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Home > Pharmaceutical Intermediates > Bulk Drug Intermediates > Pregabalin for Sale > Pregabalin 99% white Powder Professional Producer Greenbo
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Pregabalin 99% white Powder Professional Producer Greenbo

282 Inquiries

Unit Price: Get Latest Price
CAS No.:

148553-50-8

Grade:

Pharmaceutical Grade

Content:

99%

Port:

Shanghai

Brand:

Greenbo

Packaging:

25kg Drum

Price valid (until):

2022-07-31

Company Type:
Manufactory
Location:
China
Payment Terms:
TT against copy of documents,L/C,TT against B/L draft before shipment,100% TT in advance
Average Lead Time:
15 days
Qualification:
Main Products:

Active Pharm Ingredients,Chemical Catalyst,Pharmaceutical Intermediates,Flavors and Fragrances,Agrochemicals,Chemical Pesticides

  • Product Description

  • Seller Information

  • Inquiry History

  • Description

    High quality Certified Producer Pregabalin CAS 148553-50-8

    Our Reference Specification, for more details, pls contact us for COA,MSDS and certification:

    Skype: Avgem_alic Mobile:+86-18192575886; Whatsapp&Wechat: +8618192575886 Mail: mailto:Market@greenbo-biochem.com


    Item

    Standard

    Test Results

    Identification

    A.H-NMR:Comply with the structure

    Complies

    B.LC-MS:Comply with the structure

    Complies

    C.The IR spectrum of sample should be identical with that of reference standard.

    Complies

    D.HPLC-ESI-MSThe retention time of the major peak in the chromatogram of the Assay preparation corresponds to that in the chromatogram of the Standard preparation, as obtained in the Assay.

    Complies

    Crystallinity

    meets the requirements.

    Complies

    Loss on drying

    ≤2.0%

    0.19%

    Heavy metals

    ≤10 ppm

    <10ppm

    Water

    ≤1.0%

    0.1%

    Sulphated ash

    ≤0.5% determined on 1.0 g.

    0.009%

    Residue on ignition

    ≤0.1%

    0.03%

    Related Substances

    Unspecified impurities: for each impurity ≤0.10%

    <0.10%

    Total Impurity ≤0.5%

    0.18%

    Purity

    ≥99.0%

    99.7%

    Assay

    99.0%~101.0% (anhydrous substance).

    99.8%



    Microbiological Analysis

    Total plate count ≤1000cfu/g

    Complies

    Yeast & Moulds ≤100cfu/g

    Complies

    E. Coli.  Absent

    Negative

    Salmonella  Absent

    Negative

    S.aureus  Absent

    Negative

    Storage

    Preserve in well-closed,light-resistant and airtight containers.

    Complies


    Our normal packaging is 25kgs/Drum

    The packaging can be customized. the shipping term can be by sea, by air, and sample or small quantity can be shipped by DHL, FEDEX, EMS and TNT.












    Q1: Is there any possible to use my appointed label or package?

     Re: Yes. If needed, we'd like to use label or package according to your requirement.
    Q2: Why should you buy from us not from other suppliers?
     High-quality products with reasonable price;

     Delivering consistent and reliable quality products on time.

     Warm Service and Best after-sale service from our professional team.

    Q3: Which kind of payment terms do you accept?

    A: For small order, you can pay by T/Tor PayPal. bulk order by T/T or L/C to our company account.

    Q4: Can you give me a discount price?

    Surely, it depends on your Qty.

    Q5. What services can we provide or why you choose Greenbo as your reliable partner in China?

    1.Greenbo biochem work 7×24 hours and your request and after-sale service will be processed by our professional staff on time

    2. Higher quality can be guaranteed. Greenbo biochem are reputed chemical manufacturer and are Certified by ISO 9001;2015. Quality is our life and Quality is the guarantee of long-term cooperation. In addition to advocating mediocre quality control, we will strengthen the principle of good quality control. In the process of delivering to customers, we will focus on the details, confirm the sample standards with customers, and ensure the unity of large goods and sample standards. We will have our own quality inspectors to conduct sampling inspection on large goods. We also welcome customers to entrust third-party sampling inspection. We are committed to solving some problems before loading the goods, so as to reduce unnecessary losses for both buyers and sellers.

    3.Best price can be guaranteed. As Greenbo are integrated pharmaceuticals and chemicals producer, the production cost can be controlled and price will be definitely more competitive than China trading companies.

    4. Best after-sales service can be supplied. Greenbo biochem have professional team for after-sales service. If you have any complaints for our product and sales. please contact us ASAP by mailto:account@greenbo-biochem.com





    Shaanxi Greenbo Biochem Co., Limited

    is located in the High-Tech Zone of Xi'an, Shaanxi Province. which is a world-class innovation company and core competencies in the fields of health care and farm chemical. Since 2002 we are the high-tech corporation with GMP and ISO9001:2008 specializing in the production and research of farm chemical and its intermediates, Nutritional supplement and plant extract for pharmaceutical, Food, beverage, Cosmetic industry. With our innovative products, we are contributing to finding solutions to some of the major challenges of our time. The growing and increasingly aging world population requires improved medical care and an adequate supply of food. Greenbo is improving people’s quality of life by preventing, alleviating and treating diseases. And we are helping to provide a reliable supply of high quality green agricultural chemical, high-quality food, feed additive and plant-based raw materials. We develop new molecules for use in innovative products and solutions to improve health. By strict standing with the current GMP and tight QC procedures, with our skilled personal and special equipment, we saved the cost during production, make the manufacture effectiveness and also worked out with innovative pharmaceutical, food, cosmetic products. We also focus on the quality control and technology innovation. Greenbo R& D Center has a dedicated professional team tracking every step in our production. Up to now our center has developed long term cooperation with the professors, experts from Xi'an Jiao Tong University, Zhejiang University, engaging to the research and develop of the latest technology and new products.

    At Greenbo, we insist the principle of Top quality, Excellent Service, Outstanding technology innovation, Constantly develop. And our consistent objective is mutually benefit and win-win with customers and developing together, our code of practice for customer service is to make conveniences and benefit for customers; we do concern for customers, and searching solution of difficult problems from market feedbacks, so as to provide better service and tailored technical support, expanding our market and establish reputations. Our sales network covers 29 provinces in china. And internationally, our products were exported to Europe, America, Australia, Russia, Japan, Korea, and southeast Asia. Good commercial integrity and stable customer group make Greenbo to extend our business to the whole world. We sincerely welcome you to join us and create and even brighter future with you together.


    ECHEMI Editorial Reference
    Off-White SolidPregabalin is a second- generation antiepileptic drug (AED) known with the proprietary brand name of Lyrica (Pfizer, Tadworth) in the UK and USA (Pfizer, New York, NY). As a follow-up to its g-aminobutyric acid (GABA) agonist gabapentin, Pfizer hasdeveloped and launched pregabalin for the treatment of epilepsy and neuropathicpain. Although pregabalin is a structural analog of GABA, it does not interact withGABA-A or GABA-B receptors or influence GABA uptake. The exact mec
    Solid
    Pregabalin is a gamma-amino acid that is gamma-aminobutyric acid (GABA) carrying an isobutyl substitutent at the beta-position (the S-enantiomer). Binds with high affinity to the alpha2-delta site (an auxiliary subunit of voltage-gated calcium channels) in central nervous system tissues. It has a role as an anticonvulsant and a calcium channel blocker. It derives from a gamma-aminobutyric acid.|Pregabalin is a DEA Schedule V controlled substance. Substances in the DEA Schedule V have a low potential for abuse relative to substances listed in Schedule IV and consist primarily of preparations containing limited quantities of certain narcotics.|Pregabalin is structurally similar to gamma-aminobutyric acid (GABA) - an inhibitory neurotransmitter. It may be used to manage neuropathic pain, postherpetic neuralgia, and fibromyalgia among other conditions. Although as per the FDA Label the mechanism of action has not been definitively defined, there is evidence that pregabalin exerts its effects by binding to the α2δ subunit of voltage-dependent calcium channels. Pregabalin is marketed by Pfizer under the trade name Lyrica and Lyrica Cr (extended release). It may have dependence liability if misused but the risk appears to be highest in patients with current or past substance use disorders.|Pregabalin is an inhibitor of neuronal activity used for therapy of painful neuropathy and as an anticonvulsant. Therapy with pregabalin is not associated with serum aminotransferase elevations, and clinically apparent liver injury from pregabalin has been reported but appears to be quite rare.|Pregabalin is a 3-isobutyl derivative of gamma-amino butyric acid (GABA) with anti-convulsant, anti-epileptic, anxiolytic, and analgesic activities. Although the exact mechanism of action is unknown, pregabalin selectively binds to alpha2delta (A2D) subunits of presynaptic voltage-dependent calcium channels (VDCCs) located in the central nervous system (CNS). Binding of pregabalin to VDCC A2D subunits prevents calcium influx and the subsequent calcium-dependent release of various neurotransmitters, including glutamate, norepinephrine, serotonin, dopamine, and substance P, from the presynaptic nerve terminals of hyperexcited neurons; synaptic transmission is inhibited and neuronal excitability is diminished. Pregabalin does not bind directly to GABA-A or GABA-B receptors and does not alter GABA uptake or degradation.|A gamma-aminobutyric acid (GABA) derivative that functions as a CALCIUM CHANNEL BLOCKER and is used as an ANTICONVULSANT as well as an ANTI-ANXIETY AGENT. It is also used as an ANALGESIC in the treatment of NEUROPATHIC PAIN and FIBROMYALGIA.

    Basic Info
    Product Name:

    Pregabalin

    Other Name:

    Hexanoic acid,3-(aminomethyl)-5-methyl-,(3S)-;Hexanoic acid,3-(aminomethyl)-5-methyl-,(S)-;(3S)-3-(Aminomethyl)-5-methylhexanoic acid;PD 144723;CI 1008;Pregabalin;Lyrica;(S)-Pregabalin;(S)-(+)-3-(Aminomethyl)-5-methylhexanoic acid;(2S)-3-(Aminomethyl)-5-methylhexanoic acid;Gabanext 75;Pregalin 75;Neugaba 75;Maxgalin 75;Mahagaba-75;(S)-3-(Aminomethyl)-5-methylhexanoic acid

    CAS No.:

    148553-50-8

    Molecular Formula:

    C8H17NO2

    InChIKeys:

    InChIKey=AYXYPKUFHZROOJ-ZETCQYMHSA-N

    Molecular Weight:

    159.22600

    Exact Mass:

    159.23

    EC Number:

    604-639-1

    UNII:

    55JG375S6M

    DEA Code Number:

    2782

    DSSTox ID:

    DTXSID1045950

    NCI Thesaurus Code:

    C64625

    Color/Form:

    White to off-white crystalline solid

    ATC Code:

    N03AX16|QN03AX16|N - Nervous system

    HScode:

    2915900090

    Characteristics
    PSA:

    63.32000

    XLogP3:

    1.78240

    Appearance:

    Solid

    Density:

    0.997 g/cm3

    Melting Point:

    195 °C (decomp) @ Solvent: Isopropanol

    Boiling Point:

    274ºC at 760 mmHg

    Flash Point:

    119.5ºC

    Refractive Index:

    1.464

    Water Solubility:

    deionized water: ≥10mg/mL

    Storage Conditions:

    Store at 25 deg C (77 deg F); excursions permitted to 15 to 30 deg C (59 to 86 deg F).

    Vapor Pressure:

    0.00153mmHg at 25°C

    Specific rotation:

    Specific optical rotation = +10.52 deg/D (c = 1.00 in water)

    Henrys Law Constant:

    Henry's Law constant = 6.89X10-11 atm-cu m/mol at 25 °C (est)

    Dissociation Constants:

    pKa1 = 4.2; pKa2 = 10.6

    Experimental Properties:

    The log of the partition coefficient (n-octanol/0.05M phosphate buffer) at pH 7.4 is -1.35|Hydroxyl radical reaction rate constant = 4.1X10-11 cu cm/molec-sec at 25 °C (est)

    Hazard Identification

    Classification of the substance or mixture

    Serious eye damage, Category 1

    Reproductive toxicity, Category 2

    Specific target organ toxicity – repeated exposure, Category 2

    GHS label elements, including precautionary statements

    Pictogram(s)
    Signal word

    Danger

    Hazard statement(s)

    H318 Causes serious eye damage

    H361 Suspected of damaging fertility or the unborn child

    H373 May cause damage to organs through prolonged or repeated exposure

    Precautionary statement(s)
    Prevention

    P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...

    P203 Obtain, read and follow all safety instructions before use.

    P260 Do not breathe dust/fume/gas/mist/vapours/spray.

    Response

    P305+P354+P338 IF IN EYES: Immediately rinse with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

    P317 Get medical help.

    P318 IF exposed or concerned, get medical advice.

    P319 Get medical help if you feel unwell.

    Storage

    P405 Store locked up.

    Disposal

    P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

    Other hazards which do not result in classification

    no data available

    Handling and Storage

    Precautions for safe handling

    Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

    Conditions for safe storage, including any incompatibilities

    Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

  • Seller Information
    Business Type:

    Manufactory

    Main Products:

    Active Pharm Ingredients,Chemical Catalyst,Pharmaceutical Intermediates,Flavors and Fragrances,Agrochemicals,Chemical Pesticides

    Location:

    Zone K,Zwei Tianyuan Dushi Est,New Industial Park,High-tech Zone, Xian City,Shaanxi

    Payment Terms:

    TT against copy of documents,L/C,TT against B/L draft before shipment,100% TT in advance

    Average lead Time:

    15 days

    Total Annual Revenue:

    $2.5 million-$5 million

    Total Employees:

    11-50

    Year of Establishment:

    2017

    Company Certificates
    • Greenbo Biocheminternational trade license international trade license
    • Greenbo BiochemFSSC2000 FSSC2000

    Shaanxi Greenbo Biochem Co., Limited

    is located in the High-Tech Zone of Xi'an, Shaanxi Province. which is a world-class innovation company and core competencies in the fields of health care and farm chemical. Since 2002 we are the high-tech corporation with GMP and ISO9001:2008 specializing in the production and research of farm chemical and its intermediates, Nutritional supplement and plant extract for pharmaceutical, Food, beverage, Cosmetic industry. With our innovative products, we are contributing to finding solutions to some of the major challenges of our time. The growing and increasingly aging world population requires improved medical care and an adequate supply of food. Greenbo is improving people’s quality of life by preventing, alleviating and treating diseases. And we are helping to provide a reliable supply of high quality green agricultural chemical, high-quality food, feed additive and plant-based raw materials. We develop new molecules for use in innovative products and solutions to improve health. By strict standing with the current GMP and tight QC procedures, with our skilled personal and special equipment, we saved the cost during production, make the manufacture effectiveness and also worked out with innovative pharmaceutical, food, cosmetic products. We also focus on the quality control and technology innovation. Greenbo R& D Center has a dedicated professional team tracking every step in our production. Up to now our center has developed long term cooperation with the professors, experts from Xi'an Jiao Tong University, Zhejiang University, engaging to the research and develop of the latest technology and new products.

    At Greenbo, we insist the principle of Top quality, Excellent Service, Outstanding technology innovation, Constantly develop. And our consistent objective is mutually benefit and win-win with customers and developing together, our code of practice for customer service is to make conveniences and benefit for customers; we do concern for customers, and searching solution of difficult problems from market feedbacks, so as to provide better service and tailored technical support, expanding our market and establish reputations. Our sales network covers 29 provinces in china. And internationally, our products were exported to Europe, America, Australia, Russia, Japan, Korea, and southeast Asia. Good commercial integrity and stable customer group make Greenbo to extend our business to the whole world. We sincerely welcome you to join us and create and even brighter future with you together.
  • Inquiry History
    282 Inquiries
    Country Product Purchase Quantity Date Posted
    Oman

    White Crystalline powder Pregabalin Lyrica 148553-50-8 HALAL ISO

    1 KG Jan 16, 2024
    United Arab Emirates

    Pregabalin CAS 148553-50-8

    1 KG Jan 20, 2024
    United States

    Pregabalin powder CAS 148553-50-8

    3 G Oct 29, 2023
    Turkey

    Pregabalin powder CAS 148553-50-8

    1 KG Oct 9, 2023
    United Arab Emirates

    Pregabalin powder CAS 148553-50-8

    1 KG Sep 25, 2023
    Netherlands

    Pregabalin powder CAS 148553-50-8

    10 KG Sep 27, 2023
    Saudi Arabia

    CAS 148553-50-8 Lyrica Pregabalin wego

    2 KG Sep 23, 2023
    United States

    High Quality Pregabalin 99% powder 148553-50-8

    222 G Jul 4, 2024
    Algeria

    99% White Crystalline powder Pregabalin Lyrica 148553-50-8

    400 G Jun 11, 2025
    United States

    99% White Crystalline powder Pregabalin Lyrica 148553-50-8

    1 MT Nov 18, 2023
    Poland

    Research Chemical 99.5% Pregabalin Powder CAS: 148553-50-8

    100 G Nov 9, 2023
    United States

    Best Price Pregabalin CAS 148553-50-8 In Stock

    1 G Nov 4, 2023
    Sweden

    High Purity Pregabalin CAS 148553-50-8 Crystalline powder

    500 G Feb 16, 2026
    Finland

    Best Price Pregabalin CAS 148553-50-8 In Stock

    1 KG Sep 24, 2023
    Lebanon

    Pregabalin 99% White Powder CAS 148553-50-8 Pregabalin powder

    1 KG Dec 4, 2023
    Saudi Arabia

    hot sell pregabalin lyrica pregabalin powder CAS 148553-50-8

    300 G Oct 22, 2023
    Qatar

    hot sell pregabalin lyrica pregabalin powder CAS 148553-50-8

    1 MT Nov 5, 2023
    United Arab Emirates

    hot sell pregabalin lyrica pregabalin powder CAS 148553-50-8

    1 KG Nov 1, 2023
    Turkey

    High Purity in Stock Pregabalin CAS 148553-50-8 99%

    100 KG Oct 29, 2023
    Oman

    hot sell pregabalin lyrica pregabalin powder CAS 148553-50-8

    1 KG Oct 4, 2023
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