NOSCAPINEHYDROCHLORIDE
912-60-7
Pharmaceutical Grade
99%
Shanghai
Pharma;Conutrix
25kg/Cardboard Drum
Yes
2024-07-31
Chemical Pesticides,Food Additives,Agrochemicals,Active Pharm Ingredients,Flavors and Fragrances,Chemical Catalyst
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Product Description
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Seller Information
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DescriptionECHEMI Editorial ReferenceWhite or almost white, crystalline powder or colourless crystals, hygroscopic.
Noscapine Hydrochloride is the orally available hydrochloride salt of the opioid agonist noscapine, a phthalideisoquinoline alkaloid derived from the opium poppy Papaver somniferum, with mild analgesic, antitussive, and potential antineoplastic activities. Noscapine binds to tubulin and alters its conformation, resulting in a disruption of the dynamics of microtubule assembly (by increasing the time that microtubules spend idle in a paused state) and subsequently, the inhibition of mitosis and tumor cell death. Unlike other tubulin inhibitors such as the taxanes and vinca alkaloids, noscapine does not affect microtubule polymerization.|A naturally occurring opium alkaloid that is a centrally acting antitussive agent.Basic Info-
Product Name:
Noscapine hydrochloride
Other Name:1(3H)-Isobenzofuranone,6,7-dimethoxy-3-[(5R)-5,6,7,8-tetrahydro-4-methoxy-6-methyl-1,3-dioxolo[4,5-g]isoquinolin-5-yl]-,hydrochloride (1:1),(3S)-;Narcotine,hydrochloride;1(3H)-Isobenzofuranone,6,7-dimethoxy-3-(5,6,7,8-tetrahydro-4-methoxy-6-methyl-1,3-dioxolo[4,5-g]isoquinolin-5-yl)-,hydrochloride,[S-(R*,S*)]-;1(3H)-Isobenzofuranone,6,7-dimethoxy-3-[(5R)-5,6,7,8-tetrahydro-4-methoxy-6-methyl-1,3-dioxolo[4,5-g]isoquinolin-5-yl]-,hydrochloride,(3S)-;1,3-Dioxolo[4,5-g]isoquinoline,1(3H)-isobenzofuranone deriv.;l-Narcotine hydrochloride;Noscapine hydrochloride;Opianine hydrochloride;11035-01-1
CAS No.:912-60-7
Molecular Formula:C22H23NO7.ClH
InChIKeys:InChIKey=MFLVZFXCSKVCSH-URBRKQAFSA-N
Molecular Weight:449.88
Exact Mass:449.124115
EC Number:213-014-9
DSSTox ID:DTXSID6073239
NCI Thesaurus Code:C61103
Categories:
Characteristics-
PSA:
75.69000
XLogP3:3.62170
Density:1.332g/cm3
Melting Point:190-191 °C
Boiling Point:565.3ºC at 760mmHg
Flash Point:295.7ºC
Storage Conditions:2-8°C
Toxicity:cyt-ham:fbr 60 mg/L ESKHA5 96,55,78
Hazard IdentificationClassification of the substance or mixture
Acute toxicity - Category 4, Oral
GHS label elements, including precautionary statements
Pictogram(s) 
Signal word Warning
Hazard statement(s) H302 Harmful if swallowed
Precautionary statement(s) Prevention P264 Wash ... thoroughly after handling.
P270 Do not eat, drink or smoke when using this product.
Response P301+P317 IF SWALLOWED: Get medical help.
P330 Rinse mouth.
Storage none
Disposal P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
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Seller Information
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Business Type:
Manufactory
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Main Products:
Chemical Pesticides,Food Additives,Agrochemicals,Active Pharm Ingredients,Flavors and Fragrances,Chemical Catalyst
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Location:
https://www.dideu.com/en/
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Payment Terms:
TT against copy of documents,D/P,L/C,D/A,O/A,TT against B/L draft before shipment,100% TT in advance
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Average lead Time:
7 days
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Total Annual Revenue:
Above $100 million
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Total Employees:
Above 1000
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Year of Establishment:
2016
Company Certificates-
ISO Certificate
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REACH
">Company Profile -
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Country Product Purchase Quantity Date Posted Post an enquiry for this product
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