Promethazine hydrochloride
14 Inquiries
58-33-3
99%
Bottle,barrel,cargo,container,etc.
2026-06-26
Intermediates,Building blocks,API,Silicones,Peptides,Lab chemicals
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Product Description
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Seller Information
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Inquiry History
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DescriptionKeywords
58-33-3
Promethazine hydrochloride
C17H20N2S.HCl
Quick DetailsProName:Promethazine hydrochloride
CasNo:58-33-3
Molecular Formula:C17H20N2S.HCl
Appearance:powder, or liquid
Application:Pharmaceuticals, intermediates, APIs, custom synthesis, chemicals
DeliveryTime:5-7 Days
PackAge:Bottle, barrel, cargo, container, etc.
Port:Shanghai
Purity:99
Storage:Stored in room temperature, ventilated place
Transportation:By air, ship, express, etc.
LimitNum:0
Grade:Industrial Grade
SuperiorityBest Seller, High Quality, Competitive Price, Fast Delivery, Quick Response
DetailsLEAPChem supplies high quality Pharmaceuticals, intermediates, APIs, custom synthesis, fine chemicals and other industrial chemicalsBasic Info-
Product Name:
Promethazine hydrochloride
Other Name:10H-Phenothiazine-10-ethanamine,N,N,α-trimethyl-,hydrochloride (1:1);Phenothiazine,10-[2-(dimethylamino)propyl]-,monohydrochloride;10H-Phenothiazine-10-ethanamine,N,N,α-trimethyl-,monohydrochloride;10-[2-(Dimethylamino)propyl]phenothiazine hydrochloride;Plletia;Promethazine hydrochloride;Phenergan;Promethazine chloride;Promethazine monohydrochloride;Atosil;Fenergan;Diprazin;Pipolfen;Diprasine;Romergan;Pipolphen;Romergan hydrochloride;Kinetosin;Pyrethia;Promethazinium chloride;Phena;Promasun;Hiberna;Phencen;Dorme;Phenergan VC;Fellozine;Remsed;Lergigan;Genphen;Prorex;Fenazil;Anergan 25;Anergan 50;Duplamin;Prothazine;Mepergan;Provigan;Phanergan D;NSC 231688;Himazin;16639-38-6;88208-28-0
CAS No.:58-33-3
Molecular Formula:C17H20N2S.ClH
InChIKeys:InChIKey=XXPDBLUZJRXNNZ-UHFFFAOYSA-N
Molecular Weight:320.88
Exact Mass:320.111389
EC Number:200-375-2
NSC Number:757301|231688
DSSTox ID:DTXSID3021192
HScode:2933699090
Categories:
Characteristics-
PSA:
31.8
XLogP3:5.10640
Appearance:Promethazine hydrochloride is an odorless white to faint yellow crystalline powder. Bitter taste. A 10% solution in water has a pH of 3.5-5.0. (NTP, 1992)
Density:1.131 g/cm3
Melting Point:230-232 °C
Boiling Point:403.7ºC at 760 mmHg
Flash Point:9℃
Water Solubility:In water, 1.56X10-2 g/L (15.6 mg/L) at 24 deg C
Storage Conditions:Refrigerator
Vapor Pressure:1.03X10-5 mm Hg at 25 deg C (est)
Toxicity:LD50 i.v. in mice: 55.0 mg/kg (Rajsner)
Collision Cross Section:162.7 Ų [M+H]+ [CCS Type: TW, Method: calibrated with polyalanine and drug standards]
Air and Water Reactions:Slowly oxidizes in air, acquiring a blue color. Also turns blue on exposure to moisture. Water soluble.
Reactive Group:Amines, Phosphines, and Pyridines
Reactivity Profile:PROMETHAZINE HYDROCHLORIDE is sensitive to light. In aqueous solution, it is degraded by heat and light (more rapidly in air or oxygen). Incompatible with alkalis and alkaline solutions such as those of aminophylline, soluble barbiturates and phenytoin sodium. Iron(III) and copper(III) accelerate the degradation (NTP, 1992).
Hazard IdentificationClassification of the substance or mixture
Acute toxicity - Category 4, Oral
Skin irritation, Category 2
Skin sensitization, Category 1
Eye irritation, Category 2
Acute toxicity - Category 4, Inhalation
Specific target organ toxicity â single exposure, Category 3
Hazardous to the aquatic environment, long-term (Chronic) - Category Chronic 2
GHS label elements, including precautionary statements
Pictogram(s) 
Signal word Warning
Hazard statement(s) H302 Harmful if swallowed
H315 Causes skin irritation
H317 May cause an allergic skin reaction
H319 Causes serious eye irritation
H332 Harmful if inhaled
H335 May cause respiratory irritation
H411 Toxic to aquatic life with long lasting effects
Precautionary statement(s) Prevention P264 Wash ... thoroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P272 Contaminated work clothing should not be allowed out of the workplace.
P271 Use only outdoors or in a well-ventilated area.
P273 Avoid release to the environment.
Response P301+P317 IF SWALLOWED: Get medical help.
P330 Rinse mouth.
P302+P352 IF ON SKIN: Wash with plenty of water/...
P321 Specific treatment (see ... on this label).
P332+P317 If skin irritation occurs: Get medical help.
P362+P364 Take off contaminated clothing and wash it before reuse.
P333+P317 If skin irritation or rash occurs: Get medical help.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing.
P317 Get medical help.
P319 Get medical help if you feel unwell.
P391 Collect spillage.
Storage P403+P233 Store in a well-ventilated place. Keep container tightly closed.
P405 Store locked up.
Disposal P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Promethazine hydrochloride preparations should be protected from light. Promethazine hydrochloride oral solution and tablets should be stored in tight, light-resistant containers at 15-30 and 20-25 deg C, respectively, while the rectal suppositories should be stored in well-closed containers at 2-8 deg C. Freezing of the oral solution should be avoided. Following the date of manufacture, commercially available promethazine preparations have expiration dates of 2-5 years depending on the dosage form and manufacturer.
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Seller Information
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Business Type:
Trader
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Main Products:
Intermediates,Building blocks,API,Silicones,Peptides,Lab chemicals
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Location:
Room A, 23rd Floor, No. 609 Yan'an Road, Gongshu District, Hangzhou, Zhejiang
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Payment Terms:
TT against copy of documents,D/P,L/C
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Average lead Time:
5
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Total Annual Revenue:
Above $100 million
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Year of Establishment:
2020
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Certifications:
ISO
">Company ProfileLEAPChem is a specialized fine chemical supplier for research, development and production.
LEAPChem provides nearly 200,000 rare and innovative chemical products to support the evolving needs of our customers in research & bulk manufacturing activities.
As a highly customer-oriented enterprise, we are committed to providing high-quality customer services and products to our global customers in a cost-effective and efficient manner.
Our client list includes many major pharmaceutical and science companies, universities, research institutions and chemical catalogue companies.
Methodology: Sound & Stable; Active & Innovative.
Attitude: Conscientious; Ingenious.
Goals: Customer's Satisfaction
We regard client's success as our success.
At LEAPChem, we strive to be the preferred supplier for efficiency increasing and cost lowering in your Research & Production.
To achieve this strategic vision, we always push ourselves to exceed our customer's requirement. By focusing on the aim of 'Beyond Your Expectation', we continually expand our product lines, and enhance our systematic management and human resources.
Welcome to contact us and we look forward to becoming your reliable and preferred partner.
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Inquiry History14 Inquiries
Country Product Purchase Quantity Date Posted 
Singapore
Promethazine hydrochloride CAS 58-33-3 with High purity 99% White powder 58-33-3 SENYI
1 KG Jun 29, 2023 
United Kingdom
Promethazine hydrochloride CAS 58-33-3 with High purity 99% White powder 58-33-3 SENYI
25 MT Jun 17, 2023 
United States
Hot Selling CAS 58-33-3 Promethazine hydrochloride with 99% Purity White Powder
1 MT Nov 6, 2023
United States
Promethazine HCl
1 Jun 3, 2025 
Canada
Promethazine hcl
1 KG Jan 2, 2024
United States
Promethazine
1 KG Jan 5, 2026
United States
USA UK Canada Europe etc 99% Pure Promethazine HCl Hydrochloride Powder CAS 58- 33-3 Safe Shipping
1 KG Dec 14, 2025 
Netherlands
Promethazine HCl
100 G Mar 11, 2025 
India
Promethazine Hydrochloride
25 G Oct 9, 2024
United Kingdom
Antihistamine Promethazine HCl Promethazine Hydrochloride Powder Raw Material 99% white powder Lingding-395 Lingding
15 G May 27, 2023 
Argentina
Promethazine hydrochloride
50 G Apr 15, 2026
United Kingdom
Promethazine HCL 99.9% powder
1 Jan 10, 2026
United States
Promethazine Hydrochloride
20 G Apr 10, 2025 
Kenya
promethazine Hcl
40 KG Dec 3, 2024 Post an enquiry for this product