement(s) Prevention no data available
Response no data available
Storage no data available
Disposal no data available
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
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Seller Information
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Business Type:
Manufactory
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Main Products:
Herb Extracts,Cosmetic raw materails,API
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Location:
1403,Jinye B Block
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Payment Terms:
TT against copy of documents
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Average lead Time:
8
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Total Annual Revenue:
$2.5 million-$5 million
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Total Employees:
11-50
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Year of Establishment:
2015
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Inquiry History2 Inquiries
Country Product Purchase Quantity Date Posted
Pakistan
Biapenem API
2 KG Aug 8, 2025
India
Carbapenem Antibodies (powder)
1.00 G Dec 16, 2025 Post an enquiry for this product