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Dihexadecyl phosphate

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CAS No.:

2197-63-9

Content:

99%

Packaging:

Bottle,barrel,cargo,container,etc.

Sample Available:

Yes

Price valid (until):

2026-10-23

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HANGZHOU LEAP CHEM CO., LTD.

Company Type:

Trader

Location:

China

Payment Terms:

TT against copy of documents,D/P,L/C

Average Lead Time:

5 days

Qualification:

Main Products:

Intermediates,Building blocks,API,Silicones,Peptides,Lab chemicals

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Product Description
Seller Information

Description

Keywords

Dihexadecyl phosphate

2197-63-9

Quick Details

ProName:

Dihexadecyl phosphate

CasNo:

2197-63-9

Appearance:

powder, or liquid

Application:

Pharmaceuticals, intermediates, APIs, custom synthesis, chemicals

DeliveryTime:

5-7 Days

PackAge:

Bottle, barrel, cargo, container, etc.

Port:

Shanghai

Purity:

Storage:

Stored in room temperature, ventilated place

Transportation:

By air, ship, express, etc.

LimitNum:

Grade:

Industrial Grade

Superiority

Best Seller, High Quality, Competitive Price, Fast Delivery, Quick Response

Details

LEAPChem supplies high quality Pharmaceuticals, intermediates, APIs, custom synthesis, fine chemicals and other industrial chemicals

ECHEMI Editorial Reference

ChEBI: The dihexadecyl ester of phosphoric acid.
Dicetyl hydrogen phosphate is the dihexadecyl ester of phosphoric acid.

Basic Info

Product Name:

Dicetyl phosphate

Other Name:

1-Hexadecanol,1,1′-(hydrogen phosphate);1-Hexadecanol,hydrogen phosphate;Dicetyl phosphate;Dicetyl hydrogen phosphate;Dihexadecyl hydrogen phosphate;Dihexadecyl phosphate;Bis(hexadecyl) phosphate;Di(hexadecyl) monohydrogen phosphate;Di-n-hexadecyl phosphate;Phosphoric acid dihexadecyl ester;DAP 60H;NSC 12429;Crodafos CS 20A;CS 20A

CAS No.:

2197-63-9

Molecular Formula:

C32H67O4P

InChIKeys:

InChIKey=RNPXCFINMKSQPQ-UHFFFAOYSA-N

Molecular Weight:

546.85

Exact Mass:

546.85

EC Number:

218-594-7

UNII:

2V6E5WN99N

NSC Number:

12429

DSSTox ID:

DTXSID7062243

HScode:

2919900090

Categories:

Phosphines

Characteristics

PSA:

55.8

XLogP3:

14.5

Density:

0.9±0.1 g/cm3

Melting Point:

68-70 °C

Boiling Point:

600.4ºC at 760 mmHg

Flash Point:

316.9±26.8 °C

Refractive Index:

1.461

Storage Conditions:

−20°C

Vapor Pressure:

5.8E-09mmHg at 25°C

Research

Class:

Angiotensin IV-derived oligopeptide / HGF-c-Met potentiator

Status:

Research compound — Not FDA approved

Mechanism:

A synthetic, orally active, blood-brain-barrier-permeable oligopeptide (Hexanoyl-Tyr-Ile-Ahx-NH₂) derived from angiotensin IV. Dihexa binds hepatocyte growth factor (HGF) with high affinity (Kd = 65 pM) and allosterically potentiates HGF activity at its receptor c-Met, promoting dendritic spinogenesis and synaptogenesis. In preclinical models it was reported to be seven orders of magnitude more potent than BDNF at promoting synapse formation. Note: the foundational 2014 paper (McCoy AT, et al. Neurobiol Learn Mem. 2014) was retracted in 2025.

EC50 (HGF Binding KD):

65 pM

Activity note:

Dihexa is an HGF potentiator, not a direct receptor agonist. It does not activate c-Met alone but markedly augments HGF-induced c-Met activation at low nanomolar HGF concentrations. Functional synaptogenic activity was reported at 10⁻¹°–10⁻⁻ M (original data now subject to retraction).

Source:

Original report: McCoy AT, et al. Neurobiol Learn Mem. 2014;115:112-120 (retracted 2025). Benoist CC, et al. J Pharmacol Exp Ther. 2014;351(3):628-637.

Clinical Development:

NCT04488419

References

PubChem:

PubChem

UNII:

9WYX65A5C2

Literature:

Benoist CC, et al. J Pharmacol Exp Ther. 2014 — HGF/c-Met mechanism; McCoy AT, et al. Neurobiol Learn Mem. 2014 — Synaptogenesis data (Retracted 2025); Athira Pharma: Fosgonimeton (prodrug) pipeline status

Disclaimer:

Dihexa is NOT FDA-approved or EMA-approved as a medicine. It is a research compound only. The foundational 2014 paper describing its synaptogenic potency was retracted in 2025. Its phosphate prodrug fosgonimeton failed a Phase 2/3 Alzheimer’s trial (LIFT-AD, 2024). This listing is for industrial and laboratory research use only. It is not medical advice, a clinical recommendation, or an approved therapy description. Always verify regulatory status, purity, and intended use with the supplier and applicable authorities before purchase or use.

See More Dicetyl phosphate Properties 

Hazard Identification

Classification of the substance or mixture

Not classified.

GHS label elements, including precautionary statements

Precautionary statement(s)
Pictogram(s)	No symbol.
Signal word	No signal word
Hazard statement(s)	none
Prevention	none
Response	none
Storage	none
Disposal	none

Other hazards which do not result in classification

no data available

Handling and Storage

Precautions for safe handling

Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Conditions for safe storage, including any incompatibilities

Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

See More Dicetyl phosphate Safety Data Sheet 

Seller Information

Business Type:
Trader

Main Products:
Intermediates,Building blocks,API,Silicones,Peptides,Lab chemicals

Location:
Room A, 23rd Floor, No. 609 Yan'an Road, Gongshu District, Hangzhou, Zhejiang

Payment Terms:
TT against copy of documents,D/P,L/C

Average lead Time:
5 days

Total Annual Revenue:
Above $100 million

Year of Establishment:
2020

Company Certificates
- ISO
Company Profile
LEAPChem is a specialized fine chemical supplier for research, development and production.
LEAPChem provides nearly 200,000 rare and innovative chemical products to support the evolving needs of our customers in research & bulk manufacturing activities.
As a highly customer-oriented enterprise, we are committed to providing high-quality customer services and products to our global customers in a cost-effective and efficient manner.
Our client list includes many major pharmaceutical and science companies, universities, research institutions and chemical catalogue companies.

Methodology: Sound & Stable; Active & Innovative.
Attitude: Conscientious; Ingenious.
Goals: Customer's Satisfaction

We regard client's success as our success.
At LEAPChem, we strive to be the preferred supplier for efficiency increasing and cost lowering in your Research & Production.
To achieve this strategic vision, we always push ourselves to exceed our customer's requirement. By focusing on the aim of 'Beyond Your Expectation', we continually expand our product lines, and enhance our systematic management and human resources.
Welcome to contact us and we look forward to becoming your reliable and preferred partner.
LEAPChem is a specialized fine chemical supplier for research, development and production.
LEAPChem provides nearly 200,000 rare and innovative chemical products to support the evolving needs of our customers in research & bulk manufacturing activities.
As a highly customer-oriented enterprise, we are committed to providing high-quality customer services and products to our global customers in a cost-effective and efficient manner.
Our client list includes many major pharmaceutical and science companies, universities, research institutions and chemical catalogue companies.

Methodology: Sound & Stable; Active & Innovative.
Attitude: Conscientious; Ingenious.
Goals: Customer's Satisfaction

We regard client's success as our success.
At LEAPChem, we strive to be the preferred supplier for efficiency increasing and cost lowering in your Research & Production.
To achieve this strategic vision, we always push ourselves to exceed our customer's requirement. By focusing on the aim of 'Beyond Your Expectation', we continually expand our product lines, and enhance our systematic management and human resources.
Welcome to contact us and we look forward to becoming your reliable and preferred partner.
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Dihexadecyl phosphate

Product Description

Seller Information

Classification of the substance or mixture

GHS label elements, including precautionary statements

Other hazards which do not result in classification

Precautions for safe handling

Conditions for safe storage, including any incompatibilities

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