Tolazoline hydrochloride 99% high purity certified Professional Producer Greenbo
59-97-2
Pharmaceutical Grade
99%
Shanghai
Greenbo
25kg Drum
2022-07-31
Active Pharm Ingredients,Chemical Catalyst,Pharmaceutical Intermediates,Flavors and Fragrances,Agrochemicals,Chemical Pesticides
-
Product Description
-
Seller Information
-
DescriptionECHEMI Editorial ReferenceTolazoline(NSC35110; Imidaline) Hcl is a non-selective competitive α-adrenergic receptor antagonist.IC50 value:Target: α-adrenoceptor antagonistTolazoline can be synthesized by the heterocyclation of the ethyl ester of iminophenzylacetic acid with ethylene diamine, which forms the desired product. The structure of tolazoline is strikingly similar to α-adrenergic agonists, which are antiedema sympathomimetics.
Tolazoline hydrochloride is a member of benzenes.|A vasodilator that apparently has direct actions on blood vessels and also increases cardiac output. Tolazoline can interact to some degree with histamine, adrenergic, and cholinergic receptors, but the mechanisms of its therapeutic effects are not clear. It is used in treatment of persistent pulmonary hypertension of the newborn.Basic Info-
Product Name:
Tolazoline hydrochloride
Other Name:1H-Imidazole,4,5-dihydro-2-(phenylmethyl)-,hydrochloride (1:1);2-Imidazoline,2-benzyl-,monohydrochloride;1H-Imidazole,4,5-dihydro-2-(phenylmethyl)-,monohydrochloride;Arterodyl;Benzazoline hydrochloride;Imidaline hydrochloride;Priscoline hydrochloride;Tolavad;Tolazoline chloride;Tolazoline hydrochloride;Tolpal;2-Benzyl-4,5-dihydroimidazole hydrochloride;2-Benzyl-2-imidazoline hydrochloride;2-Benzylimidazoline hydrochloride;Totazoline;Lambral;Vaso-Dilatan;2-Benzyl-4,5-dihydro-1H-imidazole hydrochloride;7380-28-1;245547-27-7
CAS No.:59-97-2
Molecular Formula:C10H12N2.ClH
InChIKeys:InChIKey=RHTNTTODYGNRSP-UHFFFAOYSA-N
Molecular Weight:196.68
Exact Mass:196.076721
EC Number:200-447-3
UNII:E669Z6S1JG
NSC Number:757353
DSSTox ID:DTXSID9021718
HScode:2933290090
Categories:
Characteristics-
PSA:
24.4
XLogP3:1.79720
Appearance:White to almost white Crystalline Powder
Density:1.09g/cm3
Melting Point:174 °C
Boiling Point:338.2ºC at 760mmHg
Flash Point:158.3ºC
Storage Conditions:-20°C Freezer, Under Inert Atmosphere
Toxicity:Oral-large LD50: 1200 mg/kg; Oral-Mouse LD50: 400 mg/kg
Flammability characteristics:Combustion produces toxic nitrogen oxides and hydrogen chloride fumes; drug side effects; rapid heartbeat, sweating, bleeding from 12 fingers, small intestine, ulcers
Collision Cross Section:135.1 Ų [M+H]+ [CCS Type: TW, Method: calibrated with polyalanine and drug standards]
Hazard IdentificationClassification of the substance or mixture
Acute toxicity - Category 4, Oral
Skin irritation, Category 2
Eye irritation, Category 2
Specific target organ toxicity â single exposure, Category 3
GHS label elements, including precautionary statements
Pictogram(s)
Signal word Warning
Hazard statement(s) H302 Harmful if swallowed
H315 Causes skin irritation
H319 Causes serious eye irritation
H335 May cause respiratory irritation
Precautionary statement(s) Prevention P264 Wash ... thoroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P271 Use only outdoors or in a well-ventilated area.
Response P301+P317 IF SWALLOWED: Get medical help.
P330 Rinse mouth.
P302+P352 IF ON SKIN: Wash with plenty of water/...
P321 Specific treatment (see ... on this label).
P332+P317 If skin irritation occurs: Get medical help.
P362+P364 Take off contaminated clothing and wash it before reuse.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing.
P319 Get medical help if you feel unwell.
Storage P403+P233 Store in a well-ventilated place. Keep container tightly closed.
P405 Store locked up.
Disposal P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
-
-
Seller Information
-
Business Type:
Manufactory
-
Main Products:
Active Pharm Ingredients,Chemical Catalyst,Pharmaceutical Intermediates,Flavors and Fragrances,Agrochemicals,Chemical Pesticides
-
Location:
Zone K,Zwei Tianyuan Dushi Est,New Industial Park,High-tech Zone, Xian City,Shaanxi
-
Payment Terms:
TT against copy of documents,L/C,TT against B/L draft before shipment,100% TT in advance
-
Average lead Time:
15 days
-
Total Annual Revenue:
$2.5 million-$5 million
-
Total Employees:
11-50
-
Year of Establishment:
2017
Company Certificates-
international trade license
-
FSSC2000
-
-
Country Product Purchase Quantity Date Posted Post an enquiry for this product
More from this Seller
-
-
-
Guaiacol from Greenbo biochem
Pharmaceutical Grade / 99%
-
-
-
-
2-(2-HEXYLOXYETHOXY)ETHANOL 99% high purity certified Professional producer Greenbo
Industrial Grade / 99%
-
-
-
-
3-Chloropropionyl chloride 99% high purity certified Professional Producer Greenbo
Pharmaceutical Grade / 99%
-
-
-
-
Ethyl diphenylphosphinite 98% colorless liquid GB4284 Greenbo
Pharmaceutical Grade / 98%
-

















