Topotecan
123948-87-8
99%
Bottle,barrel,cargo,container,etc.
2026-06-30
Intermediates,Building blocks,API,Silicones,Peptides,Lab chemicals
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Product Description
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Seller Information
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DescriptionKeywords
123948-87-8
Topotecan
C23H23N3O5
Quick DetailsProName:Topotecan
CasNo:123948-87-8
Molecular Formula:C23H23N3O5
Appearance:powder, or liquid
Application:Pharmaceuticals, intermediates, APIs, custom synthesis, chemicals
DeliveryTime:5-7 Days
PackAge:Bottle, barrel, cargo, container, etc.
Port:Shanghai
Purity:99
Storage:Stored in room temperature, ventilated place
Transportation:By air, ship, express, etc.
LimitNum:0
Grade:Industrial Grade
SuperiorityBest Seller, High Quality, Competitive Price, Fast Delivery, Quick Response
DetailsLEAPChem supplies high quality Pharmaceuticals, intermediates, APIs, custom synthesis, fine chemicals and other industrial chemicalsBasic Info-
Product Name:
Topotecan
Other Name:1H-Pyrano[3′,4′:6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione,10-[(dimethylamino)methyl]-4-ethyl-4,9-dihydroxy-,(4S)-;1H-Pyrano[3′,4′:6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione,10-[(dimethylamino)methyl]-4-ethyl-4,9-dihydroxy-,(S)-;(4S)-10-[(Dimethylamino)methyl]-4-ethyl-4,9-dihydroxy-1H-pyrano[3′,4′:6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione;Topotecan;Hycamptamine;SKF 104864;Topotecan lactone;SKF-S 104864;Hycamptin;NSC 609699;10-Hydroxy-9-[(dimethylamino)methyl]-(20S)-camptothecin;9-(N,N-Dimethylaminomethyl)-10-hydroxycamptothecin;(S)-Topotecan;Nogitecan;Topophore C;TopoCED;(19S)-8-[(Dimethylamino)methyl]-19-ethyl-7,19-dihydroxy-17-oxa-3,13-diazapentacyclo[11.8.0.0[2,11].0[4,9].0[15,20]]henicosa-1(21),2(11),3,5,7,9,15(20)-heptaene-14,18-dione;Potactasol;Evotopin;133242-28-1;138121-88-7
CAS No.:123948-87-8
Molecular Formula:C23H23N3O5
InChIKeys:InChIKey=UCFGDBYHRUNTLO-QHCPKHFHSA-N
Molecular Weight:421.45
Exact Mass:421.45
EC Number:231-595-7
UNII:7M7YKX2N15
NSC Number:641007
DSSTox ID:DTXSID3042685
NCI Thesaurus Code:C1413
ATC Code:L01CE01|L01XX17|L - Antineoplastic and immunomodulating agents
HScode:2942000000
Categories:
Characteristics-
PSA:
103
XLogP3:0.5
Appearance:yellow liquid
Density:1.5±0.1 g/cm3
Melting Point:−114 °C(lit.)
Boiling Point:>100 °C(lit.)
Flash Point:12 °C
Refractive Index:1.734
Water Solubility:H2O: soluble
Storage Conditions:2-8°C
Vapor Pressure:613 psi ( 21.1 °C)
Vapor Density:1.3 (vs air)
Henrys Law Constant:Henry's Law constant = 1.59X10-24 atm-cu m/mol at 25 °C (est)
Dissociation Constants:pKa1 = 1.74 (imine); pKa2 = 8.00 (benzyl alcohol); pKa3 = 9.83 (amine) (est)
Experimental Properties:Light yellow to greenish powder, mp 213-218 °C (decomposes). Soluble in water up to 1 mg/mL. Hygroscopic. Heant and light sensitive /Topotecan hydrochloride/|Hydroxyl radical reaction rate constant = 2.63X10-10 cu cm/molec-sec at 25 °C (est)|Ozone radical reaction rate constant = 1.16X10-15 cu cm/molec-sec at 25 °C (est)
Hazard IdentificationClassification of the substance or mixture
Germ cell mutagenicity, Category 2
GHS label elements, including precautionary statements
Pictogram(s) 
Signal word Warning
Hazard statement(s) H341 Suspected of causing genetic defects
Precautionary statement(s) Prevention P203 Obtain, read and follow all safety instructions before use.
P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...
Response P318 IF exposed or concerned, get medical advice.
Storage P405 Store locked up.
Disposal P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
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Seller Information
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Business Type:
Trader
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Main Products:
Intermediates,Building blocks,API,Silicones,Peptides,Lab chemicals
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Location:
Room A, 23rd Floor, No. 609 Yan'an Road, Gongshu District, Hangzhou, Zhejiang
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Payment Terms:
TT against copy of documents,D/P,L/C
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Average lead Time:
5
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Total Annual Revenue:
Above $100 million
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Year of Establishment:
2020
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Certifications:
ISO
">Company ProfileLEAPChem is a specialized fine chemical supplier for research, development and production.
LEAPChem provides nearly 200,000 rare and innovative chemical products to support the evolving needs of our customers in research & bulk manufacturing activities.
As a highly customer-oriented enterprise, we are committed to providing high-quality customer services and products to our global customers in a cost-effective and efficient manner.
Our client list includes many major pharmaceutical and science companies, universities, research institutions and chemical catalogue companies.
Methodology: Sound & Stable; Active & Innovative.
Attitude: Conscientious; Ingenious.
Goals: Customer's Satisfaction
We regard client's success as our success.
At LEAPChem, we strive to be the preferred supplier for efficiency increasing and cost lowering in your Research & Production.
To achieve this strategic vision, we always push ourselves to exceed our customer's requirement. By focusing on the aim of 'Beyond Your Expectation', we continually expand our product lines, and enhance our systematic management and human resources.
Welcome to contact us and we look forward to becoming your reliable and preferred partner.
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